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Submissions from 2022

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Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism, Bhopal C. Mohapatra, Sameer Mirza, Aditya Bele, Channabasavaiah B. Gurumurthy, Mohsin Raza, Irfana Saleem, Matthew D. Storck, Aniruddha Sarkar, Sai Sundeep Kollala, Surendra K. Shukla, Siddesh Southekal, Kay-Uwe Wagner, Fang Qiu, Subodh M. Lele, Mansour A. Alsaleem, Emad A. Rakha, Chittibabu Guda, Pankaj K. Singh, Robert D. Cardiff, Hamid Band, and Vimla Band

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CRISPR-KRISPR: A Method to Identify On-Target and Random Insertion of Donor DNAs and their Characterization in Knock-In Mice, Masayuki Tanaka, Keiko Yokoyama, Hideki Hayashi, Sanae Isaki, Kanae Kitatani, Ting Wang, Hisako Kawata, Hideyuki Matsuzawa, Channabasavaiah B. Gurumurthy, Hiromi Miura, and Masato Ohtsuka

Submissions from 2021

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Response to correspondence on "Reproducibility of CRISPR-Cas9 Methods for Generation of Conditional Mouse Alleles: A Multi-Center Evaluation", Channabasavaiah B. Gurumurthy, Aidan R. O'Brien, Rolen M. Quadros, John Adams, Pilar Alcaide, Shinya Ayabe, Johnathan Ballard, Surinder K. Batra, Marie-Claude Beauchamp, Kathleen A. Becker, Guillaume Bernas, David Brough, Francisco Carrillo-Salinas, Wesley Chan, Hanying Chen, Ruby Dawson, Victoria DeMambro, Jinke D'Hont, Katharine Dibb, James D. Eudy, Lin Gan, Jing Gao, Amy Gonzales, Anyonya Guntur, Huiping Guo, Donald W. Harms, Anne Harrington, Kathryn E. Hentges, Neil Humphreys, Shiho Imai, Hideshi Ishii, Mizuho Iwama, Eric Jonasch, Michelle Karolak, Bernard Keavney, Nay-Chi Khin, Masamitsu Konno, Yuko Kotani, Yayoi Kunihiro, Imayavaramban Lakshmanan, Catherine Larochelle, Catherine B. Lawrence, Lin Li, Volkhard Lindner, Xian-De Liu, Gloria Lopez-Castejon, Andrew Loudon, Jenna Lowe, Loydie Jerome-Majeweska, Taiji Matsusaka, Hiromi Miura, Yoshiki Miyasaka, Benjamin Morpurgo, Katherine Motyl, Yo-Ichi Nabeshima, Koji Nakade, Toshiaki Nakashiba, Kenichi Nakashima, Yuichi Obata, Sanae Ogiwara, Mariette Ouellet, Leif Oxburgh, Sandra Piltz, Ilka Pinz, Moorthy P. Ponnusamy, David Ray, Ronald J. Redder, Clifford J. Rosen, Nikki Ross, Mark T. Ruhe, Larisa Ryzhova, Ane M. Salvador, Sabrina Shameen Alam, Radislav Sedlacek, Karan Sharma, Chad Smith, Katrien Staes, Lora Starrs, Fumihiro Sugiyama, Satoru Takahashi, Tomohiro Tanaka, Andrew Trafford, Yoshihiro Uno, Leen Vanhoutte, Frederique Vanrockeghem, Brandon J. Willis, Christian S. Wright, Yuko Yamauchi, Xin Yi, Kazuto Yoshimi, Xuesong Zhang, Yu Zhang, Masato Ohtsuka, Satyabrata Das, Daniel J. Garry, Tino Hochepied, Paul Thomas, Jan Parker-Thornburg, Antony D. Adamson, Atsushi Yoshiki, Jean-Francois Schmouth, Andrei Golovko, William R. Thompson, K C Kent Lloyd, Joshua A. Wood, Mitra Cowan, Tomoji Mashimo, Seiya Mizuno, Hao Zhu, Petr Kasparek, Lucy Liaw, Joseph M. Miano, and Gaetan Burgio

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CD4+ Effector T cells Accelerate Alzheimer's Disease in Mice, Jatin Machhi, Pravin Yeapuri, Yaman Lu, Emma Foster, Rupesh Chikhale, Jonathan Herskovitz, Krista L. Namminga, Katherine E. Olson, Mai Mohamed Abdelmoaty, Ju Gao, Rolen M. Quadros, Tomomi Kiyota, Liang Jingjing, Bhavesh D. Kevadiya, Xinglong Wang, Yutong Liu, Larisa Y. Poluektova, Channabasavaiah B. Gurumurthy, R. Lee Mosley, and Howard Gendelman

