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Submissions from 2011

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Marital status and survival in pancreatic cancer patients: a SEER based analysis., Michael J. Baine, Freshta Sahak, Chi Lin, Subhankar Chakraborty, Surinder K. Batra, and Elizabeth R. Lyden

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Death receptor 5 signaling promotes hepatocyte lipoapoptosis., Sophie C. Cazanave, Justin L. Mott, Steven F. Bronk, Nathan W. Werneburg, Christian D. Fingas, X Wei Meng, Niklas Finnberg, Wafik S. El-Deiry, Scott H. Kaufmann, and Gregory J. Gores

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A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA., Sophie C. Cazanave, Justin L. Mott, Nafisa A. Elmi, Steven F. Bronk, Howard C. Masuoka, Michael R. Charlton, and Gregory J. Gores

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Progressive Multifocal Leukoencephalopathy in a HIV-Negative Patient with Small Lymphocytic Leukemia following Treatment with Rituximab., Subhankar Chakraborty, Stefano R. Tarantolo, John Treves, David Sambol, Ralph J. Hauke, and Surinder K. Batra

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Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells., Yu-Wei Chou, Nagendra K. Chaturvedi, Shougiang Ouyang, Fen-Fen Lin, Dharam Kaushik, Jue Wang, Isaac Kim, and Ming-Fong Lin

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Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancer., Parama Dey, Moorthy P. Ponnusamy, Shonali Deb, and Surinder K. Batra

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Cellular inhibitor of apoptosis 1 (cIAP-1) degradation by caspase 8 during TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis., Maria Eugenia Guicciardi, Justin L. Mott, Steven F. Bronk, Satoshi Kurita, Christian D. Fingas, and Gregory J. Gores

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Pathobiological implications of MUC16 expression in pancreatic cancer., Dhanya Haridas, Subhankar Chakraborty, Moorthy P. Ponnusamy, Imayavaramban Lakshmanan, Satyanarayana Rachagani, Eric Cruz, Sushil Kumar, Srustidhar Das, Subodh M. Lele, Judy M. Anderson, Uwe A. Wittel, Michael A. Hollingsworth, and Surinder K. Batra

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The Raf/MEK/extracellular signal-regulated kinase 1/2 pathway can mediate growth inhibitory and differentiation signaling via androgen receptor downregulation in prostate cancer cells., Seung-Keun Hong, Jin-Hwan Kim, Ming-Fong Lin, and Jong-In Park

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Monoclonal antibodies recognizing the non-tandem repeat regions of the human mucin MUC4 in pancreatic cancer., Maneesh Jain, Ganesh Venkatraman, Nicolas Moniaux, Sukhwinder Kaur, Sushil Kumar, Subhankar Chakraborty, Grish C. Varshney, and Surinder K. Batra

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Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination., Santosh Kumar, Satyendra Kumar, Mythilypriya Rajendran, Syed Mahfuzul Alam, Fen-Fen Lin, Pi-Wan Cheng, and Ming-Fong Lin

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Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells., Satoshi Kurita, Justin L. Mott, Sophie C. Cazanave, Christian D. Fingas, Maria E. Guicciardi, Steve F. Bronk, Lewis R. Roberts, Martin E. Fernandez-Zapico, and Gregory J. Gores

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Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy., Murielle Mimeault and Surinder K. Batra

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MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells., Moorthy P. Ponnusamy, Parthasarathy Seshacharyulu, Arokia P. Vaz, Parama Dey, and Surinder K. Batra

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Activated KrasG¹²D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin., Satyanarayana Rachagani, S Senapati, S Chakraborty, Moorthy P. Ponnusamy, Sushil Kumar, Lynette Smith, Maneesh Jain, and Surinder K. Batra

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TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands., Prakash Radhakrishnan, Vishwanath Chachadi, Ming-Fong Lin, Rakesh Singh, Reiji Kannagi, and Pi-Wan Cheng

Submissions from 2010

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Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis., Yuko Akazawa, Sophie Cazanave, Justin L. Mott, Nafisa Elmi, Steven F. Bronk, Shigeru Kohno, Michael R. Charlton, and Gregory J. Gores

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A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells., Christian D. Fingas, Boris R.A. Blechacz, Rory L. Smoot, Maria E. Guicciardi, Justin L. Mott, Steve F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica, and Gregory J. Gores

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Recent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies., Murielle Mimeault and Surinder K. Batra

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Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB., Justin L. Mott, Satoshi Kurita, Sophie C. Cazanave, Steven F. Bronk, Nathan W. Werneburg, and Martin E. Fernandez-Zapico

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p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis., Mythilypriya Rajendran, Paul Thomes, Li Zhang, Suresh Veeramani, and Ming-Fong Lin

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Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition., Ivette M. Sosa Seda, Justin L. Mott, Yuko Akazawa, Fernando J. Barreyro, Steven F. Bronk, Scott H. Kaufmann, and Gregory J. Gores

