Document Type

Article

Journal Title

Journal of clinical child and adolescent psychology

Publication Date

11-2009

Volume

38

Abstract

This article explores aspects of family environment and parent-child conflict that may predict or moderate response to acute treatments among depressed adolescents (N = 439) randomly assigned to fluoxetine, cognitive behavioral therapy, their combination, or placebo. Outcomes were Week 12 scores on measures of depression and global impairment. Of 20 candidate variables, one predictor emerged: Across treatments, adolescents with mothers who reported less parent-child conflict were more likely to benefit than their counterparts. When family functioning moderated outcome, adolescents who endorsed more negative environments were more likely to benefit from fluoxetine. Similarly, when moderating effects were seen on cognitive behavioral therapy conditions, they were in the direction of being less effective among teens reporting poorer family environments.

MeSH Headings

Adolescent, Child, Cognitive Therapy, Depressive Disorder, Major, Double-Blind Method, Family, Female, Fluoxetine, Humans, Male, Research Design, Serotonin Uptake Inhibitors, Single-Blind Method, Social Environment, Treatment Outcome

ISSN

1537-4424

Comments

This is an Accepted Manuscript of an article published by Taylor & Francis Group in Journal of clinical child and adolescent psychology on 11/2009, available online at: http://www.tandfonline.com/10.1080/15374410903297148.

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Psychiatry Commons

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