Theses/Dissertations from 2023
Gap Junctional Intercellular Communication: Role of Cx43 Phosphorylation by Tyrosine Kinases, Ishika Basu
Exploiting Vulnerabilities in the Ras-Rac Signaling Pathway for the Selective Targeting of Pancreatic Cancer Cells, Neha Chaudhary
Examining CAF Heterogeneity in Pancreatic Cancer, Nidhi V. Dwivedi
MnTnBuOE-2-PyP Sensitizes Castrate Resistant Prostate Cancer to Androgen Deprivation Therapies, Ariel Moats
Theses/Dissertations from 2022
Metoprolol Disrupts Sterol Biosynthesis through Inhibition of 7-Dehydrocholesterol Reductase (DHCR7), Luke B. Allen
Mechanisms of Sorting and Fission at the Endosomes, Kanika Dhawan
Characterizing a MUC4-Based Nanovaccine and Enhancing its Efficacy by Targeting the Endothelin Axis, Mansi Gulati
Neuropilin-2 in Advanced Prostate Cancer and its Targeting with Novel Small Molecule Inhibitors, Ridwan Islam
Novel Molecular Mechanisms of C-Terminal Eps15 Homology Domain (EHD) Proteins in Endocytic Trafficking and Primary Ciliogenesis, Tyler M. Jones
The Role of Parkin in Mitochondrial DNA, Eliezer Lichter
Underlying Mechanism of Ovarian Reserve Preservation from Gonadotoxicity, Yi Luan
The Relationship between p66Shc Expression and Proliferation of Human Prostate Cancer Cells with MnTnBuOE-2-PyP Treatment, Thao Nhi Radik
PAF1/PD2 Augments Pancreatic Cancer Progression and Mediates Radiation and Chemoresistance, Sanchita Rauth
Dysregulation of miR-10a Promotes Cancer Features in Cholangiocarcinoma, Matthieu Spriet
Theses/Dissertations from 2021
Secreted Mucin 5AC-Mediated Epithelial and Stromal Modulations Augment Pancreatic Cancer Aggressiveness, Koelina Ganguly
Fibroblast Growth Factor Receptor 4 and R4-ICD Increased Proliferation, Cell Survival and Metastasis in Cholangiocarcinoma, Yamnah Hafeji
A PKCα-Mediated Growth Suppressive MEK-ERK Signaling Axis in Intestinal Epithelial Cells, Navneet Kaur
Nuclear Receptor Coactivator 3 in Endoplasmic Reticulum Stress and Stress Granule Dynamics in Pancreatic Cancer, Andrew Kisling
Molecular Mechanisms of Aberrant Protein Glycosylation in Pancreatic Cancer Stemness and Metastasis, Frank Leon
Mucin and Splice Variant Profiles of Pancreatic Adenocarcinoma Predict Patient Survival and Subtyping, Christopher M. Thompson
Theses/Dissertations from 2020
Deciphering the Catalytic Mechanism of Human Manganese Superoxide Dismutase, Jahaun Azadmanesh
The Role of the CXCR3 Signaling Axes in Pancreatic Ductal Adenocarcinoma, Andrew C. Cannon
Novel Detection and Treatment Strategies for Pancreatic Ductal Adenocarcinoma, Joseph Carmicheal
Novel regulatory roles of endocytic membrane trafficking proteins in mitochondrial homeostasis, Trey Farmer
Molecular Insights Into PAF-1 Mediated Pancreatic Homeostasis, Stemness, and Cancer Progression, Saswati Karmakar
Targeted Therapies in Select Gastrointestinal Cancers and Cancer Cachexia, Scott Mulder
Elucidating the role of Ecdysoneless in mRNA processing, Irfana Saleem
Molecular Mechanisms of Manganese Porphyrin Compounds in the Prevention of Radiation-Induced Fibrosis, Shashank Shrishrimal
Mechanisms by Which MnTE-2-PyP Suppresses Prostate Cancer Cell Growth, Yuxiang Zhu
Theses/Dissertations from 2019
Cholesterol Biosynthesis in the Nervous System with an Emphasis on Desmosterolosis, Luke Allen
Molecular Mechanisms Governing Muscle Wasting in Cancer, Aneesha Dasgupta
The Role of Reactive Oxygen Species in Regulating Macrophage and Fibroblast Activation Within the Breast Cancer Tumor Microenvironment, Brandon J. Griess
Developing Targeted Therapy against Pancreatic Cancer, Garima Kaushik
The Role of ROS in the Progression and Treatment of Castration-Resistant Prostate Cancer, Dannah R. Miller
Induction and metastasis of cancer stem cells in pancreatic cancer, Rama Krishna Nimmakayala
HDAC1 is a Required Cofactor of CBFβ-SMMHC and a Therapeutic Target in Inversion 16 Acute Myeloid Leukemia, Lisa E. Richter
Identification of Pathways Required for the Survival of Inversion(16) Acute Myeloid Leukemia, Yiqian Wang
Defining the Role of Tyrosine Phosphorylation in the Regulation of Connexin43 in Cardiac Diseases, Li Zheng
Theses/Dissertations from 2018
Inhibition of RAD52-based DNA repair for cancer therapy, Mona Al-Mugotir
MUC4 Based Immunotherapy for Pancreatic Cancer, Kasturi Banerjee
Connexin32: Sorting, Endocytosis and Assembly, Anuttoma Ray
Towards the Identification of the Molecular Mechanism Responsible for RPA:RAD52 Complex Formation, Lucas Struble
Intra- and Inter-Molecular Signaling in a Cardiac Connexin: Role of Cytoplasmic Domain Dimerization and Phosphorylation, Andrew J. Trease
Modulating Hallmarks of Cholangiocarcinoma, Cody Wehrkamp
The Beta-Catenin/MUC1.CT Interaction in Pancreatic Cancer, Edwin Wiest
Theses/Dissertations from 2017
Molecular mechanisms of C-terminal Eps15 Homology Domain containing (EHD) protein function, Kriti Bahl
Aberrant Glycosylation In Pancreatic Cancer Progression, Seema Chugh
Role of Endothelin Axis in Pancreatic Tumor Microenvironment, Suprit Gupta
Novel Therapeutic Strategies for Treatment of Castration-Resistant Prostate Cancer, Matthew A. Ingersoll
The Role of Semaphorin 5A in Pancreatic Cancer Progression and Metastasis, Sugandha Saxena Dr.
