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Submissions from 2017

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Novel long-chain compounds with both immunomodulatory and MenA inhibitory activities against Staphylococcus aureus and its biofilm., Seoung-Ryoung Choi, Joel Frandsen, and Prabagaran Narayanasamy

Submissions from 2016

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Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis., Ryan D. Geraets, Seung yon Koh, Michelle L. Hastings, Tammy Kielian, David A. Pearce, and Jill M. Weimer

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IL-10 plays an important role in the control of inflammation but not in the bacterial burden in S. epidermidis CNS catheter infection., Yenis M. Gutierrez-Murgas, Gwenn Skar, Danielle Ramirez, Matthew Beaver, and Jessica N. Snowden

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Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-αβ Structure., Judy T.Y. Lee, Guangshun Wang, Yu Tong Tam, and Connie Tam

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Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia., Keer Sun, Vijaya Kumar Yajjala, Christopher Bauer, G. Talmon, Karl J. Fischer, Tammy Kielian, and Dennis W. Metzger

Submissions from 2015

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Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy., Wei An, Scott A. Nadeau, Bhopal C. Mohapatra, Dan Feng, Neha Zutshi, Matthew D. Storck, Priyanka Arya, James E. Talmadge, Jane L. Meza, Vimla Band, and Hamid Band

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Neuroinflammatory paradigms in lysosomal storage diseases., Megan Bosch and Tammy Kielian

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Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma., Ning Ding, Xitao Li, Yunfei Shi, Lingyan Ping, Lina Wu, Kai Fu, Lixia Feng, Xiaohui Zheng, Yuqin Song, Zhengying Pan, and Jun Zhu

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Primary sclerosing epithelioid fibrosarcoma of kidney with variant histomorphologic features: report of 2 cases and review of the literature., Dilek Ertoy Baydar, Kemal Kosemehmetoglu, Oguz Aydin, Julia A. Bridge, Berrin Buyukeren, and Fazil Tuncay Aki

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Prolonged-acting, multi-targeting gallium nanoparticles potently inhibit growth of both HIV and mycobacteria in co-infected human macrophages., Prabagaran Narayanasamy, Barbara L. Switzer, and Bradley E. Britigan

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Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin., Tyler D. Scherr, Mark L. Hanke, Ouwen Huang, David B.A. James, Alexander R. Horswill, Kenneth W. Bayles, Paul D. Fey, Victor J. Torres, and Tammy Kielian

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Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses., Shweta Tripathi, Guangshun Wang, Mitchell White, Li Qi, Jeffery Taubenberger, and Kevan L. Hartshorn

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Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis., Shweta Tripathi, Guangshun Wang, Mitchell White, Michael Rynkiewicz, Barbara Seaton, and Kevan Hartshorn

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Antimicrobial Peptides in 2014., Guangshun Wang, Biswajit Mishra, Kyle Lau, Tamara Lushnikova, Radha Golla, and Xiuqing Wang

Submissions from 2014

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Hemichannels in neurodegenerative diseases: is there a link to pathology?, Megan Bosch and Tammy Kielian

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Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)., Maria Burkovetskaya, Nikolay Karpuk, Juan Xiong, Megan Bosch, Michael D. Boska, Hideyuki Takeuchi, Akio Suzumura, and Tammy Kielian

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A central role for carbon-overflow pathways in the modulation of bacterial cell death., Vinai Chittezham Thomas, Marat Sadykov, Sujata S. Chaudhari, Joselyn Jones, Jennifer L. Endres, Todd J. Widhelm, Jong-Sam Ahn, Randeep S. Jawa, Matthew C. Zimmerman, and Kenneth W. Bayles

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Classification of current anticancer immunotherapies., Lorenzo Galluzzi, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, and Guido Kroemer

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Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness., Mohammad-Saeid Jami, Jinxuan Hou, Miao Liu, M L. Varney, Hesham Hassan, Jixin Dong, Liying Geng, J. Wang, Fang Yu, Xin Huang, Hong Peng, Kai Fu, Yan Li, Rakesh Singh, and Shi-Jian Ding

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Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group., Michael J. Monument, Kirsten M. Johnson, Elizabeth McIlvaine, Lisa Abegglen, W. Scott Watkins, Lynn B. Jorde, Richard B. Womer, Natalie Beeler, Laura Monovich, Elizabeth R. Lawlor, Julia A. Bridge, Joshua D. Schiffman, Mark D Krailo, R. Lor Randall, and Stephen L. Lessnick

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Temporal and stochastic control of Staphylococcus aureus biofilm development., Derek E. Moormeier, Jeffrey L. Bose, Alexander R. Horswill, and Kenneth W. Bayles