Submissions from 2020

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Engineered Extracellular Vesicles Loaded With miR-124 Attenuate Cocaine-Mediated Activation of Microglia, Ernest T. Chivero, Ke Liao, Fang Niu, Ashutosh Tripathi, Changhai Tian, Shilpa Buch, and Guoku Hu

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A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues., Amy T Desaulniers, Rebecca A Cederberg, Elizabeth P Carreiro, Channabasavaiah B Gurumurthy, and Brett R White

Submissions from 2019

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Ca2+ Sensor Synaptotagmin-1 Mediates Exocytosis in Mammalian Photoreceptors, Justin J. Grassmeyer, Asia L. Cahill, Cassandra L. Hays, Cody Barta, Rolen M. Quadros, Channabasavaiah B. Gurumurthy, and Wallace B. Thoreson

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A Synthetic Agonist to Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities in Models of Parkinson's Disease, R. Lee Mosley, Yaman Lu, Katherine E. Olson, Jatin Machhi, Wenhui Yan, Krista L. Namminga, Jenell R. Smith, Scott J. Shandler, and Howard Gendelman

Submissions from 2018

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MicroRNA Cluster miR199a/214 are Differentially Expressed in Female and Male Rats Following Nicotine Self-Administration, Steven T. Pittenger, Victoria L. Schaal, Dalia Moore, Rahul S. Guda, Sneh Koul, Sowmya V. Yelamanchili, Rick A. Bevins, and Gurudutt Pendyala

Submissions from 2017

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A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy., Mariluz Araínga, Benson J. Edagwa, R. Lee Mosley, Larisa Y. Poluektova, Santhi Gorantla, and Howard Gendelman

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Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus-Insights in pathogenesis and perspectives for new treatments., Sara Hägglund, Krister Blodörn, Katarina Näslund, Karin Vargmar, Sara Bergström Lind, Jia Mi, Mariluz Araínga, Sabine Riffault, Geraldine Taylor, John Pringle, and Jean François Valarcher

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Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect., Emily Harrison, Kathleen M. Emanuel, Benjamin G. Lamberty, Brenda M. Morsey, Min Li, Matthew L. Kelso, Sowmya V. Yelamanchili, and Howard S. Fox

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Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration., Yuju Li, Justin Peer, Runze Zhao, Yinghua Xu, Beiqing Wu, Yi Wang, Changhai Tian, Yunlong Huang, and Jialin C. Zheng

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Kiss-and-Run Is a Significant Contributor to Synaptic Exocytosis and Endocytosis in Photoreceptors., Xiangyi Wen, Grant W. Saltzgaber, and Wallace B. Thoreson

Submissions from 2016

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HIV-1 cellular and tissue replication patterns in infected humanized mice., Mariluz Araínga, Hang Su, Larisa Y Poluektova, Santhi Gorantla, and Howard Gendelman

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HIV-1 cellular and tissue replication patterns in infected humanized mice., Mariluz Araínga, Hang Su, Larisa Y Poluektova, Santhi Gorantla, and Howard Gendelman

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Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation, Emily B. Harrison, Colleen G. Hochfelder, Benjamin G. Lamberty, Brittney M. Meays, Brenda M. Morsey, Matthew L. Kelso, Howard S. Fox, and Sowmya V. Yelamanchili

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Metabolic drift in the aging brain., Julijana Ivanisevic, Kelly L. Stauch, Michael Petrascheck, H. Paul Benton, Adrian A. Epstein, Mingliang Fang, Santhi Gorantla, Minerva Tran, Linh Hoang, Michael E. Kurczy, Michael D. Boska, Howard Gendelman, Howard S. Fox, and Gary Siuzdak

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A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis., Meripet Polat, Shin-Nosuke Takeshima, Kazuyoshi Hosomichi, Jiyun Kim, Taku Miyasaka, Kazunori Yamada, Mariluz Araínga, Tomoyuki Murakami, Yuki Matsumoto, Veronica de la Barra Diaz, Carlos Javier Panei, Ester Teresa González, Misao Kanemaki, Misao Onuma, Guillermo Giovambattista, and Yoko Aida

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A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis., Meripet Polat, Shin-Nosuke Takeshima, Kazuyoshi Hosomichi, Jiyun Kim, Taku Miyasaka, Kazunori Yamada, Mariluz Araínga, Tomoyuki Murakami, Yuki Matsumoto, Veronica de la Barra Diaz, Carlos J. Panei, Ester T. González, Misao Kanemaki, Misao Onuma, Guillermo Giovambattista, and Yoko Aida

