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Theses/Dissertations from 2022

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ERα as a Modulator of the Sle1b Lupus Susceptibility Locus and B Cell Receptor Signaling, Jared H. Graham

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Extracellular Mechanotransduction in Marfan Syndrome: An Equivalence Principle, Stephen Haller

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Determining the Role of miR-133a in the Diabetic Heart, Tyler Kambis

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Modulating Cellular Senescence to Improve Age-Associated Wound Healing Impairment, Upasana Niyogi

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Genome-Wide Distribution of Acape1 and Its Implications in DNA Repair and Transcription, Mason Tarpley

Theses/Dissertations from 2021

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The Rotator Cuff Tendon-to-Bone Interface: Maturation, Aging, and 3D Bioprinting for Regeneration, Xiping Jiang

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USP11 and USP7 Deubiquitinases Regulate SPRTN Auto-proteolysis and SPRTN-mediated DNA-protein Crosslink Repair, Megan C. Perry

Theses/Dissertations from 2020

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DNA Polymerase ε: Replication Error Prevention and Consequences of a Cancer-Associated Mutation, Chelsea R. Bulock

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Exosomes Secreted under Hypoxia Enhance Stemness in Ewing’s Sarcoma and Transform Microenvironment Cells, Matthew J. Kling

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Molecular and Behavioral Studies in CDKL5 Deficiency Disorder, Ethan Schroeder

Theses/Dissertations from 2019

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The Role of Neutrophils in Pancreatic Cancer, Edson DeOliveira

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Characterization of the Role of Acetylated APE1 in DNA Damage Repair and Transcriptional Regulation, Shrabasti Roychoudhury

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Ecdysoneless, a novel regulator of Ca2+ homeostasis and metabolism, Aniruddha Sarkar

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Prostaglandins and Kidney Function: A Comparison Between the Cortical and Inner Medullary Collecting Duct on Prostaglandin Production, Dane N. Wilson

Theses/Dissertations from 2018

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Red Panda: A Novel Method for Detecting Variation in Single-Cell RNA Sequencing, Adam Cornish

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Determinants of multi-scale patterning in growth plate cartilage, Alek Erickson

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The Effect of Dust Mite extract on Esophageal Tight Junctions in Eosinophilic Esophagitis, Kyle Hinz

Theses/Dissertations from 2017

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Analysis of Graded Gross Anatomy Dissections and Demonstrations as a Supplemental Educational Tool, Stephanie Leanne Cummings

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Requirement of EHD Family of Endocytic Recycling Regulators for T-Cell Functions, Fany M. Iseka

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A Cadaveric Study of Coronary Artery Variations, Mitchell Lee Milanuk

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The Roles of Ecdysoneless in Endoplasmic Reticulum Stress and Oncogenesis, Appolinaire A. Olou

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Understanding the Chondrogenic Potential of Articular Chondrocytes, Krishna Sarma

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Anatomical Variations of the Sciatic Nerve Divisions in Relation to the Piriformis Muscle and Clinical Implications, Jonathan I. Van Erdewyk

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Comparative Molecular Characterization of Typical and Exceptional Responders in Glioblastoma, Kristin Wipfler

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Identification of Important Regulators of Colon Cancer Tumorigenesis By Functional Screening, Haowei Yi

Theses/Dissertations from 2016

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Role of ECDYSONELESS in ERBB2/HER2 Mediated Breast Oncogenesis, Shalis A. Ammons

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Role of Cell Type and Genetic Alterations in Driving Breast Cancer Pathogenesis, Divya Bhagirath

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Restriction Enzyme Generated Next-Generation Sequencing Libraries and Genetic Risk Modifiers of BRCA1 Mutation Carriers, Bradley Downs

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Utilization of Dissection Videos in Graduate-Level Gross Anatomy Education: An Analysis of Student Confidence, Utilization, and Scoring Outcomes, Jessica Gamerl

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The Role of ADA3 Overexpression in Proliferation Through Enhancing MYC Expression, Nicolas I. Griffin

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The Role of DNA Methyltransferases in Normal and Malignant Hematopoiesis, Staci Haney

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ChimeRScope: a novel alignment-free algorithm for fusion gene prediction using paired-end short reads, You Li

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Gross Anatomy Dissection Videos: Effect on Student Dissection Confidence and Laboratory Examination Scores, Kevin J. Selting

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SPROUTY 2: A Novel Attenuator of B Cell Receptor and MAPK Signaling in Chronic Lymphocytic Leukemia, Ashima Shukla

