Submissions from 2025
Electronic and Regular Cigarettes Induce Transcriptional and Physiological Changes in Cardiomyocytes, Hesham Basma, Kajari Dhar, Jason Payne, Stephen I. Rennard, and Brian D. Lowes
Gallium β-Cyclodextrin Nanoparticles Containing both Gallium Protoporphyrin and Gallium Nitrate Exhibit Antimicrobial Activity against Nontuberculous Mycobacteria in Vitro and in Vivo, Seoung-Ryoung Choi, Bradley E. Britigan, and Prabagaran Narayanasamy
Editing Approaches to Treat Alpha-1 Antitrypsin Deficiency, Derek M. Erion, Leah Y. Liu, Christopher R. Brown, Stephen I. Rennard, and Humam Farah
Zinc Promotes Mitochondrial Health Through PGC-1alpha Enhancing Bacterial Clearance in Macrophages Infected with Mycobacterium avium Complex, Ruxana Sadikot, Prabagaran Narayanasamy, Zhihong Yuan, Deandra R. Smith, and Daren L. Knoell
Submissions from 2024
Polygenic and Transcriptional Risk Scores Identify Chronic Obstructive Pulmonary Disease Subtypes in the COPDGene and ECLIPSE Cohort Studies, Matthew Moll, Julian Hecker, John Platig, Jingzhou Zhang, Auyon J. Ghosh, Katherine A. Pratte, Rui-Sheng Wang, Davin Hill, Iain R. Konigsberg, Joe W. Chiles, Craig P. Hersh, Peter J. Castaldi, Kimberly Glass, Jennifer G. Dy, Don D. Sin, Ruth Tal-Singer, Majd Mouded, Stephen I. Rennard, Gary P. Anderson, Gregory L. Kinney, Russell P. Bowler, Jeffrey L. Curtis, Merry-Lynn McDonald, Edwin K. Silverman, Brian D. Hobbs, and Michael H. Cho
Lung-Delivered IL-10 Therapy Elicits Beneficial Effects via Immune Modulation in Organic Dust Exposure-Induced Lung Inflammation, Aaron D. Schwab, Todd A. Wyatt, Amy J. Nelson, Angela Gleason, Rohit Gaurav, Debra J. Romberger, and Jill A. Poole
Targeting Transitioning Lung Monocytes/Macrophages as Treatment Strategies in Lung Disease Related to Environmental Exposures, Aaron Schwab, Todd A. Wyatt, Grace Moravec, Geoffrey M. Thiele, Amy J. Nelson, Angela Gleason, Oliver Schanze, Michael J. Duryee, Debra J. Romberger, Ted R. Mikuls, and Jill A. Poole
Submissions from 2023
Agricultural Dust Derived Bacterial Extracellular Vesicle Mediated Inflammation is Attenuated by DHA, Art J. Heires, Derrick R. Samuelson, Daniel Villageliu, Tara M. Nordgren, and Debra J. Romberger
Longitudinal Assessment of Multimorbidity Medication Patterns among Smokers in the COPDGene Cohort, Yisha Li, Sarah J. Schmiege, Heather Anderson, Nicole E. Richmond, Kendra A. Young, John E. Hokanson, Stephen I. Rennard, Tessa L. Crume, Erin Austin, Katherine A. Pratte, Rebecca Conway, and Gregory L. Kinney
Icenticaftor, Novel Therapy for COPD: This Glass Is Half Full, Stephen I. Rennard
Submissions from 2022
Relationships of Serum CC16 Levels with Smoking Status and Lung Function in COPD, Kelli C. Gribben, Jill A. Poole, Amy J. Nelson, Paraskevi A. Farazi, Christopher S. Wichman, Art J. Heires, Debra J. Romberger, and Tricia D. LeVan
Identifying Individual Medications Affecting Pulmonary Outcomes When Multiple Medications are Present, Yisha Li, Ran Dai, Yeongjin Gwon, Stephen I. Rennard, Barry J. Make, Dinah Foer, Matthew J. Strand, Erin Austin, Kendra A. Young, John E. Hokanson, Katherine A. Pratte, Rebecca Conway, Gregory L. Kinney, and COPDGene investigators
