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Presentation date

Summer 8-12-2021

College, Institute, or Department

Radiation Oncology

Faculty Mentor

Dinah Clark

Research Mentor

Dandan Zheng

Abstract

Radiogenomics is a fusion of two methods, radiomics, and genomics. Radiomics is the process in which features are extracted from medical images such as MRIs, CT scans, and PET scans. Genomics on the other hand is studying an organism's genome and, in this study, their respective gene mutations. By combining both methods, radiogenomics can help find biomarkers for various cancers to help diagnose and treat patients more efficiently. In this study, Radiogenomics was used to find an association between genomic profiles and imaging features of patients with pancreatic ductal adenocarcinoma (PDAC). Out of a total of 117 patients available, only 29 patients were selected for the study. The study required that the patients must have a complete genetic profile available, a preoperative CT scan, PDAC, and are participating in the Rapid Autopsy Program (RAP).

Keywords

Radiogenomics, Pancreatic cancer, radiomics, genomics

Radiogenomics: Combining SNP Studies with Pancreatic Ductal Adenocarcinoma Medical Images

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