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Defining the role of Interferon Regulatory Factor 4 in Chronic Lymphocytic Leukemia., Vipul Shukla

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Regulation of Alteration/Deficiency in Activation 3 (ADA3) by Acetylation and its Role in Cell Cycle Regulation and Oncogenesis, Shashank Srivastava

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Role of B cell and hematopoietic cell intrinsic actions of ERα in lupus pathogenesis, Dana E. Tabor

Theses/Dissertations from 2015

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Role of Cbl and Cbl-b ubiquitin ligases in the regulation of hematopoiesis, Wei An

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Functional characterization of the roles of endocytic recycling regulator EHD1 using in vivo and in vitro analyses, Priyanka Arya

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Role of ecdysoneless protein in the regulation of cell cycle progression and breast oncogenesis, Aditya R. Bele

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The Role of Tumor Suppressor Co-Chaperone CHIP/STUB1 in ERBB2-Mediated Oncogenesis, Haitao Luan

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Biochemical characterization of alternation deficiency in activation 3 (ADA3) and its role in cell cycle regulation and mammary gland development, Shakur Mohibi

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Role of C-terminal protein-protein interactions in mutant CBL-induced leukemogenesis, Scott Andrew Nadeau

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Impact of estrogen receptor alpha signaling and apoptosis in Tcells on the development of murine lupus, Richard Keith Nelson

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Fine structure mapping of the Mom5 genetic modifier of intestinal tumorigenesis and evaluation of Mom5 candidate, Karla Lynn Otterpohl

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Impact of Estrogen Receptor Alpha on SLE1-Induced Loss of Tolerance, Shayla D. Yoachim

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Identification of novel MiRNAs contributing to drug resistance in colorectal cancer, Yang Zhang

Theses/Dissertations from 2013

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A role for the endocytic recycling regulator EHD1 in macrophage fusion and proliferation, Oluwadamilola Adeyanju Adepegba

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SOX9 in mammary stem progenitor cells and breast cancer progenitor cells and breast cancer, Emily Elizabeth Edwards

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Direct conversion of astrocytes into telencephalic neural progenitor cell-like cells with defined transcriptional factors, Kangmu Ma

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The role of Sox9 in mammary gland development and stem progenitor cell maintenance, Gautam K. Malhotra

Theses/Dissertations from 2012

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Characterization and targeting of therapy-resistant mantle cell lymphoma, Adam Kyle Ahrens

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Molecular and cellular determinants of lymph node microenvironment-induced immunosuppression in chronic lymphocytic leukemia, Christine E. Gilling-Cutucache

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Understanding the physiological roles of tyrosine kinase regulation by CLB-C using compound knockouts of CBL-Family, Sarah Marie Scheffe-Driskell

Theses/Dissertations from 2011

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Identification of gene networks and regulatory mechanisms in the murine retina, Austin Jelcick

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The development, characterization and targeting of therapy-resistant mantle cell lymphoma, Tara Marie Nordgren

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Characterization and mapping of a novel mouse model for retinal vasculature defects, Andy W. Yang

Theses/Dissertations from 2010

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Gene expression profiling of CLL cells from different tissue sites : identification of genes involved in survival, proliferation, and progression, Amit K. Mittal

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The role of nuclear receptor genes in retinal development and diseases, Nissa J. Mollema

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A role for interferon regulatory factor-4 (IRF-4) in B cell receptor editing and B cell tumorigenesis, Simanta Pathak

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Regulation of multipotential mesenchymal stomal cell differentiation, Sonal R. Tuljapurkar

Theses/Dissertations from 2009

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Modulation of intestinal tumorigenesis in Apcmin, Alicia G. Cleveland

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Characterization of Renag1 : a locus conferring unilateral renal agenesis and a white-spotting pattern in rattus norvegicus, Tessa W. Commers

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Influence of micro-environmental factors on the stem cell-like and tumorigenic properties of potential tumor-initiating cells in murine model of mantle cell lylmphoma, Abigail C. Hielscher

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The role of the n-methyl-d-aspartate receptor in heart development: a gene knockdown model using SiRNA, Octavian V. Lie

Theses/Dissertations from 2008

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Desmosome disassembly during TGF-ß induced epithelial to mesenchymal transition, Sarah A. Keim-Janssen

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Vaccine based immunotherapy for murine large B cell, lymphoma, Gayathri J. Kollessery

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The role of endoplasmic reticulum stress in ocular disease, Michael L. Mulhern