Updated Perspectives on the Role of Biomechanics in COPD: Considerations for the Clinician, Jennifer M. Yentes, Wai-Yan Liu, Kuan Zhang, Eric Markvicka, and Stephen I. Rennard
Submissions from 2021
Genetic Variation in Genes Regulating Skeletal Muscle Regeneration and Tissue Remodelling Associated with Weight Loss in Chronic Obstructive Pulmonary Disease, Preeti Lakshman Kumar; Ava C. Wilson; Alison Rocco; Michael H. Cho; Emily Wan; Brian D. Hobbs; George R. Washko; Victor E. Ortega; Stephanie A. Christenson; Xingnan Li; J. Michael Wells; Surya P. Bhatt; Dawn L. DeMeo; Sharon M. Lutz; Harry Rossiter; Richard Casaburi; Stephen I. Rennard; David A. Lomas; Wassim W. Labaki; Ruth Tal-Singer; Russel P. Bowler; Craig P. Hersh; Hemant K. Tiwari; Mark Dransfield; Anna Thalacker-Mercer; Deborah A. Meyers; Edwin K. Silverman; Merry-Lynn N. McDonald; and COPDGene, ECLIPSE and SPIROMICS investigators
Latent Traits of Lung Tissue Patterns in Former Smokers Derived by Dual Channel Deep Learning in Computed Tomography Images, Frank Li, Jiwoong Choi, Chunrui Zou, John D. Newell, Alejandro P. Comellas, Chang Hyun Lee, Hongseok Ko, R. Graham Barr, Eugene R. Bleecker, Christopher B. Cooper, Fereidoun Abtin, Igor Barjaktarevic, David Couper, MeiLan Han, Nadia N. Hansel, Richard E. Kanner, Robert Paine, Ella A. Kazerooni, Fernando J. Martinez, Wanda O'Neal, Stephen I. Rennard, Benjamin M. Smith, Prescott G. Woodruff, Eric A. Hoffman, and Ching-Long Lin
Small Airway Determinants of Airflow Limitation in Chronic Obstructive Pulmonary Disease, Vasiliy V. Polosukhin, Sergey S. Gutor, Rui-Hong Du, Bradley W. Richmond, Pierre P. Massion, Pingsheng Wu, Justin M. Cates, Kim L. Sandler, Stephen I. Rennard, and Timothy S. Blackwell
The Effect of Long-Acting Dual Bronchodilator Therapy on Exercise Tolerance, Dynamic Hyperinflation, and Dead Space during Constant Work Rate Exercise in COPD, William W. Stringer, Janos Porszasz, Min Cao, Harry B. Rossiter, Shahid Siddiqui, Stephen I. Rennard, and Richard Casaburi
Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS), Chunrui Zou, Frank Li, Jiwoong Choi, Babak Haghighi, Sanghun Choi, Prathish K. Rajaraman, Alejandro P. Comellas, John D. Newell, Chang Hyun Lee, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Meilan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric C. Kleerup, Fernando J. Martinez, Wanda O'Neal, Robert Paine, Stephen I. Rennard, Benjamin M. Smith, Prescott G. Woodruff, Eric A. Hoffman, and Ching-Long Lin
Submissions from 2020
Current Smoking With or Without Chronic Bronchitis is Independently Associated with Goblet Cell Hyperplasia in Healthy Smokers and COPD Subjects, Victor Kim, Stephanie Jeong, Huaqing Zhao, Mehmet Kesimer, Richard C. Boucher, J. Michael Wells, Stephanie A. Christenson, MeiLan K. Han, Mark Dransfield, Robert Paine, Christopher B. Cooper, Igor Barjaktarevic, Russell Bowler, Jeffrey L. Curtis, Robert J. Kaner, Sarah L. O'Beirne, Wanda K. O'Neal, Stephen I. Rennard, Fernando J. Martinez, and Prescott G. Woodruff
Improving the evaluation of COPD exacerbation treatment effects by accounting for early treatment discontinuations: a post-hoc analysis of randomized clinical trials., Agnieszka Król, Robert Palmér, Virginie Rondeau, Stephen I. Rennard, Ulf G. Eriksson, and Alexandra Jauhiainen