Basal and Experience Dependent Ampar and Synapse Dynamics: Alterations in a Mouse Model of Fragile X Syndrome, Anand Suresh
The Rise and Fall of the Bovine Corpus Luteum, Heather Talbott
Theses/Dissertations from 2016
Role of AKT2 in Cell Survival, Establishment and/or Maintenance of Colorectal Cancer Metastasis, Ekta Agarwal
Role of DDR1 in Pancreatic Cancer, Huocong Huang
Novel Regulatory Mechanisms and Functions of MUC4 in Pancreatic Cancer, Suhasini Joshi
Secretory Mucin MUC5AC in Gastrointestinal Malignancies, Shiv Ram Krishn
The role of oncogenic KRAS in initiation, progression and maintenance of pancreatic cancer, Nirakar Rajbhandari
The Mechanism of Tubular Recycling Endosome Biogenesis, Shuwei Xie
Exploitation of the Ligand-Binding Properties of the Mannose 6-Phosphate/Insulin-Like Growth Factor II (IGF-II) Receptor to Inhibit IGF-II-Dependent Growth of Cancer Cells, Megan Zavorka Thomas
Study of the Structure-Related Functions of Eukaryotic Primase-POL ALPHA Complex During Replication, Yinbo Zhang
Theses/Dissertations from 2015
Regulation of the transmembrane mucin MUC4 by Wnt/β-catenin in gastrointestinal cancers, Priya Pai
Regulatory roles of MICAL-L1 and EHD1 in cell signaling and mitosis, James B. Reinecke
Multifunctional role of pancreatic differentiation 2 (PD2) in pancreatic cancer, Arokia Priyanka Vaz
Theses/Dissertations from 2014
Mucin 16 (MUC16) in pancreatic cancer: expression and functional studies, Dhanya Haridas
The cytoplasmic tail of connexin232 in gap junction assembly, Parul Katoch
The role of Cbl and Cbl-b ubiquitin ligases in mammary gland development and mammary stem cell homeostasis, Bhopal Mohapatra
Role of Membrane Bund Mucins (MUC4, MUC16 and MUC17) in Gastro Intestinal (GI) Cancer, Das Srustidhar
Theses/Dissertations from 2013
Structural characterization of the connexin45 carboxyl-terminal domain and its interactions with molecular partners, Jennifer Lynn Kopanic
Functions of MICAL-family proteins in tubular recycling endosome biogenesis and cytoskeletal regulation, Sai Srinivas Panapakkam Giridharan
The role of mucins in the pathophysiology of pancreatic cancer with a focus on MUC7, Neeley Remmers
Theses/Dissertations from 2012
Roles of paired box 6 and its downstream genes in human pancreatic cancer, Mi Deng
Role of novel cell cycle regulator(s) in pancreatic cancer, Parama Dey
Regulation of ocular lens differentiation by protein sumoylation, Lili Gong
The role of DNA methyltransferases in cancer, Trevor D. Hedman
Endocytosis of connexin43 and gap junction assembly, Kristen E. Johnson
Smoking and pancreatic cancer, Navneet Momi
The structural insights to the mechanisms of EHD3 EH-domain binding with NPF-containing proteins, Calliste Reiling
Theses/Dissertations from 2011
Novel insights into the molecular diagnosis and therapy of pancreatic cancer, Subhankar Chakraborty
Role of transforming growth factor beta 1 in the regression of the corpus luteum, Dulce Maroni
Modulated crystals of profilin:actin, Jason Porta
Macromolecular therapy for improved treatment of rheumatoid arthritis, Lingdong Quan
The roles of Rab effectors and their interaction partners in endocytic trafficking, Juliati Rahajeng
Relaxin activates PPAR-gamma through a pathway involving CREB and PGC1alpha, Sudhir Singh
Theses/Dissertations from 2010
The role of cellular fibronectin in the promotion of alchohol, Razia S. Aziz-Seible
Identification and regulation of novel Sox2:Oct4 target genes in mouse embryonic stem (ES) cells, Harini Chakravarthy
Mannose 6-phosphate/insulin-like growth factor II receptor : multivalent ligand interactions and effects on IGF2-dependent growth, Christopher M. Connelly
Modulation of P53 oligomerization through differential phosphorylation of the MUC1 cytoplasmic tail, Samuel Joseph Erb
Ligand binding and ectodomain shedding of the mannose 6-phosphate/insulin-like growth factor II receptor, Michelle A. Montgomery
MUC4 and MUC17 membrane bound mucins : pathobiological implications in various cancers, Shantibhusan Senapati