Document Type
Capstone Experience
Graduation Date
12-2024
Degree Name
Master of Public Health
Department
Epidemiology
First Committee Member
Dr. Brittney L. Dickey, PhD, MPH
Second Committee Member
Dr. Shinobu Watanabe-Galloway, PhD
Abstract
Objective: To evaluate the association between smoking and coronary heart disease (CHD) incidence while adjusting for potential confounding factors, including age, education level, systolic blood pressure, BMI, serum cholesterol, and diabetes, using data from the Framingham Heart Study.
Methods: A cohort of 4,434 participants aged 32–70 years, free of CHD at baseline, was analyzed. Smoking status (current vs. non-current smokers) was the primary exposure, and CHD incidence was the outcome. Adjustments were made for confounders using multivariable logistic regression models. Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.
Results: CHD was diagnosed in 27.96% of participants. After adjustment, smoking was significantly associated with 40% increased odds of CHD (aOR=1.40, 95% CI: 1.21 1.62, p
Conclusions: In conclusion, we observed a significant association between smoking and CHD, emphasizing the need for targeted public health interventions to reduce smoking and reduce CHD risk.
Recommended Citation
Periera, Mona Melvin, "Comparative Study of Coronary Heart Disease Incidence in Smokers vs. Non Smokers: A Longitudinal Cohort Analysis from the Framingham Heart Study" (2024). Capstone Experience. 364.
https://digitalcommons.unmc.edu/coph_slce/364