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MBP-1 upregulates miR-29b that represses Mcl-1, collagens, and matrix-metalloproteinase-2 in prostate cancer cells., Robert Steele, Justin L. Mott, and Ratna B. Ray

Submissions from 2009

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Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines., Yuko Akazawa, Justin L. Mott, Steven F. Bronk, Nathan W. Werneburg, Alisan Kahraman, Maria Eugenia Guicciardi, Xue Wei Meng, Shigeru Kohno, Vijay H. Shah, Scott H. Kaufmann, Mark A. McNiven, and Gregory J. Gores

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Pancreatic cancer cells resistance to gemcitabine: the role of MUC4 mucin., S. Bafna, Sukhwinder Kaur, N. Momi, and Surinder K. Batra

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JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis., Sophie C. Cazanave, Justin L. Mott, Nafisa A. Elmi, Steven F. Bronk, Nathan W. Werneburg, Yuko Akazawa, Alisan Kahraman, Sean P. Garrison, Gerard P. Zambetti, Michael R. Charlton, and Gregory J. Gores

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Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse., Alisan Kahraman, Steven F. Bronk, Sophie Cazanave, Nathan W. Werneburg, Justin L. Mott, Patricia C. Contreras, and Gregory J. Gores

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Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse., Alisan Kahraman, Justin L. Mott, Steven F. Bronk, Nathan W. Werneburg, Fernando J. Barreyro, Maria E. Guicciardi, Yuko Akazawa, Karen Braley, Ruth W. Craig, and Gregory J. Gores

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Mcl-1 degradation during hepatocyte lipoapoptosis., Howard C. Masuoka, Justin L. Mott, Steven F. Bronk, Nathan W. Werneburg, Yuko Akazawa, Scott H. Kaufmann, and Gregory J. Gores

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The human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression., Nicolas Moniaux, Christophe Nemos, Shonali Deb, Bing Zhu, Irena Dornreiter, Michael A. Hollingsworth, and Surinder K. Batra

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MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia., Justin L. Mott

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MicroRNAs: key modulators of posttranscriptional gene expression., Steven P. O'Hara, Justin L. Mott, Patrick L. Splinter, Gregory J. Gores, and Nicholas F. LaRusso

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Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis., Jianbing Qin, Yan Xie, Bo Wang, Mikio Hoshino, Dennis W. Wolff, Jing Zhao, Margaret A. Scofield, Frank J. Dowd, Ming-Fong Lin, and Yaping Tu

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Elevated expression of L-selectin ligand in lymph node-derived human prostate cancer cells correlates with increased tumorigenicity., Prakash Radhakrishnan, Ming-Fong Lin, and Pi-Wan Cheng

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Revisiting histidine-dependent acid phosphatases: a distinct group of tyrosine phosphatases., Suresh Veeramani, Ming-Shyue Lee, and Ming-Fong Lin

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Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer., Christine J. Ye, Joshua B. Stevens, Guo Liu, Steven W. Bremer, Aruna S. Jaiswal, Karen J. Ye, Ming-Fong Lin, Lesley Lawrenson, Wayne D. Lancaster, Markku Kurkinen, Joshua D. Liao, C. Gary Gairola, Malathy P. V. Shekhar, Satya Narayan, Fred R. Miller, and Henry H. Q. Heng

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Suppression of ErbB-2 in androgen-independent human prostate cancer cells enhances cytotoxic effect by gemcitabine in an androgen-reduced environment., Li Zhang, Jeffrey S. Davis, Stanislav Zelivianski, Fen-Fen Lin, Rachel Schutte, Thomas L. Davis, Ralph Hauke, Surinder K. Batra, and Ming-Fong Lin

Submissions from 2008

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Androgen-independent prostate cancer cells acquire the complete steroidogenic potential of synthesizing testosterone from cholesterol., Paulette R. Dillard, Ming-Fong Lin, and Shafiq A. Khan

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TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse., Alisan Kahraman, Fernando J. Barreyro, Steven F. Bronk, Nathan W. Werneburg, Justin L. Mott, Yuko Akazawa, Howard C Masuoka, Charles L Howe, and Gregory J. Gores

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MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer., W. R. Matull, F. Andreola, A. Loh, Z. Adiguzel, M. Deheragoda, U. Qureshi, Surinder K. Batra, D. M. Swallow, and S. P. Pereira

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Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia., N. Moniaux, S. Chakraborty, M. Yalniz, J. Gonzalez, Valerie K. Shostrom, J. Standop, Subodh M. Lele, Michel M. Ouellette, Parviz M. Pour, Aaron Sasson, R. E. Brand, Michael A. Hollingsworth, Maneesh Jain, and Surinder K. Batra

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BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis., Justin L. Mott, Steve F. Bronk, Ruben A. Mesa, Scott H. Kaufmann, and Gregory J. Gores

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Ovarian cancer: emerging concept on cancer stem cells., Moorthy P. Ponnusamy and Surinder K. Batra

