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Theses/Dissertations from 2013

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Pancreatic cancer-associated miRNAs : expression, regulation and function, Ashley M. Mohr

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Mechanistic studies of mitochondrial outer membrane permeabilization (MOMP), Xiaming Pang

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Novel roles for JAK2/STAT5 signaling in mammary gland development, cancer, and immune dysregulation, Jeffrey Wayne Schmidt

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Optimization of therapeutics against lethal pancreatic cancer, Joshua J. Souchek

Theses/Dissertations from 2012

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Immune-based novel diagnostic mechanisms for pancreatic cancer, Michael J. Baine

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Sox2 associated proteins are essential for cell fate, Jesse Lee Cox

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KSR2 regulates cellular proliferation, transformation, and metabolism, Mario R. Fernandez

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Discovery of a novel signaling cross-talk between TPX2 and the aurora kinases during mitosis, Jyoti Iyer

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Regulation of metabolism by KSR proteins, Paula Jean Klutho

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The role of ERK 1/2 signaling in the dna damage-induced G2, Ryan Kolb

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Regulation of the Bcl-2 family network during apoptosis induced by different stimuli, Hernando Lopez

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Studies on the role of cullin3 in mitosis, Saili Moghe

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Characteristics of amyloid precursor-like protein 2 (APLP2) in pancreatic cancer and Ewing's sarcoma, Haley Louise Capek Peters

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Structural and biophysical analysis of a human inosine triphosphate pyrophosphatase polymorphism, Peter David Simone

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Functions and regulation of Ron receptor tyrosine kinase in human pancreatic cancer and its therapeutic applications, Yi Zou

Theses/Dissertations from 2011

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Coordinate detection of new targets and small molecules for cancer therapy, Kurt Fisher

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The role of c-Myc in pancreatic cancer initiation and progression, Wan-Chi Lin

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The role of inosine triphosphate pyrophosphatase (ITPA) in maintanence [sic] of genomic stability in human cells, Miriam-Rose Menezes

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Molecular insights into major histocompatibility complex class I folding and assembly, Laura Christina Simone

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The role of bcl-2 in colon cancer metastatic progression, Wang Wang

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A rational peptidomimetic approach towards generation of high affinity BRCT (BRCA1) inhibitors, Ziyan Yuan

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D-type cyclins and breast cancer, Quian Zhang

Theses/Dissertations from 2010

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Cell survival and metastasis regulation by TGFß/PKA signaling, Sanjib Chowdhury

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Cyclin dependent kinase 5 contributes to the progression of pancreatic cancer, John Eggers

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Roles of XPF-ERCC1 in dna repair, Laura A. Fisher

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Cell cycle control and spatio-temporal regulation of erk signaling by ksr1, Heidi Jo Johnson

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Regulation and function of Oct-3/4 and Sox2 in embryonal carcinoma and embryonic stem cells, Sunil Kumar Mallanna

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Binding studies of human single-stranded dna binding and repair proteins : replication protein A and RAD52, Aishwarya Prakash

Theses/Dissertations from 2009

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Advances in the in vitro study of Huntinton's Disease mutagenesis and pathogenesis, David Alan Claassen

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The role of signal transducer and activator of transcription 5 (Stat5) in mammary gland development and tumorigenesis, Bradley Allen Creamer

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Tumor-stromal interactions mediated by paracrine hedgehog signaling in pancreatic cancer, Jennifer M Bailey Lundberg

Theses/Dissertations from 2008

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Regulation of cellular metabolism and cell motility by KSR, Matthew B. Boehm

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Studies on p120-catenin: the regulatory or phosphorylation domain of p120-catenin controls E-cadherin dynamics at the plasma membrane, Yuri Fukumoto

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Structure-function analysis of the apoptosis gateway protein bax, Nicholas M. George

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Immune recognition of breast tumor cells, Xuede Lin

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Cell cycle checkpoint and other trans-factors influence trinucleotide repeat instability in saccharomyces cerevisiae, David F. Razidlo

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The role of a-family DNA polymerases in DNA interstrand cross-link repair, Laura R. Zietlow

Theses/Dissertations from 2006

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Rev1 modulates trinucleotide repeat instability in saccharomyces cerevisiae, Natasha Collins