Document Type
Article
Journal Title
BMC Cancer
Publication Date
2022
Volume
22
Abstract
BACKGROUND: Cancer clinical trials (CCTs) are essential for cancer care, yet the evidence is scarce when it comes to racial disparities in CCT participation among cancer survivors in the Midwest. This study aimed to 1) assess disparities in the awareness of and willingness to participate in CCTs between African American and White cancer survivors; and 2) compare perceptions about CCTs between the two racial groups.
METHODS: The study was based on cross-sectional data from the survey "Minority Patient Participation in Cancer Clinical Trials" that collected information from 147 Black and White cancer survivors from Nebraska between 2015 and 2016. Chi-square tests and logistic regressions were used to assess differences between Black and White cancer survivors regarding their awareness, willingness, and perceptions associated with CCT participation.
RESULTS: After adjusting for the effects of socio-demographic, health status, and psychosocial variables, Black cancer survivors were much less likely than White cancer survivors to be aware of CCTs (AOR 0.26; CI 0.08-0.81), to express willingness to participate in CCTs (AOR 0.03; CI 0.01, 0.32) and to actually participate in CCTs (AOR 0.13; CI 0.04-0.38). Black cancer survivors reported a lower level of trust in physicians and were less likely than White cancer survivors to believe that CCTs make a significant contribution to science.
CONCLUSIONS: Relative to White cancer survivors, Black cancer survivors had much lower awareness of and willingness to participate in CCTs. Part of these differences might be related to the differential perception of CCTs, psychosocial factors, and trust in physicians between the two groups.
MeSH Headings
African Americans, Cancer Survivors, Clinical Trials as Topic, Cross-Sectional Studies, Humans, Neoplasms, Patient Participation
DOI Link
ISSN
1471-2407
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Kumar, Gaurav; Kim, Jungyoon; Farazi, Paraskevi A.; Wang, Hongmei; and Su, Dejun, "Disparities in Awareness of and Willingness to Participate in Cancer Clinical Trials Between African American and White Cancer Survivors" (2022). Journal Articles: Epidemiology. 169.
https://digitalcommons.unmc.edu/coph_epidem_articles/169