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MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells., Moorthy P. Ponnusamy, A. P. Singh, Maneesh Jain, S. Chakraborty, N. Moniaux, and Surinder K. Batra

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Deregulation of MUC4 in gastric adenocarcinoma: potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer., S. Senapati, P. Chaturvedi, P. Sharma, G Venkatraman, Jane L. Meza, W. El-Rifai, H. K. Roy, and Surinder K. Batra

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Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells., Ajay P. Singh, Sangeeta Bafna, Kunal Chaudhary, Ganesh Venkatraman, Lynette Smith, James D. Eudy, Sonny L. Johansson, Ming-Fong Lin, and Surinder K. Batra

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Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells., Suresh Veeramani, Ta-Chun Yuan, Fen-Fen Lin, and Ming-Fong Lin

Submissions from 2007

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Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing., Hajime Isomoto, Justin L. Mott, Shogo Kobayashi, Nathan W. Werneburg, Steve F. Bronk, Serge Haan, and Gregory J. Gores

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Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers., M. Mimeault, Ralph Hauke, Parmender P. Mehta, and Surinder K. Batra

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Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells., N. Moniaux, P. Chaturvedi, G. C. Varshney, Jane L. Meza, J. F. Rodriguez-Sierra, J-P Aubert, and Surinder K. Batra

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mir-29 regulates Mcl-1 protein expression and apoptosis., Justin L. Mott, Shogo Kobayashi, Steven F. Bronk, and Gregory J. Gores

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An essential role of human Ada3 in p53 acetylation., Alo Nag, Aleksandra Germaniuk-Kurowska, Manjari Dimri, Michael A. Sassack, Channabasavaiah B. Gurumurthy, Qingshen Gao, Goberdhan Dimri, Hamid Band, and Vimla Band

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The notch regulator MAML1 interacts with p53 and functions as a coactivator., Yongtong Zhao, Rebecca B. Katzman, Laurie M. Delmolino, Ishfaq Bhat, Ying Zhang, Channabasavaiah B. Gurumurthy, Aleksandra Germaniuk-Kurowska, Honey V. Reddi, Aharon Solomon, Mu-Sheng Zeng, Aisha Kung, Hui Ma, Qingshen Gao, Goberdhan Dimri, Adina Stanculescu, Lucio Miele, Lizi Wu, James D. Griffin, David E. Wazer, Hamid Band, and Vimla Band

Submissions from 2006

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Androgen-regulated formation and degradation of gap junctions in androgen-responsive human prostate cancer cells., Shalini Mitra, Lakshmanan Annamalai, Souvik Chakraborty, Kristen E. Johnson, Xiao-Hong Song, Surinder K. Batra, and Parmender P. Mehta

Submissions from 2005

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Mitochondrial DNA mutations, apoptosis, and the misfolded protein response., Justin L. Mott, Dekui Zhang, and Hans Peter Zassenhaus

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The human PAF complex coordinates transcription with events downstream of RNA synthesis., Bing Zhu, Subhrangsu S. Mandal, Anh-Dung Pham, Yong Zheng, Hediye Erdjument-Bromage, Surinder K. Batra, Paul Tempst, and Danny Reinberg

Submissions from 2004

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MUC4 mucin expression in human pancreatic tumours is affected by organ environment: the possible role of TGFbeta2., A. Choudhury, N. Moniaux, A. B. Ulrich, B. M. Schmied, J. Standop, Parviz M. Pour, S. J. Gendler, Michael A. Hollingsworth, J-P Aubert, and Surinder K. Batra

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Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy., N. Moniaux, M. Andrianifahanana, R. E. Brand, and Surinder K. Batra

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Transcriptional activation of the human prostatic acid phosphatase gene by NF-kappaB via a novel hexanucleotide-binding site., Stanislav Zelivianski, Richard Glowacki, and Ming-Fong Lin

Submissions from 2001

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Expression of tumor-associated glycoprotein-72 (TAG-72) antigen in human prostatic adenocarcinomas., Dev Karan, Sonny L. Johansson, Ming-Fong Lin, and Surinder K. Batra

Submissions from 2000

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Genomic structure of murine mitochondrial DNA polymerase-gamma., Justin L. Mott, Grace Denniger, Steve J. Zullo, and H. Peter Zassenhaus

Submissions from 1988

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The epidermal growth factor receptor from prostate cells is dephosphorylated by a prostate-specific phosphotyrosyl phosphatase., Ming-Fong Lin and Gail M. Clinton

Submissions from 1987

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Developmental expression of tyrosyl kinase activity in human serum., Ming-Fong Lin, Joan E. Bailey-Wilson, Robert C. Elston, and Gail M. Clinton

Submissions from 1986

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Tyrosyl kinase activity is inversely related to prostatic acid phosphatase activity in two human prostate carcinoma cell lines., Ming-Fong Lin, Ching-Li Lee, and Gail M. Clinton