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Theses/Dissertations from 2024

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Compensatory Changes in the Visual System as a Result of Neurodegeneration, Liz Bierlein

Theses/Dissertations from 2022

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Transcranial Direct Current Stimulation of Frontal/Occipital Cortices Modulates Neural Correlates of Cognition in Healthy Young Adults, Yasra Arif

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Astrocytic Contribution to Sensory Hypersensitivity in a Mouse Model of Fragile X Syndrome, Lara E. Bergdolt

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Fabrication and Characterization of Porous Biomaterial for Potential Antigen Delivery, Farah Shahjin

Theses/Dissertations from 2021

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Development of Long-Acting Antiviral Drug Nanoformulations, Denise Cobb

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Multimodal Neuroimaging of HIV and Aging, Brandon Lew

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In utero and Postnatal Oxycodone Exposure: Implications for Intergenerational Effects, Katherine E. Odegaard

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Neural Oscillatory Activity Serving Sensorimotor Control is Regulated by the Mitochondrial Redox Environment in Health and Disease, Rachel Spooner

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The Neurological Abnormalities of the Brain and Spinal Cord in Individuals with Cerebral Palsy, Michael Trevarrow

Theses/Dissertations from 2020

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Characterization of Novel Animal Models for Parkinson’s Disease, Mohannad Almikhlafi

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Dynamic Oscillatory Interactions Between Neural Attention and Sensorimotor Systems, Alex Wiesman

Theses/Dissertations from 2019

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Synthesis and Characterization of Long Acting Darunavir Prodrugs, Mary Banoub

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Mechanisms of calcium-dependent neurotransmission in photoreceptors, Justin J. Grassmeyer

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Synthesis and Characterization of Long-Acting Rilpivirine Prodrugs, James R. Hilaire

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Synthesis and Characterization of a Long-Acting Emtricitabine Prodrug Nanoformulation, Ibrahim M. Ibrahim

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Theranostics for Antiretroviral Biodistribution and Pharmacokinetics, Brendan M. Ottemann

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Development of a Long-Acting Nanoformulation of Dolutegravir for Prevention and Treatment of HIV-1 Infection, Brady Sillman

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Roles of autism gene ARID1B in murine brain development and behavior, Amanda L. Smith

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HIV-1 Elimination in Humanized Mice, Hang Su

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Human Immunodeficiency Virus Theranostics, Christopher J. Woldstad

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Novel antiviral effect of a small molecule ONC201 and its potential application in HIV-1 eradication, Runze Zhao

Theses/Dissertations from 2018

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Neural Correlates of Polysubstance Use: Differential and Interactive Effects of Alcohol and Cannabis on the Adolescent Brain, Joseph Aloi

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Neuronal and Glial Expression of GluN2C and GluN2D NMDA Receptor Subunit mRNA in Different Regions of the Mouse Forebrain, Hassan Alsaad

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Arid1b and Macf1 in Murine Brain Development and Behavior, Jeffrey Jay Moffat

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Properties of Synaptic Transmission from Rods and Cones in The Outer Plexiform Layer of The Vertebrate Retina, Xiangyi Wen

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T Cell Mediated Cytotoxicity in the MPTP Mouse Model of Parkinson's Disease, Rebecca A. Wilshusen

Theses/Dissertations from 2017

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Novel therapeutic approaches for Juvenile Neuronal Ceroid Lipofuscinosis (CLN3), Megan Elizabeth Bosch

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Development of Dual Reconstituted Humanized Mice for Studies of HIV-1 Neuropathogenesis, Weizhe Li

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Evaluation of Immune-Modulating Therapies For Parkinson's Disease, Katherine E. Olson

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Effects of GM-CSF on Dendritic Cells and Regulatory T cells in Parkinson’s Disease Patients and Models of Parkinson’s Disease, Charles Schutt

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Inflammasome Activation by Methamphetamine Potentiates Lipopolysaccharide Stimulation of IL-1β Production in Microglia, Enquan Xu

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A Role for δ-catenin in Synaptic Regulation, Li Yuan

Theses/Dissertations from 2016

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Molecular mechanisms involved in neurotoxicity mediated by HIV proteins and drug abuse, Yu Cai