Co-Morbidity Patterns Identified Using Latent Class Analysis of Medications Predict All-Cause Mortality Independent of Other Known Risk Factors: The COPDGene® Study, Yisha Li, Margaret Ragland, Erin Austin, Kendra Young, Katherine Pratte, John E. Hokanson, Terri H Beaty, Elizabeth A. Regan, Stephen I. Rennard, Christina Wern, Michael R. Jacobs, Ruth Tal-Singer, Barry J. Make, Gregory L. Kinney, and COPDGene investigators
Agonist-Specific Desensitization of PGE2-Stimulated cAMP Signaling Due to Upregulated Phosphodiesterase Expression in Human Lung Fibroblasts, Francisco J. Nunez, Nancy Schulte, David M. Fogel, Joel Michalski, Stephen I. Rennard, Raymond B. Penn, Myron L. Toews, and Rennolds S. Ostrom
Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease, Dave Singh, Mona Bafadhel, Christopher E. Brightling, Frank C. Sciurba, Jeffrey L. Curtis, Fernando J. Martinez, Cara B. Pasquale, Debora D. Merrill, Norbert Metzdorf, Stefano Petruzzelli, Ruth Tal-Singer, Christopher Compton, Stephen I. Rennard, and Ubaldo J. Martin
Heme Metabolism Genes Downregulated in COPD Cachexia, Ava C. Wilson, Preeti L. Kumar, Sool Lee, Margaret M. Parker, Itika Arora, Jarrett D. Morrow, Emiel F.M. Wouters, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Alvar Agusti, Ruth Tal-Singer, Mark T. Dransfield, J. Michael Wells, Surya P. Bhatt, George Washko, Victor J. Thannickal, Hemant K. Tiwari, Craig P. Hersh, Peter J. Castaldi, Edwin K. Silverman, and Merry-Lynn N. McDonald
Submissions from 2019
TGF-β Induces a Heart Failure Phenotype via Fibroblasts Exosome Signaling, Hesham Basma, Adelaide N. Johanson, Kajari Dhar, Daniel R. Anderson, Fang Qiu, Stephen I. Rennard, and Brian D. Lowes
Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS), Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell, Chang Hyun Lee, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Mei Lan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric A.C. Kleerup, Fernando J. Martinez, Wanda O'Neal, Robert Paine, Stephen I. Rennard, Benjamin M. Smith, Prescott G. Woodruff, and Ching-Long Lin
Bronchoalveolar Lavage Fluid from COPD Patients Reveals More Compounds Associated with Disease than Matched Plasma, Eitan Halper-Stromberg, Lucas Gillenwater, Charmion Cruickshank-Quinn, Wanda Kay O'Neal, Nichole Reisdorph, Irina Petrache, Yonghua Zhuang, Wassim W. Labaki, Jeffrey L. Curtis, James Wells, Stephen I. Rennard, Katherine A. Pratte, Prescott Woodruff, Kathleen A. Stringer, Katerina Kechris, and Russell P. Bowler
It's More Than Low BMI: Prevalence of Cachexia and Associated Mortality in COPD, Merry-Lynn N. McDonald, Emiel F.M. Wouters, Erica Rutten, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Marcas Bamman, Bartolome Celli, Alvar Agusti, Ruth Tal-Singer, Craig P. Hersh, Mark Dransfield, and Edwin K. Silverman
Prospective Observational Study in Patients with Obstructive Lung Disease: NOVELTY Design, Helen K. Reddel, Maria Gerhardsson de Verdier, Alvar Agustí, Gary Anderson, Richard Beasley, Elisabeth H. Bel, Christer Janson, Barry Make, Richard J. Martin, Ian Pavord, David Price, Christina Keen, Asparuh Gardev, Stephen I. Rennard, Alecka Sveréus, Aruna T. Bansal, Lance Brannman, Niklas Karlsson, Javier Nuevo, Fredrik Nyberg, Simon S. Young, and Jørgen Vestbo
Submissions from 2018
