Follow

Theses/Dissertations from 2024

PDF

Targeting LIFR/c-Myc/DDX21 Axis to Overcome Docetaxel Resistance in Prostate Cancer, Sushanta Halder

PDF

Homeobox A10: Regulator of Pancreatic Cancer Progression and Survival, Sophia G. Kisling

PDF

Asporin/Crabp2 Axis Drives "Cell-State" Transition to Enable Neuroendocrine-Like Phenotype In Prostate Cancer, Shobhit P. Lall

PDF

Role of PYCR2 in Colorectal Cancer, Raju Lama Tamang

PDF

Mucins: Drivers of Cancer Cell and Microenvironment Crosstalk in Pancreatic Cancer, Xiaoqi Li

PDF

Unraveling the role of GJB3 in lung adenocarcinoma, Swathi M. Priyanka

PDF

Determining if Cx45 Acts as an Arrythmogenic Substrate in the Diseased Myocardium, Stephen R. Sobota

Theses/Dissertations from 2023

PDF

Gap Junctional Intercellular Communication: Role of Cx43 Phosphorylation by Tyrosine Kinases, Ishika Basu

PDF

Exploiting Vulnerabilities in the Ras-Rac Signaling Pathway for the Selective Targeting of Pancreatic Cancer Cells, Neha Chaudhary

PDF

Examining CAF Heterogeneity in Pancreatic Cancer, Nidhi V. Dwivedi

PDF

MnTnBuOE-2-PyP Sensitizes Castrate Resistant Prostate Cancer to Androgen Deprivation Therapies, Ariel Moats

Theses/Dissertations from 2022

PDF

Metoprolol Disrupts Sterol Biosynthesis through Inhibition of 7-Dehydrocholesterol Reductase (DHCR7), Luke B. Allen

PDF

Mechanisms of Sorting and Fission at the Endosomes, Kanika Dhawan

PDF

Characterizing a MUC4-Based Nanovaccine and Enhancing its Efficacy by Targeting the Endothelin Axis, Mansi Gulati

PDF

Neuropilin-2 in Advanced Prostate Cancer and its Targeting with Novel Small Molecule Inhibitors, Ridwan Islam

PDF

Novel Molecular Mechanisms of C-Terminal Eps15 Homology Domain (EHD) Proteins in Endocytic Trafficking and Primary Ciliogenesis, Tyler M. Jones

PDF

The Role of Parkin in Mitochondrial DNA, Eliezer Lichter

PDF

Underlying Mechanism of Ovarian Reserve Preservation from Gonadotoxicity, Yi Luan

PDF

The Relationship between p66Shc Expression and Proliferation of Human Prostate Cancer Cells with MnTnBuOE-2-PyP Treatment, Thao Nhi Radik

PDF

PAF1/PD2 Augments Pancreatic Cancer Progression and Mediates Radiation and Chemoresistance, Sanchita Rauth

PDF

Dysregulation of miR-10a Promotes Cancer Features in Cholangiocarcinoma, Matthieu Spriet

Theses/Dissertations from 2021

PDF

Development of In-silico Pipelines for Identification and Characterization of Biomarker Panels and Therapeutic Interventions in Gastro-Intestinal (GI) Cancers, Pranita Atri

PDF

Secreted Mucin 5AC-Mediated Epithelial and Stromal Modulations Augment Pancreatic Cancer Aggressiveness, Koelina Ganguly

PDF

Fibroblast Growth Factor Receptor 4 and R4-ICD Increased Proliferation, Cell Survival and Metastasis in Cholangiocarcinoma, Yamnah Hafeji

PDF

A PKCα-Mediated Growth Suppressive MEK-ERK Signaling Axis in Intestinal Epithelial Cells, Navneet Kaur

PDF

Nuclear Receptor Coactivator 3 in Endoplasmic Reticulum Stress and Stress Granule Dynamics in Pancreatic Cancer, Andrew Kisling

PDF

Molecular Mechanisms of Aberrant Protein Glycosylation in Pancreatic Cancer Stemness and Metastasis, Frank Leon

PDF

Mucin and Splice Variant Profiles of Pancreatic Adenocarcinoma Predict Patient Survival and Subtyping, Christopher M. Thompson

Theses/Dissertations from 2020

PDF

Deciphering the Catalytic Mechanism of Human Manganese Superoxide Dismutase, Jahaun Azadmanesh

PDF

The Role of the CXCR3 Signaling Axes in Pancreatic Ductal Adenocarcinoma, Andrew C. Cannon

PDF

Novel Detection and Treatment Strategies for Pancreatic Ductal Adenocarcinoma, Joseph Carmicheal

