Retinal optical coherence tomography manifestations of intraocular lymphoma.

Tin Yan Alvin Liu, Columbia University
Mohamed Ibrahim, Johns Hopkins University
Millena Bittencourt, Johns Hopkins University
Yasir J. Sepah, University of Nebraska Medical Center
Diana V. Do, University of Nebraska Medical Center
Quan Dong Nguyen, University of Nebraska Medical Center


PURPOSE: Primary central nervous system lymphoma (PCNSL) is a rare disease. The index report describes a patient with intraocular lymphoma secondary to recurrent PCNSL and corresponding retinal findings on spectral domain optical coherence tomography (SD-OCT).

METHODS: Case report.

RESULTS: OCT changes were documented and correlated with the clinical course of intraocular lymphoma progression in the index patient. The OCT changes, manifested as hyperreflective material accumulation in the intraretinal and subretinal pigment epithelial spaces, were caused by lymphomatous infiltration.

CONCLUSION: SD-OCT can be useful in diagnosing and monitoring the progression or regression of intraocular lymphoma with retinal involvement.