Document Type
Article
Journal Title
Journal of the International Association of Providers of AIDS Care
Publication Date
2021
Volume
20
Abstract
As with other chronic conditions, adherence to daily medications remains a challenge for many individuals living with HIV due to structural, behavioral, and social barriers. Unfortunately, high levels of adherence to antiretroviral therapy are required to maintain virologic suppression. Alternative approaches are being explored to decrease the burden of daily pill administration, including long-acting injectable, oral, and implantable products. Phase 3 data support the efficacy of nanoformulated injectable cabotegravir and rilpivirine for HIV treatment in patients with undetectable viremia, but we have yet to learn how this strategy may benefit those with medication adherence challenges. Despite this, the affected community and HIV providers are very interested in exploring the role of long-acting therapies to address some types of barriers to medication adherence. This review summarizes available information about the potential for long-acting therapy to improve adherence for some patients and outlines associated opportunities and challenges with the implementation of long-acting therapy for the treatment and prevention of HIV.
DOI Link
ISSN
2325-9582
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Recommended Citation
Scarsi, Kimberly and Swindells, Susan, "The Promise of Improved Adherence With Long-Acting Antiretroviral Therapy: What Are the Data?" (2021). Journal Articles: Infectious Diseases. 10.
https://digitalcommons.unmc.edu/com_infect_articles/10