PDF

Novel regulatory roles of endocytic membrane trafficking proteins in mitochondrial homeostasis, Trey Farmer

PDF

Molecular Insights Into PAF-1 Mediated Pancreatic Homeostasis, Stemness, and Cancer Progression, Saswati Karmakar

PDF

Targeted Therapies in Select Gastrointestinal Cancers and Cancer Cachexia, Scott Mulder

PDF

Elucidating the role of Ecdysoneless in mRNA processing, Irfana Saleem

PDF

Molecular Mechanisms of Manganese Porphyrin Compounds in the Prevention of Radiation-Induced Fibrosis, Shashank Shrishrimal

PDF

Mechanisms by Which MnTE-2-PyP Suppresses Prostate Cancer Cell Growth, Yuxiang Zhu

Theses/Dissertations from 2019

PDF

Cholesterol Biosynthesis in the Nervous System with an Emphasis on Desmosterolosis, Luke Allen

PDF

Molecular Mechanisms Governing Muscle Wasting in Cancer, Aneesha Dasgupta

PDF

The Role of Reactive Oxygen Species in Regulating Macrophage and Fibroblast Activation Within the Breast Cancer Tumor Microenvironment, Brandon J. Griess

PDF

Developing Targeted Therapy against Pancreatic Cancer, Garima Kaushik

PDF

The Role of ROS in the Progression and Treatment of Castration-Resistant Prostate Cancer, Dannah R. Miller

PDF

Induction and metastasis of cancer stem cells in pancreatic cancer, Rama Krishna Nimmakayala

PDF

HDAC1 is a Required Cofactor of CBFβ-SMMHC and a Therapeutic Target in Inversion 16 Acute Myeloid Leukemia, Lisa E. Richter

PDF

Identification of Pathways Required for the Survival of Inversion(16) Acute Myeloid Leukemia, Yiqian Wang

PDF

Defining the Role of Tyrosine Phosphorylation in the Regulation of Connexin43 in Cardiac Diseases, Li Zheng

Theses/Dissertations from 2018

PDF

Inhibition of RAD52-based DNA repair for cancer therapy, Mona Al-Mugotir

PDF

MUC4 Based Immunotherapy for Pancreatic Cancer, Kasturi Banerjee

PDF

Functional and Mechanical Role of Splice Variant of Mucin4 (MUC4/X) and Trefoil Factors in Pancreatic Cancer Pathogenesis, Rahat Jahan

PDF

Connexin32: Sorting, Endocytosis and Assembly, Anuttoma Ray

PDF

Towards the Identification of the Molecular Mechanism Responsible for RPA:RAD52 Complex Formation, Lucas Struble

PDF

Intra- and Inter-Molecular Signaling in a Cardiac Connexin: Role of Cytoplasmic Domain Dimerization and Phosphorylation, Andrew J. Trease

PDF

Modulating Hallmarks of Cholangiocarcinoma, Cody Wehrkamp

PDF

The Beta-Catenin/MUC1.CT Interaction in Pancreatic Cancer, Edwin Wiest

Theses/Dissertations from 2017

PDF

Molecular mechanisms of C-terminal Eps15 Homology Domain containing (EHD) protein function, Kriti Bahl

PDF

Aberrant Glycosylation In Pancreatic Cancer Progression, Seema Chugh

PDF

Role of Endothelin Axis in Pancreatic Tumor Microenvironment, Suprit Gupta

PDF

Novel Therapeutic Strategies for Treatment of Castration-Resistant Prostate Cancer, Matthew A. Ingersoll

PDF

Defining the Role of Neuropilin-2 in Macrophages: Implications in Tumor Associated Macrophages in Pancreatic Cancer, Sohini Roy

PDF

The Role of Semaphorin 5A in Pancreatic Cancer Progression and Metastasis, Sugandha Saxena Dr.

PDF

Basal and Experience Dependent Ampar and Synapse Dynamics: Alterations in a Mouse Model of Fragile X Syndrome, Anand Suresh

PDF

The Rise and Fall of the Bovine Corpus Luteum, Heather Talbott

Theses/Dissertations from 2016

PDF

Role of AKT2 in Cell Survival, Establishment and/or Maintenance of Colorectal Cancer Metastasis, Ekta Agarwal

PDF

Mitogen and Morphogen Signaling Dysregulation: Pathophysiological Influence in Pancreatic Cancer and Alzheimer’s Disease, Eric Cruz

PDF

Role of DDR1 in Pancreatic Cancer, Huocong Huang

PDF

Novel Regulatory Mechanisms and Functions of MUC4 in Pancreatic Cancer, Suhasini Joshi

