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Theses/Dissertations from 2024

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Development of Long-Acting Antiviral and Antimicrobial Prodrug Nanoformulations, Srijanee Das

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The Unfolding Saga: The Role of the ClpC Unfoldase in the Development and Differentiation of Chlamydia Trachomatis, Aaron Jensen

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Understanding the Role of Malondialdehyde-Acetaldehyde Adducts (MAA) in Inflammatory Bowel Disease, Megan L. Otte

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Adaptation Through Mutation: Arginine Auxotrophy in Staphylococcus aureus, Itidal Reslane

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Therapeutic Effects of Targeting the Heme Degradation Pathway in Prostate Cancer, Ramia J. Salloom

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A Tale of Two Proteins: An Investigation of Recruitment of Eukaryotic Proteins FLI1 And LRRF1 to the Chlamydial Inclusion Membrane, Natalie Sturd

Theses/Dissertations from 2023

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The Interface between Host and Bacterial Metabolism during Staphylococcus aureus Prosthetic Joint Infection, Blake P. Bertrand

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Investigating Transcriptional Anomalies During Persistence in Chlamydia trachomatis, Nathan D. Hatch

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Mechanisms of Mutated Myosin Vb Mediated Cholestasis in Microvillus Inclusion Disease, Melissa S. Holzapfel

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Investigating Host Cell Transcriptional Heterogeneity and Metabolism in Staphylococcus aureus Biofilm Infections, Christopher M. Horn

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Targeting the CXCR1/2 Axis in Pancreatic Ductal Adenocarcinoma, Caitlin Molczyk

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Synergetic Signaling Between the Chlamydia Secreted Effectors TarP and TmeA Regulates Actin Kinetics and Efficient Entry, Matthew Romero

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Investigating Plasmodial Proteostasis Mechanisms to Counter Artemisinin Resistance, Melissa Rosenthal

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Understanding the Effect of Chikungunya Virus Infection on Bone Homeostasis, Enakshi Roy

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Towards a Mode of Action for the Anti-Schistosomal Aryl Hydantoins, Thomas Schulze

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Investigating and Targeting Iron Metabolism in Pseudomonas Aeruginosa and Klebsiella Pneumoniae, Zachary Scott

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A Critical Assessment Of The Role Of ClpXP-Mediated Proteolysis In The Development and Differentiation Of Chlamydia trachomatis, Nicholas A. Wood

Theses/Dissertations from 2022

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Leukocyte Subsets in the Peripheral Blood and Spleen of Gastrointestinal Cancer Patients, Kathryn E. Cole

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Exploring Host-Pathogen Interactions of the Ebola Virus Ribonucleoprotein Complex, M. Jane Morwitzer

Investigating the Role of Sphingosine Kinases During Alphavirus Infection, Opeoluwa Oyewole

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Investigating the Role of Sphingosine Kinases During Alphavirus Infection, Opeoluwa Oyewole

Theses/Dissertations from 2021

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Role and Regulation of Staphylococcal Cell Death, Abdulelah Ahmed Alqarzaee S

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Metabolic heterogeneity and the roles of CodY and CcpA in central metabolism and S. aureus biofilm formation., Logan L. Bulock

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The Staphylococcus Aureus lrgAB Operon Encodes a Holin-Like Protein Involved in Pyruvate Transport, Jennifer L. Endres

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Neutrophils in Pancreatic Cancer Progression, Paran Goel

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Understanding the Impact of Chlamydia Trachomatis Infection on Host Vesicular Trafficking, Lisa M. Jorgenson

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Gene Expression Profiling of MAPK Pathway Inhibitor Resistance in Cutaneous Melanoma: Can Bioinformatics Be Used to Select Better Melanoma Cell Lines?, Stephen Luebker

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Humanized Mice for Brain Infection of Emerging Viruses, Edward Makarov

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Marinopyrrole Derivatives as Putative Antiparasitic Molecules Promoting Initiation of Programmed Cell Death in Toxoplasma gondii, Matthew C. Martens

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Role Of Endocytic Machinery Regulators in EGFR Traffic and Viral Entry, Insha Mushtaq

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Immunological Factors Associated with SIV/ SHIV Persistence in Diverse Tissue Niches, Omalla A. Olwenyi

