Something Smells Fishy: How Lipid Mediators Impact the Maternal-Fetal Interface and Neonatal Development

Authors

Maranda Thompson, University of Nebraska Medical CenterFollow
Arzu Ulu, University of California Riverside
Maheswari Mukherjee, University of Nebraska Medical CenterFollow
Ana G. Yuil-Valdes, University of Nebraska Medical CenterFollow
Melissa K. Thoene, University of Nebraska Medical CenterFollow
Matthew Van Ormer, University of Nebraska Medical CenterFollow
Rebecca Slotkowski, University of Nebraska Medical CenterFollow
Teri Mauch, University of Nebraska Medical CenterFollow
Ann Anderson-Berry, University of Nebraska Medical CenterFollow
Corrine K. Hanson, University of Nebraska Medical CenterFollow
Tara M. Nordgren, University of California Riverside
Sathish Kumar Natarajan, University of Nebraska - Lincoln

Document Type

Article

Journal Title

Biomedicines

Publication Date

2023

Volume

11

Abstract

Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is one modifiable factor that can impact inflammation. Omega-3 and -6 fatty acids obtained through the diet are metabolized into bioactive compounds that effect inflammation. Recent evidence has shown that the downstream products of omega-3 and -6 fatty acids may influence physiology during pregnancy. In this review, the current knowledge relating to omega-3 and omega-6 metabolites during pregnancy will be summarized.

DOI Link

10.3390/biomedicines11010171

ISSN

2227-9059

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Thompson, Maranda; Ulu, Arzu; Mukherjee, Maheswari; Yuil-Valdes, Ana G.; Thoene, Melissa K.; Van Ormer, Matthew; Slotkowski, Rebecca; Mauch, Teri; Anderson-Berry, Ann; Hanson, Corrine K.; Nordgren, Tara M.; and Natarajan, Sathish Kumar, "Something Smells Fishy: How Lipid Mediators Impact the Maternal-Fetal Interface and Neonatal Development" (2023). Journal Articles: Pediatrics. 30.
https://digitalcommons.unmc.edu/com_peds_articles/30