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ORCID (Optional)

https://orcid.org/0000-0001-8771-197X - Milan Terzic

https://orcid.org/0009-0002-9807-4819 - Yash Patel

Document Type

Case Report

Disciplines

Cardiology | Cardiovascular Diseases | Higher Education | Medicine and Health Sciences

Abstract

A 46-year-old bodybuilder presenting with new onset dyspnea found to have a new onset non-ischemic cardiomyopathy (CM) attributed to exogenous trenbolone and testosterone use. Steroid cessation and guideline-directed heart failure therapy led to notable recovery in left ventricular function supported by global longitudinal strain, ejection fraction and symptomatology.

Anabolic steroid-induced CM involves multiple mechanisms including lipid disturbances, hypertrophy, reduced receptor sensitivity, and cell damage. This case emphasizes the importance of recognizing anabolic steroid misuse as a potential cause of non-ischemic cardiomyopathy in middle aged men. With prompt discontinuation of steroids, remained abstinence and early initiation of guideline-directed medical therapy, myocardial recovery can occur.

DOI

https://doi.org/10.32873/unmc.dc.gmerj.6.2.003

Keywords

Trenbolone, Cardiomyopathy, Anabolic steroids, Testosterone, Heart Failure

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Table 1.docx (12 kB)
Table showing Timeline of Events

Figure 1.png (4469 kB)
Admission X ray showing cardiomegaly, pulmonary edema, and pleural effusions

Figure 2.png (5539 kB)
Prior X ray showing mild cardiomegaly

Figure 3.png (88 kB)
Initial Global Longitudinal Strain of -7%

Figure 4.jpeg (37 kB)
Global Longitudinal Strain of -10.6% with a non-specific pattern

Roids Cardio Case Report Consent.pdf (2391 kB)
Patient Consent

Cover letter Roids iCardio.docx (12 kB)
Cover Letter

Clean Copy of the Revised Version.docx (30 kB)
Clean Copy of the Revised Version

Marked Copy of the Revised Version.docx (41 kB)
Marked Copy of the Revised Version

Response to the Reviewers Comments.docx (12 kB)
Response to Reviewer

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