Using LC-MS/MS Metabolomics to Study Cancer Metabolism
Download Troy Robertson and Marshall Dawkins Original Presentation File (368 KB)
College, Institute, or Department
Eppley Institute for Research in Cancer
Using LC-MS/MS, we found that pancreatic cancer proliferation can be slowed down using the drug Brequinar as a DHODH inhibitor, which reduces the number of metabolites necessary to create pyrimidines and allow proliferation.
LC-MS/MS, Metabolomics, Cancer
Robertson, Troy; Dawkins, Marshall; Mullen, Nick; and Singh, Pankaj, "Using LC-MS/MS Metabolomics to Study Cancer Metabolism" (2020). Posters: 2020 Summer Undergraduate Research Program. 12.