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The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy., Gang Zhang, Dongwei Guo, Prasanta Dash, Mariluz Araínga, Jayme Wiederin, Nicole A. Haverland, Jaclyn Knibbe-Hollinger, Andrea Martinez-Skinner, Pawel Ciborowski, Val S. Goodfellow, Tadeusz A. Wysocki, Beata J. Wysocki, Larisa Y. Poluektova, Xin-Ming Liu, JoEllyn McMillan, Santhi Gorantla, Harris A. Gelbard, and Howard Gendelman

Submissions from 2015

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Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages., Mariluz Araínga, Dongwei Guo, Jayme Wiederin, Pawel Ciborowski, JoEllyn McMillan, and Howard Gendelman

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Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages., Mariluz Araínga, Dongwei Guo, Jayme Wiederin, Pawel Ciborowski, JoEllyn McMillan, and Howard Gendelman

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Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment., Siqiang Lai, Min Zhang, Dongsheng Xu, Yiying Zhang, Lisha Qiu, Changhai Tian, and Jialin Charlie Zheng

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Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy., Tianyuzi Li, Howard Gendelman, Gang Zhang, Pavan Puligujja, JoEllyn McMillan, Tatiana K. Bronich, Benson Edagwa, Xin-Ming Liu, and Michael D. Boska

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Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy., Andrea L. Martinez-Skinner, Mariluz Araínga, Pavan Puligujja, Diana L. Palandri, Hannah M. Baldridge, Benson J. Edagwa, JoEllyn McMillan, R. Lee Mosley, and Howard Gendelman

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Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy., Andrea L. Martinez-Skinner, Mariluz Araínga, Pavan Puligujja, Diana L. Palandri, Hannah M. Baldridge, Benson J. Edagwa, JoEllyn McMillan, R. Lee Mosley, and Howard Gendelman

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Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice., Katherine E. Olson, Lisa M. Kosloski-Bilek, Kristi M. Anderson, Breha J. Diggs, Barbara E. Clark, John M. Gledhill, Scott J. Shandler, R. Lee Mosley, and Howard Gendelman

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Pharmacodynamics of folic acid receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice., Pavan Puligujja, Mariluz Araínga, Prasanta Dash, Diana L. Palandri, R. Lee Mosley, Santhi Gorantla, Larisa Y Poluektova, JoEllyn McMillan, and Howard Gendelman

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Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion., Changhai Tian, Yuju Li, Yunlong Huang, Yongxiang Wang, Dapeng Chen, Jinxu Liu, Xiaobei Deng, Lijun Sun, Kristi Anderson, Xinrui Qi, Yulong Li, R. Lee Mosley, Xiangmei Chen, Jian Huang, and Jialin C. Zheng

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MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease., Sowmya V. Yelamanchili, Benjamin G. Lamberty, Deborah A. Rennard, Brenda M. Morsey, Colleen G. Hochfelder, Brittney M. Meays, Efrat Levy, and Howard S. Fox

Submissions from 2014

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Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders., Kristi M. Anderson, Katherine E. Olson, Katherine A. Estes, Ken Flanagan, Howard E. Gendelman, and R. Lee Mosley

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Intracellular calcium stores drive slow non-ribbon vesicle release from rod photoreceptors, Minghui Chen, David Križaj, and Wallace B. Thoreson

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Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes., Benson J. Edagwa, Dongwei Guo, Pavan Puligujja, Han Chen, JoEllyn McMillan, Xinming Liu, Howard Gendelman, and Prabagaran Narayanasamy

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Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors., Matthew J. Van Hook, Caitlyn M. Parmelee, Minghui Chen, Karlene M. Cork, Carina Curto, and Wallace B. Thoreson

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The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins., Sowmya V. Yelamanchili, Brenda M. Morsey, Emily B. Harrison, D. A. Rennard, Kathleen M. Emanuel, I Thapa, D. R. Bastola, and H. S. Fox

Submissions from 2013

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Properties of ribbon and non-ribbon release from rod photoreceptors revealed by visualizing individual synaptic vesicles., Minghui Chen, Matthew J. Van Hook, David Zenisek, and Wallace B. Thoreson

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Combined fluorescent in situ hybridization for detection of microRNAs and immunofluorescent labeling for cell-type markers, Amrita Datta Chaudhuri, Sowmya V. Yelamanchili, and Howard S. Fox

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MicroRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1, Amrita Datta Chaudhuri, Sowmya V. Yelamanchili, and Howard S. Fox

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Anticuerpos contra el virus de la parainfluenza 3 en cerdos de crianza tecnificada y de traspatio beneficiados en mataderos de Lima, Milagros P. Montesinos, Hermelinda G. Rivera, and Mariluz Araínga

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Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors., Changhai Tian, Qiang Liu, Kangmu Ma, Yongxiang Wang, Qiang Chen, Randall Ambroz, David L. Klinkebiel, Yuju Li, Yunlong Huang, Jianqing Ding, Jie Wu, and Jialin C. Zheng

Submissions from 2012

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Frecuencia de leptospira spp en porcinos de crianza tecnificada y de traspatio beneficiados en dos mataderos de lima, Luis Anampa V., Hermelinda Rivera G., Nestor Falcon P., Mariluz Araínga, and Mercy Ramirez V.

