Using LC-MS/MS Metabolomics to Study Cancer Metabolism

Title

Using LC-MS/MS Metabolomics to Study Cancer Metabolism

Files

Download Troy Robertson and Marshall Dawkins Original Presentation File (368 KB)

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Publication Date

Summer 8-6-2020

College, Institute, or Department

Eppley Institute for Research in Cancer

Faculty Mentor

Pankaj Singh

Research Mentor

Nick Mullen

Document Type

Poster

Abstract

Using LC-MS/MS, we found that pancreatic cancer proliferation can be slowed down using the drug Brequinar as a DHODH inhibitor, which reduces the number of metabolites necessary to create pyrimidines and allow proliferation.

Keywords

LC-MS/MS, Metabolomics, Cancer

Using LC-MS/MS Metabolomics to Study Cancer Metabolism

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