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Characterization of Di-Aryl Urea Compounds Against Acute and Chronic Toxoplasma Gondii, Austin Sanford

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Molecular Pathogenesis of a Novel Subgroup of Peripheral T-cell Lymphomas, Jiayu Yu

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The Role of VGLL4 and MARK2-HDAC axis in Mitosis and Cancer, Yongji Zeng

Theses/Dissertations from 2020

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Fundamental differences in the B cell locus, V(D)J repertoire, and Marburg virus epitope recognition of the Egyptian rousette bat that may allow for asymptomatic presentation, Maggie Linn Bartlett

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Flavonoid and Cannabidiol Neural Glyoxalase Pathway Enhancement Against Aging and Alzheimer’s Disease, Joel R. Frandsen

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Multistrain HIV-1 Elimination: A CRISPR-Cas9 and Theranostics-based Approach, Jonathan Herskovitz

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Arginine Biosynthesis in Staphylococcus aureus, Itidal Reslane

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Glycan-dependent adherence and skin colonization of Staphylococcus epidermidis mediated by the surface protein Aap., Paroma Roy

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Identification of Clonal Evolution Pattern and Mutation Event Associated with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Using Next-Generation Sequencing, Cheng Wang

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Insights into the Chlamydial Niche: The Dynamic Roles of Inclusion Membrane (Inc) Proteins in Chlamydia trachomatis Development, Macy G. Wood

Theses/Dissertations from 2019

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The CXCR2-dependent role of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma, Mohammad Awaji

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Molecular Insights into Major Peripheral T-cell Lymphoma Entities with Advances in a Representative Model System, Tayla B. Heavican

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Mechanism of Bax/Bak Activation in Apoptotic Signaling, Kai Huang

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Role of Rac1-Pak pathway in aggressive b-cell lymphoma, Tian Tian

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IL-17-CXCR2 Axis Promotes Breast Cancer Metastasis and Therapy Resistance, Lingyun Wu

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Monocyte Anti-Inflammatory Activity Is Dictated by Metabolic Status during Staphylococcus Aureus Biofilm Infection, Kelsey J. Yamada

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Targeting Oncogenic Protein Sythesis in MYC-driven B Cell Lymphoma, Xuan Zhang

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Acid Resistance Mechanisms in Staphylococcus aureus, Chunyi Zhou

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The Role of Zyxin and LIMD1 in Mitosis and Cancer, Jiuli Zhou

Theses/Dissertations from 2018

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Francisella tularensis Insertion Sequence Elements Contribute to Differential Gene Expression, Amanda M. Bartling

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The Role of Hippo Pathway in Mitosis and Cancer, Xingcheng Chen

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Transcriptional regulation of icaADBC by IcaR and TcaR in Staphylococcus epidermidis, Tramy Hoang

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MicroRNA expression and disease correlation in a Hispanic Lupus cohort, Thandiwe Jere

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Dietary Polyunsaturated Fatty Acids Regulate Mammary Tumor Growth and Metastasis by Modulating Tissue Microenvironments, Saraswoti Khadge

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Elucidation of the functions of Neuropilin 2 in osteoclasts in promoting prostate cancer bone metastasis., Navatha S. Polavaram

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Regulation of Canonical and Non-Canonical Hippo Pathway Components in Mitosis and Cancer, Seth Stauffer

Theses/Dissertations from 2017

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Focus: A Graph Approach for Data-Mining and Domain-Specific Assembly of Next Generation Sequencing Data, Julia Sommer

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Redirection of the immune response to Staphylococcus aureus biofilm infection, Anna G. Staudacher

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Functional Importance of Proline Transporters in Staphylococcus aureus, Dianne L. Wellems

Theses/Dissertations from 2016

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Genetic Predisposition and M1 Macrophage Polarization Created by Elastin-Derived Peptides Drive Abdominal Aortic Aneurysm Formation, Matthew A. Dale

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The Role of Inflammatory Monocytes in Post-Influenza Methicillin-Resistant Staphylococcus aureus Pneumonia, Karl J. Fischer

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Amino Acid Catabolism in Staphylococcus aureus, Cortney Halsey

