Document Type

Article

Journal Title

Molecular and cellular biology

Publication Date

12-1986

Volume

6

Abstract

Alterations in prostatic acid phosphatase (PAcP), a phosphotyrosyl phosphatase, corresponded to changes in overall tyrosyl kinase activity. PAcP added to extracts of prostate carcinoma cells with a low endogenous level of PAcP activity and elevated tyrosyl kinase activity decreased the tyrosyl kinase activity. On the other hand, when PAcP activity was decreased by the addition of androgens to cells, there was a corresponding increase in tyrosyl kinase activity.

MeSH Headings

Acid Phosphatase, Cell Line, Humans, Kinetics, Male, Prostate, Prostatic Neoplasms, Protein-Tyrosine Kinases

ISSN

0270-7306

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