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Response of an aggressive periosteal aneurysmal bone cyst (ABC) of the radius to denosumab therapy., Chantal Pauli, Bruno Fuchs, Christian Pfirrmann, Julia A. Bridge, Silvia Hofer, and Beata Bode

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Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity., Tyler D. Scherr, Cortney E. Heim, John M. Morrison, and Tammy Kielian

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Expression of suppressor of cytokine signaling 1 (SOCS1) impairs viral clearance and exacerbates lung injury during influenza infection., Keer Sun, Sharon Salmon, Vijaya Kumar Yajjala, Christopher Bauer, and Dennis W. Metzger

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Human Antimicrobial Peptides and Proteins, Guangshun Wang

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Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds., Guangshun Wang, Mark L. Hanke, Biswajit Mishra, Tamara Lushnikova, Cortney E. Heim, Vinai Chittezham Thomas, Kenneth W. Bayles, and Tammy Kielian

Submissions from 2013

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A dysfunctional tricarboxylic acid cycle enhances fitness of Staphylococcus epidermidis during β-lactam stress., Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, and Paul D. Fey

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A genetic resource for rapid and comprehensive phenotype screening of nonessential Staphylococcus aureus genes., Paul D. Fey, Jennifer L. Endres, Vijaya Kumar Yajjala, Todd J. Widhelm, Robert J. Boissy, Jeffrey L. Bose, and Kenneth W. Bayles

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Database-Guided Discovery of Potent Peptides to Combat HIV-1 or Superbugs., Guangshun Wang

Submissions from 2012

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Contribution of the Staphylococcus aureus Atl AM and GL murein hydrolase activities in cell division, autolysis, and biofilm formation., Jeffrey L. Bose, McKenzie K. Lehman, Paul D. Fey, and Kenneth W. Bayles

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MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection., Mark L. Hanke, Amanda Angle, and Tammy Kielian

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Deciphering mechanisms of staphylococcal biofilm evasion of host immunity., Mark L. Hanke and Tammy Kielian

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Low levels of β-lactam antibiotics induce extracellular DNA release and biofilm formation in Staphylococcus aureus., Jeffrey B. Kaplan, Era A. Izano, Prerna Gopal, Michael T. Karwacki, Sangho Kim, Jeffrey L. Bose, Kenneth W. Bayles, and Alexander R. Horswill

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The Importance of Amino Acid Composition in Natural AMPs: An Evolutional, Structural, and Functional Perspective., Biswajit Mishra and Guangshun Wang

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CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism., Austin S. Nuxoll, Steven M. Halouska, Marat Sadykov, Mark L. Hanke, Kenneth W. Bayles, Tammy Kielian, Robert Powers, and Paul D. Fey

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Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection., Debbie Vidlak and Tammy Kielian

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IL-1RI (interleukin-1 receptor type I) signalling is essential for host defence and hemichannel activity during acute central nervous system bacterial infection., Juan Xiong, Maria Burkovetskaya, Nikolay Karpuk, and Tammy Kielian

Submissions from 2011

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Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274., Jinxuan Hou, Jixin Dong, Lijun Sun, Liying Geng, J. Wang, Jialin C. Zheng, Yan Li, Julia A. Bridge, Steven H. Hinrichs, and Shi-Jian Ding

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Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity., Nikolay Karpuk, Maria Burkovetskaya, Teresa Fritz, Amanda Angle, and Tammy Kielian

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Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus., Megan R. Kiedrowski, Jeffrey S. Kavanaugh, Cheryl L. Malone, Joe M. Mootz, Jovanka M. Voyich, Mark S. Smeltzer, Kenneth W. Bayles, and Alexander R. Horswill

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MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection., Shuliang Liu and Tammy Kielian

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Major families of multiresistant plasmids from geographically and epidemiologically diverse staphylococci., Julia E.S. Shearer, Joy Wireman, Jessica Hostetler, Heather Forberger, Jon Borman, John Gill, Susan Sanchez, Alexander Mankin, Jacqueline Lamarre, Jodi A. Lindsay, Kenneth W. Bayles, Ainsley Nicholson, Frances O'Brien, Slade O. Jensen, Neville Firth, Ronald A. Skurray, and Anne O. Summers

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De Novo Design of Antiviral and Antibacterial Peptides with Varying Loop Structures, Guangshun Wang, Karen W. Buckheit, Biswajit Mishra, Tamara Lushnikova, and Robert W. Buckheit Jr.

