Document Type
Article
Journal Title
Tropical Diseases, Travel Medicine and Vaccines
Publication Date
2017
Volume
3
Abstract
Human immunodeficiency virus (HIV) sets several challenges for the development of a preventative HIV vaccine. Predictable, protective natural immunity against HIV does not occur and so unlike most other diseases for which vaccines exist, there are few guideposts from natural infection. Nonetheless, six vaccine efficacy trials have occurred. One in particular, the Thai trial called RV144, showed partial protective efficacy and potential ways ahead to a better vaccine approach. This coupled with other lessons from studies of acute infections as well as an increasingly complex knowledge of HIV-related vaccine immunology bring hope that a vaccine solution might be reached for this pervasive and deadly pandemic.
DOI Link
ISSN
2055-0936
Creative Commons License
This work is licensed under a
Creative Commons Public Domain Dedication 1.0 License.
Rights
U.S. Government Work
Recommended Citation
Brett-Major, David; Crowell, T. A.; and Michael, N. L., "Prospecting for an HIV Vaccine" (2017). Journal Articles: Epidemiology. 36.
https://digitalcommons.unmc.edu/coph_epidem_articles/36