Thirty-Day Unplanned Readmission and Its Effect on 90-Day Mortality in Hepatocellular Carcinoma Patients Undergoing Partial Hepatectomy

Authors

Yongyue Qi, Creighton University
Tricia LeVan, University of Nebraska Medical CenterFollow
Gleb Haynatzki, University of Nebraska Medical CenterFollow
Chandrakanth Are, University of Nebraska Medical CenterFollow
Evi A. Farazi, University of Nebraska Medical CenterFollow

Document Type

Article

Journal Title

Journal of Gastroenterology and Hepatology Research

Publication Date

2020

Volume

9

Abstract

Background: Despite advances of surgical techniques, hepatectomy continues to be potentially dangerous and is associated with postoperative mortality, morbidity and readmission. The objective of this study was to determine the effect of 30-day unplanned readmission on ‘conditional’ 90-day mortality among hepatocellular carcinoma (HCC) patients who underwent partial hepatectomy.

Methods: National Cancer Database (NCDB) was queried from 2004 to 2012 for patients with hepatocellular carcinoma (HCC) who underwent partial hepatectomy. Thirty-day unplanned readmission rate, and associated risk factors, was determined for 7,696 patients. The association between 30-day unplanned readmission and conditional 90-day mortality was further addressed.

Results: The 30-day unplanned readmission rate for patients with HCC who underwent partial hepatectomy was 5.2%. Risk factors associated with 30-day unplanned readmission were sex, race/ethnicity, Charlson-Deyo score, and annual hospital hepatectomy volume. An overall adjusted odds of having conditional 90-day mortality was 2.325 times higher (95% CI 1.643 - 3.219) among patients with a history of 30-day unplanned readmission than those without. This association was dependent on age, sex, race/ethnicity, insurance status, alpha-fetoprotein (AFP), liver fibrosis, Charlson-Deyo comorbidity score and annual hospital hepatectomy volume.

Conclusion: Efforts in patient care should be taken to reduce 30-day unplanned readmission after partial hepatectomy for patients with HCC to reduce conditional 90-day mortality.

DOI Link

10.17554/j.issn.2224-3992.2020.09.973

ISSN

2224-6509

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Recommended Citation

Qi, Yongyue; LeVan, Tricia; Haynatzki, Gleb; Are, Chandrakanth; and Farazi, Evi A., "Thirty-Day Unplanned Readmission and Its Effect on 90-Day Mortality in Hepatocellular Carcinoma Patients Undergoing Partial Hepatectomy" (2020). Journal Articles: Epidemiology. 67.
https://digitalcommons.unmc.edu/coph_epidem_articles/67