Theses/Dissertations from 2007

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Dendritic cell-based therapy for mantle cell lymphoma, Corey M. Munger

Theses/Dissertations from 2006

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Differential gene expression in B cell chronic lymphocytic leukemia patients with different clinical outcomes, Avadhut D. Joshi

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Antitumor effects of umbilical cord blood effector cells : a functional, ultrastructural, and phenotypic analysis, Erin M. Myers-Clark

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A comparative evaluation of teaching methods in an introduction neuroscience course for physical therapy students, Gilbert M. Willett

Theses/Dissertations from 2005

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Influence of somatic genomic aberrations on gene expression in human chronic lymphocytic leukemia, John D. Dickinson

Theses/Dissertations from 2002

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Hyperhomocysteinemia and impaired extra-embryonic vascular development : a mechanism involving nitric oxide synthesis, Kimberly Eastep Latacha

Theses/Dissertations from 2001

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Characterization of numb expression and function in the vertebrate retina, Constance M. Dooley

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Homocysteine inhibits retinoic acid signaling : a mechanism for homocysteine-induced congenital heart defects, Aimee L. Limpach

Theses/Dissertations from 2000

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Characterization of a T cell receptor [gamma] gene in the African clawed frog, Xenopus laevis, Melanie Kitzan

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Homocysteine signaling mechanisms in vascular smooth muscle cell proliferation, Rodney R. Miles

Theses/Dissertations from 1999

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LHRH neuronal migration and olfactory nerve axon pathfinding in the avian embryo, Chen Gao

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In Vitro analysis of factors influencing LHRH neuronal differentiation in the avian olfactory placode, Marian R L Maas

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Abdominal aortic aneurysms : signal transduction pathways involved in MT-1 MMP regulation and its role in MMP-2 activation, Alisa J. Nollendorfs

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Possible mechanisms of homocysteine teratogenicity in the chick embryo, Georgianna L. Witt

Theses/Dissertations from 1998

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Vascular smooth muscle heterogeneity as a function of ontogeny : myb and protein kinase C involvement in DNA synthesis, proliferation and collagen ╬▒1(I) expression, Michael L. Dalton

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Anatomical analysis of synaptic density in the arcuate nucleus of the adult and middle age female rat, Constance Theresa Moore

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The maintenance of lymphoma by the bone marrow microenvironment, Colin D. Weekes

Theses/Dissertations from 1997

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Transposition in the western mosquitofish, Gambusia affinis affinis (Baird and Girard, 1853) : studies on an ontogenetic mechanism that remodels the axial and appendicular morphology and behavior, Eduardo Rosa-Molinar

Theses/Dissertations from 1996

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Development and post-transplantation repopulation of lymphocytes in Peyer's Patches and small intestinal epithelium of mice, Amy L. Vetter

Theses/Dissertations from 1995

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An investigation of chronic and fulminant hepatic encephalopathy : studies utilizing a chronic human and fulminant animal model, Neil Scott Norton

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Functional and phenotypic analysis of GM-CSF mobilized human blood stem cells : comparison with other stem cell sources IN VITRO and therapeutic effects of stem cells and cytokines against residual lymphoma IN VIVO, David J. Verbik

Theses/Dissertations from 1994

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Characterization of lineage restricted forms of a xenopus CD45 homologue, Laura C. Barritt

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Patellofemoral disorders : is timing of vastus medialis obliquus and vastus lateralis muscle activation a factor?, Gilbert Michael Willett

Theses/Dissertations from 1993

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Development of hemopoietic cells in xenopus liver, Xiao-Dong Chen

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A comparison of trunk muscle activation patterns in infant kicking and stepping behaviors, Sandra Louise Jensen-Willett

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Variations in the kinematic, temporal-distance and electromyographic characteristics of children with cerebral palsy who exhibit genu recurvatum, Anne Marie Sojka

Theses/Dissertations from 1992

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Chronic cocaine cardiotoxicity in a chronically-instrumented conscious dog model, Keith Winston Lawson

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The role of bone marrow derived stromal populations in lymphohematopoietic differentiation, Xiaoying Qiao

Theses/Dissertations from 1991

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Biological and functional characterization of lymphoma- associated immunosuppressive molecules, Wei-min Hao

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Development and evaluation of a still cast video unit for teaching basic radiology, Roy W. Osborn

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The mechanism of the development of resistance to methemoglobinemia, Xin Wang

Theses/Dissertations from 1990

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The cardiovascular threshold responses to norepinephrine in dogs, Jason L. Bespalec