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Expression and Function of Inflammation-Associated MicroRNAs in Traumatic Brain Injury, Emily Harrison

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Expression and Function of Inflammation-Associated MicroRNAs in Traumatic Brain Injury, Emily Brooke Harrison

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Target Validation and Pharmacological Characterization of Novel NMDAR Modulators, Kiran Sapkota

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Mechanisms of lateral-inhibitory feedback from horizontal cells to cone photoreceptors at the first synapse of the retina, Ted J. Warren

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The Role of Glutaminase and Extracellular Vesicles in Macrophages and Microglia, Beiqing Wu

Theses/Dissertations from 2015

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Compensatory Mechanisms and T Cell Migration In Mouse Models of Dopaminergic Loss, Kristi M. Anderson

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Development of Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Methods to Study Pathophysiology Underlying Neurodegenerative Diseases in Murine Models, Aditya N. Bade

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Acute Methamphetamine Exposure Affects Histone Modifying Enzymes and Cytokine Production in Macrophages, Ariel Burns

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Characteristics of Exocytosis and Endocytosis in Photoreceptors, Karlene M. Cork

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Targeted Magnetite Tissue Delivery for Antiretroviral Pharmacokinetics, Tianyuzi Li

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In vitro and in vivo evaluation of the nanoart carrying macrophage, Andrea L. Martinez-Skinner

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Cell-targeted antiretroviral nanoformulations: translational studies in mice, Pavan Puligujja

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The Role of Glutaminase 1 in HIV-1 Associated Neurocognitive Disorders and in Brain Development, Yi Wang

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CCR5 and the Blood Brain Barrier During HIV-1 Infection and Cell-Cell Communications, Shawna M. Woollard

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The Involvement of Let-7 miRNA in the Regulation of Retinal Progenitor Cells, Xiaohuan Xia

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ER stress mediated astrogliosis in HAND: involvement of IP3R2, Lu Yang

Theses/Dissertations from 2014

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Glyoxalase-1 gene transfer to prevent cerebral microvascular and neuronal dysfunctions in type 1 diabetes mellitus, Fadhel Ahmed M Alomar

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Vesicle exocytosis from rod photoreceptor synapses, Minghui Chen

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CXCR7 mediated neural progenitor cell migration and signaling in the absence of CXCR4, Qiang Chen

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Dysregulation of brain metabolism during human immunodeficiency virus neuropathology in humanized mice, Adrian A. Epstein

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Bioinformatics analyses of macrophage transcriptome profiles following HIV infection, cart and meth treatments, Danielle S. Fenster

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Proteomic alterations of the macrophage following HIV-1 infection and methamphetamine exposure, Nicole A. Haverland

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Mitochondria and autophagy in neurodegeration, Phillip Ryan Purnell

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The role of mitochondria in the pathogenesis of neurodegenerative diseases, Lance Michael Villeneuve

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Characterization and regulation of nanoART endosomal trafficking, Gang Zhang

Theses/Dissertations from 2013

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Inflammatory factors reduce neuronal autophagy, Carly Bycenski

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Role of microrna-142 in human immunodeficiency virus 1- associated neurocognitive disorders, Amrita Datta Chaudhuri

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Role of the inflammasome in the pathogenesis and immune responses to staphylococcus aureus infection in the central nervous system, Richa Hanamsagar

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Immune modulation for parkinson's disease, Lisa Kosloski-Bilek

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Reactive carbonyl species and complications in diabetes mellitus, Caronda J. Moore

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Nanozymes for the delivery of superoxide dismutase 1 to the brain, Poornima Suresh

Theses/Dissertations from 2012

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Immunophenotyping, behavior and therapeutic efficacy testing in experimental models and in parkinson's disease, Saunders Jessica AL Hutter

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Neuroimmune regulation in models of neurodegenerative diseases, David K. Stone

Theses/Dissertations from 2011

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HIV-1 clades B and C infection disparity in macropages: potential relevance to HIV-1 neuropathogenesis, Agnes Alicia Constantino-Rodriguez

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Epidermal growth factor receptor activation and regulation by an aqueous extract of hogbarn dust, Puttappa Rachappa Dodmane

