Title
A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues.
Document Type
Article
Journal Title
J Biomed Res
Publication Date
12-25-2020
Volume
35
Abstract
Since genetic engineering of pigs can benefit both biomedicine and agriculture, selecting a suitable gene promoter is critically important. The cytomegalovirus (CMV) promoter, which can robustly drive ubiquitous transgene expression, is commonly used at present, yet recent reports suggest tissue-specific activity in the pig. The objective of this study was to quantify ZsGreen1 protein (in lieu of CMV promoter activity) in tissues from pigs harboring a CMV-ZsGreen1 transgene with a single integration site. Tissue samples (
DOI Link
ISSN
1674-8301
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Recommended Citation
Desaulniers, Amy T; Cederberg, Rebecca A; Carreiro, Elizabeth P; Gurumurthy, Channabasavaiah B; and White, Brett R, "A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues." (2020). Journal Articles: Pharmacology & Experimental Neuroscience. 59.
https://digitalcommons.unmc.edu/com_pen_articles/59