Centrilobular Emphysema and Coronary Artery Calcification: Mediation Analysis in the SPIROMICS Cohort, Surya P. Bhatt, Hrudaya P. Nath, Young-Il Kim, Rekha Ramachandran, Jubal R. Watts, Nina L.J. Terry, Sushil Sonavane, Swati P. Deshmane, Prescott G. Woodruff, Elizabeth C. Oelsner, Sandeep Bodduluri, MeiLan K. Han, Wassim W. Labaki, J. Michael Wells, Fernando J. Martinez, R. Graham Barr, Mark T. Dransfield, and SPIROMICS investigators
Imaging-Based Clusters in Current Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS), Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Mei Lan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric A.C. Kleerup, Fernando J. Martinez, Wanda O'Neal, Stephen I. Rennard, Prescott G. Woodruff, and Ching-Long Lin
Can CAPTURE Be Used to Identify Undiagnosed Patients with Mild-to-Moderate COPD Likely to Benefit from Treatment?, Nancy K. Leidy, Fernando J. Martinez, Karen G. Malley, David M. Mannino, MeiLan K. Han, Elizabeth D. Bacci, Randall W. Brown, Julia F. Houfek, Wassim W. Labaki, Barry J. Make, Catherine A. Meldrum, Wilson Quezada, Stephen I. Rennard, Byron Thomashow, and Barbara P. Yawn
The Development of AZD7624 for Prevention of Exacerbations in COPD: A Randomized Controlled Trial, Naimish R. Patel, Danen M. Cunoosamy, Malin Fagerås, Ziad Taib, Sara Asimus, Tove Hegelund-Myrbäck, Sofia Lundin, Katerina Pardali, Nisha Kurian, Eva Ersdal, Cecilia Kristensson, Katarina Korsback, Robert Palmér, Mary N. Brown, Steven Greenaway, Leonard Siew, Graham W. Clarke, Stephen I. Rennard, Barry J. Make, Robert A. Wise, and Paul Jansson
Use of a 4-Week Up-Titration Regimen of Roflumilast in Patients with Severe COPD, Henrik Watz, Nitin Bagul, Klaus F. Rabe, Stephen I. Rennard, Vijay Kt Alagappan, Jonas Román, Axel Facius, and Peter Ma Calverley
Submissions from 2017
Variability in Objective and Subjective Measures Affects Baseline Values in Studies of Patients with COPD, Wayne H. Anderson, Jae Wook Ha, David J. Couper, Wanda K. O'Neal, R. Graham Barr, Eugene R. Bleecker, Elizabeth E. Carretta, Christopher B. Cooper, Claire M. Doerschuk, M. Bradley Drummond, MeiLan K. Han, Nadia N. Hansel, Victor Kim, Eric C. Kleerup, Fernando J. Martinez, Stephen I. Rennard, Donald Tashkin, Prescott G. Woodruff, Robert Paine, Jeffrey L. Curtis, Richard W. Kanner, and SPIROMICS Research Group
Reduced MicroRNA-503 Expression Augments Lung Fibroblast VEGF Production in Chronic Obstructive Pulmonary Disease, Jun Ikari, Amy J. Nelson, Jannah Obaid, Alvaro Giron-Martinez, Kumiko Ikari, Fumihiko Makino, Shunichiro Iwasawa, Yoko Gunji, Maha Farid, Xingqi Wang, Hesham Basma, Dawn Demeo, Carol Feghali-Bostwick, Olaf Holz, Klaus Rabe, Xiangde Liu, and Stephen I. Rennard
Body Mass Index Change in Gastrointestinal Cancer and Chronic Obstructive Pulmonary Disease is Associated with Dedicator of Cytokinesis 1, Merry-Lynn Noelle McDonald, Sungho Won, Manuel Mattheisen, Peter J. Castaldi, Michael H. Cho, Erica Rutten, Megan Hardin, Wai-Ki Yip, Stephen I. Rennard, David A. Lomas, Emiel F.M. Wouters, Alvar Agusti, Richard Casaburi, Christoph P. Lange, George O'Connor, Craig P. Hersh, and Edwin K. Silverman