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Role of Stemloop D in Terminally Deleted Coxsackievirus B3 Replication, Lee K. Jaramillo

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The Pathogenesis of Natural Killer/T Cell Lymphoma, Bei Jiang

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Spatiotemporal Control of Staphylococcus aureus Biofilm Development, Derek E. Moormeier

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Recurrent Mutations of T-Cell Receptor and CO-Stimulatory Signaling Proteins in Peripheral T-Cell Lymphomas, Joseph Rohr

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Staphylococcus Aureus Biofilms Interfere With Macrophage Antimicrobial Responses Through Differential Gene Regulation, Toxin Production, and Purine Metabolism, Tyler D. Scherr

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Mutations Affecting Epigenetic Regulators and Their Role in Peripheral T-Cell Lymphomas, Chao Wang

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Regulation of cid-mediated cell death in Staphylococcus aureus, Ian H. Windham

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The Role of CBL Family of E3 Ubiquitin Ligases in Intestinal Epithelial Homeostasis, Neha Zutshi

Theses/Dissertations from 2015

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The cruicial role of the endocytic recyling regulator EHD1 in mammalian development, Sohinee Bhattacharyya

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Myeloid-derived suppressor cells contribute to the subversion of innate immunity during Staphylococcus aureus biofilm infection, Cortney E. Heim

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Pax5 negatively regulates B lineage cell proliferation through inhibition of D cyclin expression, Dallas Jones

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Molecular mechanism of LytSR signal transduction during biofilm formation, McKenzie Kristine Lehman

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Role of Macrophages in Muscle Transfection with pDNA/PLURONIC Formulation, Vivek Mahajan

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The Role of CXCR2 in Pancreatic Cancer Development and Progression, Abhilasha Purohit

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Characterization of the Replication of Coxsackievirus B3 with a Mutationally Disrupted CRE(2C) and the use of Creatinine-Hydrochloride as an Antibacterial Agent, Shane E. Smithee

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Identification of novel autoantibodies for lupus nephritis, Yinshi Yue

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Role of Hippo-YAP signaling in Mitosis and Prostate Cancer, Lin Zhang

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The Role of Genetic Alterations in Tumor Initiation, Progression and Transformation, Weiwei Zhang

Theses/Dissertations from 2014

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Detection of enteroviruses persistence in pancreas, spleen and heart, Abdulaziz Alhazmi

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Life or death: maintaining bacterial homeostatis, Casey Matthew Gries

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Staphylococcus epidermidis biofilm infection induces an anti-inflammatory response, Yenis Gutierrez-Murgas

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TP73 in non-hodgkin lymphoma pathogenesis and therapy, Hesham M. Hassan

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Characterization of influenza hemagglutinin vaccine immunogenicity and identification of novel anti-influenza therapeutics, Tess Kuenstling

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Analyses of the functional antibody repertoire in chronic HIV-infected individuals, Hongyan Liao

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Study of plasma cell repertoire in systemic lupus erythematosus and rheumatoid arthritis, Song Li

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Study of competence for DNA transformation in Staphylococcus aureus, Katherine Leanna Maliszewski

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Arginine Biosynthesis of Staphylococcus aureus, Austin S. Nuxoll

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Mechanistic insights into the metabolic basics of therapy resistance in pancreatic cancer, Vinee Purohit

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Contribution of Aap to Staphylococcus epidermidis virulence, Carolyn R. Schaeffer

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Aberrant microglia and inflammasome function in juvenile Batten Disease, Juan Xiong

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Novel phosphorylation of hippo-yap signaling pathway controls its oncogenic activity, Shuping Yang

Theses/Dissertations from 2013

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Regulation of rag-mediated V(D)J recombination and aberrant BCL2 to IGH translocation, Jirong Bai

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A conceptual framework for capture, retention and utilization of pathologist knowledge using whole slide imaging, Walter Scott Campbell

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On the identification of biologically relevant structures in aging and disease using systems biology and advanced network analysis, Kathryn M. Dempsey

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The ribonuclease RnpA is a novel target for antimicrobial development, Tess Marie Eidem

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Development and application of novel proteomic approaches for studying protein s-nitrosylation, Miao Liu

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Molecular regulation of bacterial genes by small RNA molecules during cellular growth phases, Eric W. Miller