PDF

Secretory Mucin MUC5AC in Gastrointestinal Malignancies, Shiv Ram Krishn

PDF

The role of oncogenic KRAS in initiation, progression and maintenance of pancreatic cancer, Nirakar Rajbhandari

PDF

The Mechanism of Tubular Recycling Endosome Biogenesis, Shuwei Xie

PDF

Exploitation of the Ligand-Binding Properties of the Mannose 6-Phosphate/Insulin-Like Growth Factor II (IGF-II) Receptor to Inhibit IGF-II-Dependent Growth of Cancer Cells, Megan Zavorka Thomas

PDF

Study of the Structure-Related Functions of Eukaryotic Primase-POL ALPHA Complex During Replication, Yinbo Zhang

Theses/Dissertations from 2015

PDF

Transcriptional and Post-transcriptional Regulation of Hepcidin and Iron Metabolism by Lipid Signaling in the Liver, Sizhao Lu

PDF

Regulation of the transmembrane mucin MUC4 by Wnt/β-catenin in gastrointestinal cancers, Priya Pai

PDF

Regulatory roles of MICAL-L1 and EHD1 in cell signaling and mitosis, James B. Reinecke

PDF

Investigation of behavioral and cellular changes in the Maternal Immune Activation model of autism spectrum disorders, Shreya Roy

PDF

Control of the Basal Recycling and Surface Expression of Epidermal Growth Factor Receptor by the Endocytic Recycling Regulator EHD1 Utilizing a Pathway Shared by RUSC2, Eric Tom

PDF

Multifunctional role of pancreatic differentiation 2 (PD2) in pancreatic cancer, Arokia Priyanka Vaz

Theses/Dissertations from 2014

PDF

Mucin 16 (MUC16) in pancreatic cancer: expression and functional studies, Dhanya Haridas

PDF

Identification and developmental expression of RanGAP1 in mouse lenses and analysis of its functions in mitosis of lens epithelial and Hela cells, Weike Ji

PDF

The cytoplasmic tail of connexin232 in gap junction assembly, Parul Katoch

PDF

The role of Cbl and Cbl-b ubiquitin ligases in mammary gland development and mammary stem cell homeostasis, Bhopal Mohapatra

PDF

Role of Membrane Bund Mucins (MUC4, MUC16 and MUC17) in Gastro Intestinal (GI) Cancer, Das Srustidhar

Theses/Dissertations from 2013

PDF

C-terminal EPS 15 homology domain (EHD) protein-mediated membrane vesiculation and control of glycosylphosphatidylinositol (GPI)-anchored protein trafficking, Bishuang Cai

PDF

The biophysical characterization and effects of pH and phosphorylation on the secondary structure of the intrinsically disordered connexin43 carboxyl terminus attached to the 4th transmembrane domain, Rosslyn Grosely

PDF

Structural characterization of the connexin45 carboxyl-terminal domain and its interactions with molecular partners, Jennifer Lynn Kopanic

PDF

Functions of MICAL-family proteins in tubular recycling endosome biogenesis and cytoskeletal regulation, Sai Srinivas Panapakkam Giridharan

PDF

The role of mucins in the pathophysiology of pancreatic cancer with a focus on MUC7, Neeley Remmers

Theses/Dissertations from 2012

PDF

Roles of paired box 6 and its downstream genes in human pancreatic cancer, Mi Deng

PDF

Role of novel cell cycle regulator(s) in pancreatic cancer, Parama Dey

PDF

Regulation of ocular lens differentiation by protein sumoylation, Lili Gong

PDF

The role of DNA methyltransferases in cancer, Trevor D. Hedman

PDF

Endocytosis of connexin43 and gap junction assembly, Kristen E. Johnson

PDF

Smoking and pancreatic cancer, Navneet Momi

PDF

The structural insights to the mechanisms of EHD3 EH-domain binding with NPF-containing proteins, Calliste Reiling

PDF

Structural characterization of the connexin32 carboxyl-terminal domain and mutants that cause charcot-marie-tooth disease: effects on protein partner interactions, Kelly L. Stauch

Theses/Dissertations from 2011

PDF

Novel insights into the molecular diagnosis and therapy of pancreatic cancer, Subhankar Chakraborty

PDF

Role of transforming growth factor beta 1 in the regression of the corpus luteum, Dulce Maroni

PDF

Modulated crystals of profilin:actin, Jason Porta

PDF

Macromolecular therapy for improved treatment of rheumatoid arthritis, Lingdong Quan

PDF

The roles of Rab effectors and their interaction partners in endocytic trafficking, Juliati Rahajeng