ORCID (Optional)
https://orcid.org/0000-0001-8771-197X - Milan Terzic
https://orcid.org/0009-0002-9807-4819 - Yash Patel
Document Type
Case Report
Disciplines
Cardiology | Cardiovascular Diseases | Higher Education | Medicine and Health Sciences
Abstract
A 46-year-old bodybuilder presenting with new onset dyspnea found to have a new onset non-ischemic cardiomyopathy (CM) attributed to exogenous trenbolone and testosterone use. Steroid cessation and guideline-directed heart failure therapy led to notable recovery in left ventricular function supported by global longitudinal strain, ejection fraction and symptomatology.
Anabolic steroid-induced CM involves multiple mechanisms including lipid disturbances, hypertrophy, reduced receptor sensitivity, and cell damage. This case emphasizes the importance of recognizing anabolic steroid misuse as a potential cause of non-ischemic cardiomyopathy in middle aged men. With prompt discontinuation of steroids, remained abstinence and early initiation of guideline-directed medical therapy, myocardial recovery can occur.
DOI
https://doi.org/10.32873/unmc.dc.gmerj.6.2.003
Keywords
Trenbolone, Cardiomyopathy, Anabolic steroids, Testosterone, Heart Failure
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Recommended Citation
Terzic, M., , Patel, Y. B. Pumping Iron, Straining Hearts: Androgen Building Cardiomyopathy In a Middle Aged Bodybuilding Enthusiast. Graduate Medical Education Research Journal. 2024 Oct 31; 6(2).
https://digitalcommons.unmc.edu/gmerj/vol6/iss2/3
Table showing Timeline of Events
Figure 1.png (4469 kB)
Admission X ray showing cardiomegaly, pulmonary edema, and pleural effusions
Figure 2.png (5539 kB)
Prior X ray showing mild cardiomegaly
Figure 3.png (88 kB)
Initial Global Longitudinal Strain of -7%
Figure 4.jpeg (37 kB)
Global Longitudinal Strain of -10.6% with a non-specific pattern
Roids Cardio Case Report Consent.pdf (2391 kB)
Patient Consent
Cover letter Roids iCardio.docx (12 kB)
Cover Letter
Clean Copy of the Revised Version.docx (30 kB)
Clean Copy of the Revised Version
Marked Copy of the Revised Version.docx (41 kB)
Marked Copy of the Revised Version
Response to the Reviewers Comments.docx (12 kB)
Response to Reviewer