MicroRNAs are emerging as a hot topic in research, and rightfully so. They show great promise as targets of treatment and as markers for common human diseases, such as cancer and metabolic diseases. In this review, we address some of the basic questions regarding micro- RNA function in human disease and the clinical significance of microRNAs. Specifically, micro- RNAs in epigenetics, cancer, and metabolic diseases are discussed, with examples taken from cholangiocarcinoma and nonalcoholic fatty liver disease.
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Natarajan, Sathish Kumar; Smith, Mary A.; Wehrkamp, Cody J.; Mohr, Ashley M.; and Mott, Justin L., "MicroRNA Function in Human Diseases" (2013). Journal Articles: Biochemistry & Molecular Biology. 25.