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Dynamics of the monocyte-macrophage proteome during differentiation and HIV-1 infection, Stephanie D. Kraft-Terry

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Architecture of the photoreceptor ribbon synapse: L-type voltage-gated calcium channel mobility and the role of cholesterol in neurotransmission, Aaron Jeffrey Mercer

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Development of a macrophage-mediated delivery system for crystalline antiretroviral nanoparticles, Ari S. Nowacek

Theses/Dissertations from 2010

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Synaptic strength at the photoreceptor ribbon synapse: vesicle pools, calcium channel number and vesicular glutamate concentration, Theodore Michael Bartoletti

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In vivo characterization of tau-tubulin kinase 1 in neurocognitive impairment and neurodegeneration, Jiqing Xu

Theses/Dissertations from 2009

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Molecular regulators of HIV-1 pathogenesis, Sugato Banerjee

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Development of adjunctive therapies for HIV-1- associated dementia, Dawn L. Eggert

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Identification of NMDA receptor subunit NR2D-association proteins implications for synaptic plasticity and excitotoxicity, Vivek Gautam

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Binding and functional properties of the Alpha-2c-Del322-325 adrenergic receptor polymorphism, Megan Danielle Montgomery

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Cross-talk between CAMP/PKA and GSK3ß, Lynn Roy

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The role of calcium-permeable AMPA receptors containing Q/R-Unedited Glur2 subunits in neurogenesis, Nicholas Paul Whitney

Theses/Dissertations from 2008

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Nitrosylative and oxidative regulation of insulin-degrading enzyme, Crystal Marie Cordes

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Brain inflammmation and glutaminase-mediated excitotoxicity in HIV-1-associated dementia, Nathan Erdmann

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Investigation of human immune deficiency virus type 1 mechanisms of immune escape during infection of monocyte-derived macrophages, Irena Kadiu

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Characterization of animal behavioral models using juvenile rats for screeing pediatric antidepressant efficacy, Abbey Lea Reed

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Development of immune-mediated vaccine strategies for Parkinson's disease, Ashley D. Reynolds

Theses/Dissertations from 2007

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Altered regulation of N-Methyl-D-Aspartate (NMDA) receptors in the diabetic rat brain, LeDon Bean

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The NMDA receptor subunit 2D carboxy terminal : a molecular scaffold for intracellular signaling proteins, Jeffrey W. Boyle

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TIMP-1 regulation in astrocytes : implications for HIV-1-associated dementia, Jessica Gardner

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The Signaling and apoptotic effects of TNF-related apoptosis-inducing ligand in HIV-1 associated dementia, Yunlong Huang

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Regulation of epidermal growth factor receptors and mitogenic signaling by lysophosphatidic acid and beta-2 adrenergic receptors in airway cells, Karen Marie Kassel

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Antidepressant regulation of brain-derived neurotrophic factor and its receptor in rats, Megan Elizabeth Kozisek

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ATP and neuropeptide y regulation of bovine chromaffin cell, Toni Marie Luke

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Role of the ERK 1/2 MAP kinase pathway on the celluar response to anticancer chemotherapy, Scott Michael Stoeger

Theses/Dissertations from 2004

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The Regulation of MU Opioid receptor signal transduction by the accessory protein ranbpm, Jeffery Neil Talbot

Theses/Dissertations from 2003

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Phenotypic rescue of the reduced folate carrier knockout mouse, Steven Eugene-Lee Heller

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Molecular mechanisms involved in alpha1B-adrenergic receptor sequestration, endocytosis, down-regulation and up-regulation, Steven Craig Prinster

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Noradrenergic regulation of the developing brain, Jeff Sanders

Theses/Dissertations from 2002

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Interactions between the guanine nucleotide exchange factor, VAV2, the platelet-derived growth factor receptor-beta and phosphoinositide 3-kinase in coronary artery vascular smooth muscle cells : functional implications in atherosclerosis, Allison M. Cushman-Vokoun

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Transcriptional and translational regulation of the human rasGAP gene, Jason Glanzer

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Characterization of insulin receptor signaling pathways that mediate potentiation of NMDA receptor activity, Donald Albert Skifter

Theses/Dissertations from 2001

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Signaling in vascular smooth muscle cells by homocysteine, James C. Brown