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Visualizing spatiotemporal dynamics of apoptosis after G1 arrest by human T cell leukemia virus type 1 Tax and insights into gene expression changes using microarray-based gene expression analysis., Mariluz Araínga, Hironobu Murakami, and Yoko Aida

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Identification of bovine leukemia virus tax function associated with host cell transcription, signaling, stress response and immune response pathway by microarray-based gene expression analysis., Mariluz Araínga, Eri Takeda, and Yoko Aida

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Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated neuronal dysfunction., Guoku Hu, H Yao, A D. Chaudhuri, Sowmya V. Yelamanchili, H Wen, P D. Cheney, Howard S. Fox, and Shilpa J. Buch

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Seroprevalencia de pestivirus de rumiantes en ovinos reproductores de una empresa de la sierra central del Perú, Nathalie A. Llancares, Hermelinda G. Rivera, Mariluz Araínga, and Nestor Falcon P.

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Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders., Lixia Zhao, Yunlong Huang, Changhai Tian, Lynn Taylor, Norman Curthoys, Yi Wang, Hamilton Vernon, and Jialin C. Zheng

Submissions from 2011

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Prevalencia del virus de la diarrea viral bovina y de animales portadores del virus en bovinos en la provincia de Espinar, Cusco., Cesar Cardenas A., Hermelinda G. Rivera, Mariluz Araínga, Mercy Ramirez V., and Jimmy De Paz M.

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Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism., Sowmya V. Yelamanchili, Amrita Datta Chaudhuri, Claudia T. Flynn, and Howard S. Fox

Submissions from 2010

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Fenotipo y genotipo del virus de la diarrea viral aislado de bovinos en el Perú., Mariluz Araínga, Hermelinda Rivera G., Juan Carlos Huaman G., and Alberto Manchego S.

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MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease., Sowmya V. Yelamanchili, A Datta Chaudhuri, L N. Chen, Huangui Xiong, and Howard S. Fox

Submissions from 2009

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Persistencia de anticuerpos maternales contra el virus de la peste porcina clásica en lechones nacidos de marranas en granjas con diferentes estrategias de vacunación, Katherine J. Portilla, Albert Manchego S., Hermelinda G. Rivera, Mariluz Araínga, and Marcy Ramierz V.

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Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells., Changhai Tian, L. Charles Murrin, and Jialin C. Zheng

Submissions from 2008

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El virus de la diarrea viral en bovinos criollos de la Provincia de Melgar, Puno, Q. Richard Quispe, Ccama Albert S., Hermelinda G. Rivera, and Mariluz Araínga

Submissions from 2007

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Diarrea viral bovina y animales portadores del virus en hatos productores de leche de la irrigación de Majes, Arequipa, John C. Huaman G., Hermelinda G. Rivera, Mariluz Araínga, Cesar Gavidia Ch., and Alberto Manchego S.

Submissions from 2006

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Evaluación de anticuerpos contra el virus de la diarrea viral bovina de un hato en proceso de erradicación de la enfermedad., Zuniga Alfonso H., Hermelinda G. Rivera, Mariluz Araínga, and Alberto Manchego S.

Submissions from 2005

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Dinámica de seroconversión en hembras bovinas post eliminación de animales portadores del virus de la diarrea viral bovina., Jayashi Cesar F., Gavidia Cesar C., Mariluz Araínga, Alberto Manchego, and Hermelinda G. Rivera

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Anticuerpos contra el virus de la estomatitis vesicularen sajinos (Tayassu tajacu) de zoocriaderos de Iquitos y Pucallpa, Aldo D. Wilson, Mariluz Araínga, Hugo Galvez C., Alberto Manchego S., and Hermelinda G. Rivera

Submissions from 2003

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Efecto de la GnRH en el proceso del reconocimiento maternal de la preñez sobre la supervivencia embrionaria en alpacas., Mariluz Araínga, Victor Leyva V., Wilber Garcia V., and Enrique Franco LI.

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Actinomyces pyogenes Causante de aborto en bovinos, Mariluz Araínga, Nieves Sandoval Ch., Erik R. Zacharias, and Hermelinda Rivera G.