Submissions from 2010

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Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation., Karen E. Beenken, Lara N. Mrak, Linda M. Griffin, Agnieszka K. Zielinska, Lindsey N. Shaw, Kelly C. Rice, Alexander R. Horswill, Kenneth W. Bayles, and Mark S. Smeltzer

Submissions from 2009

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MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses., Sarita Garg, Jessica R. Nichols, Nilufer Esen, Shuliang Liu, Nirmal K. Phulwani, Mohsin Md. Syed, William H. Wood, Yongqing Zhang, Kevin G. Becker, Amy Aldrich, and Tammy Kielian

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Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus., Xianglu Li, William G. Fusco, Keun S. Seo, Kenneth W. Bayles, Erin E. Mosley, Mark A. McGuire, and Gregory A. Bohach

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Assembly and development of the Pseudomonas aeruginosa biofilm matrix., Luyan Ma, Matthew Conover, Haiping Lu, Matthew R. Parsek, Kenneth W. Bayles, and Daniel J. Wozniak

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Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation., Ethan E. Mann, Kelly C. Rice, Blaise R. Boles, Jennifer L. Endres, Dev Ranjit, Lakshmi Chandramohan, Laura H. Tsang, Mark S. Smeltzer, Alexander R. Horswill, and Kenneth W. Bayles

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SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype., Ana Mozos, Cristina Royo, Elena Hartmann, Daphne De Jong, Cristina Baró, Alexandra Valera, Kai Fu, Dennis D. Weisenburger, Jan Delabie, Shih-Sung Chuang, Elaine S. Jaffe, Carmen Ruiz-Marcellan, Sandeep Dave, Lisa Rimsza, Rita Braziel, Randy D. Gascoyne, Francisco Solé, Armando López-Guillermo, Dolors Colomer, Louis M. Staudt, Andreas Rosenwald, German Ott, Pedro Jares, and Elias Campo

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APD2: the updated antimicrobial peptide database and its application in peptide design., Guangshun Wang, Xia Li, and Zhe Wang

Submissions from 2008

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Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-gamma Agonists., Catherine Gurley, Jessica Nichols, Shuliang Liu, Nirmal K. Phulwani, Nilufer Esen, and Tammy Kielian

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Stromal gene signatures in large-B-cell lymphomas., G Lenz, G Wright, S S Dave, W Xiao, J Powell, H Zhao, W Xu, B Tan, N Goldschmidt, Javeed Iqbal, Julie M. Vose, M Bast, Kai Fu, D D. Weisenburger, T C Greiner, James O. Armitage, A Kyle, L May, R D Gascoyne, J M Connors, G Troen, H Holte, S Kvaloy, D Dierickx, G Verhoef, J Delabie, E B Smeland, P Jares, A Martinez, A Lopez-Guillermo, E Montserrat, E Campo, R M Braziel, T P Miller, L M Rimsza, J R Cook, B Pohlman, J Sweetenham, R R Tubbs, R I Fisher, E Hartmann, A Rosenwald, G Ott, H-K Muller-Hermelink, D Wrench, T A Lister, E S Jaffe, W H Wilson, W C. Chan, and L M Staudt

Submissions from 2007

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Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs)., Nilufer Esen and Tammy Kielian

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Clinical implication of genome-wide profiling in diffuse large B-cell lymphoma and other subtypes of B-cell lymphoma., Javeed Iqbal, Shantaram Joshi, Kavita N. Patel, Sofi I. Javed, Can Kucuk, Afeera Aabida, Francesco d'Amore, and Kai Fu

Submissions from 2006

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Molecular diagnosis of Burkitt's lymphoma., Sandeep S. Dave, Kai Fu, George W. Wright, Lloyd T. Lam, Philip Kluin, Evert-Jan Boerma, Timothy Greiner, Dennis D. Weisenburger, Andreas Rosenwald, German Ott, Hans-Konrad Müller-Hermelink, Randy D. Gascoyne, Jan Delabie, Lisa M. Rimsza, Rita M. Braziel, Thomas M. Grogan, Elias Campo, Elaine S. Jaffe, Bhavana J. Dave, Warren Sanger, M Bast, Julie M. Vose, James O. Armitage, Joseph M. Connors, Erlend B. Smeland, Stein Kvaloy, Harald Holte, Richard I. Fisher, Thomas P. Miller, Emilio Montserrat, Wyndham H. Wilson, Manisha Bahl, Hong Zhao, Liming Yang, John Powell, Richard Simon, Wing C. Chan, and Louis M. Staudt

Submissions from 2004

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Immunopathogenesis of brain abscess., Tammy Kielian

Submissions from 1996

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Analysis of the effects of overexpression of metallothionein-I in transgenic mice on the reproductive toxicology of cadmium., T Dalton, Kai Fu, G C Enders, R D Palmiter, and G K Andrews