GlyKali : an efficient means of harnessing study-specific glycan and glycosylation data
Download Ashdyn Anderson Original Presentation File (183 KB)
College, Institute, or Department
Cellular & Integrative Physiology
Rebekah L. Gundry
Maia Kelly, Christopher Ashwood
Glycosylation is an enzyme directed form of secondary protein modification in eukaryotic and archaeal cell.Glycosylation plays a critical role in determining proteins three-dimensional configuration and structure, function, and stability.
A glycan, or polysaccharide, is a chain like structure containing a number of monosaccharides. Glycans make up Glycoconjugates to makeup the glycoproteins that cover the cell and makeup a cell-surface glycome.
The way these glycan chains are glycosylated has been known to change due to immune responses and disease. For example, Blood Type is known to be a result of differential cell-surface glycomes.
The goal of this workflow is as follows. To simplify mass data retrieval of glycomic data Use already known data from databases in context of experimental data.
GlyKali, Glycan, Glycosylation
Anderson, Ashdyn; Kelly, Maia; and Gundry, Rebekah, "GlyKali : an efficient means of harnessing study-specific glycan and glycosylation data" (2020). Posters: 2020 Summer Undergraduate Research Program. 9.