Document Type
Article
Journal Title
International Journal of Chronic Obstructive Pulmonary Disease
Publication Date
2018
Volume
13
Abstract
BACKGROUND: COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE™) uses five questions and peak expiratory flow (PEF) thresholds (males ≤350 L/min; females ≤250 L/min) to identify patients with a forced expiratory volume in 1 second (FEV
METHODS: Data from the CAPTURE development study were used to test its sensitivity (SN) and specificity (SP) differentiating mild-to-moderate COPD (n=73) from no COPD (n=87). SN and SP for differentiating all COPD cases (mild to severe; n=259) from those without COPD (n=87) were also estimated. The modified Medical Research Council (mMRC) dyspnea scale and COPD Assessment Test (CAT™) were used to evaluate symptoms and health status. Clinical Trial Registration: NCT01880177, https://ClinicalTrials.gov/ct2/show/NCT01880177?term=NCT01880177&rank=1.
RESULTS: Mean age (+SD): 61 (+10.5) years; 41% male. COPD: FEV
CONCLUSION: CAPTURE (450/350) may be useful for identifying symptomatic patients with mild-to-moderate airflow obstruction in need of diagnostic evaluation for COPD.
MeSH Headings
Aged, Aged, 80 and over, Case-Control Studies, Cross-Sectional Studies, Disease Progression, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Prospective Studies, Pulmonary Disease, Chronic Obstructive, Sensitivity and Specificity, Surveys and Questionnaires, Symptom Assessment, Vital Capacity
DOI Link
ISSN
1178-2005
Creative Commons License
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Recommended Citation
Leidy, Nancy K.; Martinez, Fernando J.; Malley, Karen G.; Mannino, David M.; Han, MeiLan K.; Bacci, Elizabeth D.; Brown, Randall W.; Houfek, Julia F.; Labaki, Wassim W.; Make, Barry J.; Meldrum, Catherine A.; Quezada, Wilson; Rennard, Stephen I.; Thomashow, Byron; and Yawn, Barbara P., "Can CAPTURE Be Used to Identify Undiagnosed Patients with Mild-to-Moderate COPD Likely to Benefit from Treatment?" (2018). Journal Articles: Pulmonary & Critical Care Med. 42.
https://digitalcommons.unmc.edu/com_pulm_articles/42
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