Network-Based Analysis Reveals Novel Gene Signatures in Peripheral Blood of Patients with Chronic Obstructive Pulmonary Disease, Ma'en Obeidat, Yunlong Nie, Virginia Chen, Casey P. Shannon, Anand Kumar Andiappan, Bernett Lee, Olaf Rotzschke, Peter J. Castaldi, Craig P. Hersh, Nick Fishbane, Raymond T. Ng, Bruce McManus, Bruce E. Miller, Stephen I. Rennard, Peter D. Paré, and Don D. Sin
Effect of low-level CO2 on innate inflammatory protein response to organic dust from swine confinement barns., David Schneberger, Jane M. DeVasure, Kristina L. Bailey, Debra J. Romberger, and Todd A. Wyatt
Effect of low-level CO2 on innate inflammatory protein response to organic dust from swine confinement barns., David Schneberger, Jane M. DeVasure, Kristina L. Bailey, Debra J. Romberger, and Todd A. Wyatt
Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression., Zhi Tian, Hui Zhang, Jendayi Dixon, Nicole Traphagen, Todd A. Wyatt, Kusum K. Kharbanda, Samantha Simet, Narasaiah Kolliputi, and Diane S Allen-Gipson
Submissions from 2016
Effect of Tiotropium on Night-Time Awakening and Daily Rescue Medication Use in Patients with COPD, Peter M.A. Calverley, Stephen I. Rennard, Emmanuelle Clerisme-Beaty, Norbert Metzdorf, Valentina Bayer Zubek, and Richard ZuWallack
Interpreting Patient-Reported Outcomes from Clinical Trials in COPD: A Discussion, Paul W. Jones, Stephen I. Rennard, Maggie Tabberer, John H. Riley, Mitra Vahdati-Bolouri, and Neil C. Barnes
COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry, Janice M. Leung, Virginia Chen, Zsuzsanna Hollander, Darlene Dai, Scott J. Tebbutt, Shawn D. Aaron, Kathy L. Vandemheen, Stephen I. Rennard, J. Mark FitzGerald, Prescott G. Woodruff, Stephen C. Lazarus, John E. Connett, Harvey O. Coxson, Bruce Miller, Christoph Borchers, Bruce M. McManus, Raymond T. Ng, and Don D. Sin
Effects of Roflumilast in COPD Patients Receiving Inhaled Corticosteroid/Long-Acting β2-Agonist Fixed-Dose Combination: RE(2)SPOND Rationale and Study Design, Stephen I. Rennard, Fernando J. Martinez, Klaus F. Rabe, Sanjay Sethi, Emilio Pizzichini, Andrew McIvor, Shahid Siddiqui, Antonio Anzueto, and Haiyuan Zhu
Upregulation of RGS2: A New Mechanism for Pirfenidone Amelioration of Pulmonary Fibrosis, Yan Xie, Haihong Jiang, Qian Zhang, Suneet Mehrotra, Peter W. Abel, Myron L. Toews, Dennis W. Wolff, Stephen I. Rennard, Reynold A. Panettieri, Thomas B. Casale, and Yaping Tu
Submissions from 2015
Design of a Multi-Center Immunophenotyping Analysis of Peripheral Blood, Sputum and Bronchoalveolar Lavage Fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS), Christine M. Freeman, Sean Crudgington, Valerie R. Stolberg, Jeanette P. Brown, Joanne Sonstein, Neil E. Alexis, Claire M. Doerschuk, Patricia V. Basta, Elizabeth E. Carretta, David J. Couper, Annette T. Hastie, Robert J. Kaner, Wanda K. O'Neal, Robert Paine, Stephen I. Rennard, Daichi Shimbo, Prescott G. Woodruff, Michelle Zeidler, and Jeffrey L. Curtis
Identifying Cases of Undiagnosed, Clinically Significant COPD in Primary Care: Qualitative Insight from Patients in the Target Population, Nancy K. Leidy, Katherine Kim, Elizabeth D. Bacci, Barbara P. Yawn, David M. Mannino, Byron M. Thomashow, R. Graham Barr, Stephen I. Rennard, Julia F. Houfek, Meilan K. Han, Catherine A. Meldrum, Barry J. Make, Russ P. Bowler, Anna W. Steenrod, Lindsey T. Murray, John W. Walsh, Fernando Martinez, and High-Risk-COPD Screening Study Group
CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice., Casey W. McKenzie, Branch Craige, Tiffany V. Kroeger, Rozzy Finn, Todd A. Wyatt, Joseph H. Sisson, Jacqueline A. Pavlik, University of Massachusetts Medical School, Gregory M. Hendricks, George B. Witman, and Lance Lee
Identifying a Gene Expression Signature of Frequent COPD Exacerbations in Peripheral Blood Using Network Methods, Jarrett D. Morrow, Weiliang Qiu, Divya Chhabra, Stephen I. Rennard, Paula Belloni, Anton Belousov, Sreekumar G. Pillai, and Craig P. Hersh
The Effect of Statins on Blood Gene Expression in COPD, Ma'en Obeidat, Nick Fishbane, Yunlong Nie, Virginia Chen, Zsuzsanna Hollander, ScottJ Tebbutt, Yohan Bossé, Raymond T. Ng, Bruce E. Miller, Bruce McManus, Stephen I. Rennard, Peter D. Paré, and Don D. Sin
MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment., Jill A. Poole, Todd A. Wyatt, Debra J. Romberger, Elizabeth Staab, Samantha Simet, Stephen J. Reynolds, Joseph H. Sisson, and Tammy Kielian
Exercise Improves Host Response to Influenza Viral Infection in Obese and Non-Obese Mice through Different Mechanisms., Kristi J. Warren, Molly M. Olson, Nicholas J. Thompson, Mackenzie L. Cahill, Todd A. Wyatt, Kyoungjin J. Yoon, Christina M. Loiacono, and Marian L. Kohut
Gait mechanics in patients with chronic obstructive pulmonary disease., Jennifer M. Yentes, Kendra Schmid, Daniel Blanke, Debra J. Romberger, Stephen I. Rennard, and Nicholas Stergiou
Submissions from 2014
The Association of Plasma Biomarkers with Computed Tomography-Assessed Emphysema Phenotypes, Brendan J. Carolan, Grant Hughes, Jarrett Morrow, Craig P. Hersh, Wanda K. O'Neal, Stephen I. Rennard, Sreekumar G. Pillai, Paula Belloni, Debra A. Cockayne, Alejandro P. Comellas, Meilan Han, Rachel L. Zemans, Katerina Kechris, and Russell P. Bowler
Analyzing Networks of Phenotypes in Complex Diseases: Methodology and Applications in COPD, Jen-hwa Chu, Craig P. Hersh, Peter J. Castaldi, Michael H. Cho, Benjamin A. Raby, Nan Laird, Russell Bowler, Stephen I. Rennard, Joseph Loscalzo, John Quackenbush, and Edwin K. Silverman
Efficacy and Safety of Fixed-Dose Combinations of Aclidinium Bromide/Formoterol Fumarate: The 24-Week, Randomized, Placebo-Controlled AUGMENT COPD Study, Anthony D. D'Urzo, Stephen I. Rennard, Edward M. Kerwin, Victor Mergel, Anne R. Leselbaum, Cynthia F. Caracta, and AUGMENT COPD study investigators
Sexually-Dimorphic Targeting of Functionally-Related Genes in COPD, Kimberly Glass, John Quackenbush, Edwin K. Silverman, Bartolome Celli, Stephen I. Rennard, Guo-Cheng Yuan, and Dawn L. DeMeo
Influence of Diet and Obesity on COPD Development and Outcomes, Corrine K. Hanson, Erica P. Rutten, Emiel F.M. Wouters, and Stephen I. Rennard
Non-Emphysematous Chronic Obstructive Pulmonary Disease is Associated with Diabetes Mellitus, Craig P. Hersh, Barry J. Make, David A. Lynch, R. Graham Barr, Russell P. Bowler, Peter M.A. Calverley, Peter J. Castaldi, Michael H. Cho, Harvey O. Coxson, Dawn L. DeMeo, Marilyn G. Foreman, MeiLan K. Han, Benjamin J. Harshfield, John E. Hokanson, Sharon Lutz, Joe W. Ramsdell, Elizabeth A. Regan, Stephen I. Rennard, Joyce D. Schroeder, Frank C. Sciurba, Robert M. Steiner, Ruth Tal-Singer, Edwin van Beek, Edwin K. Silverman, James D. Crapo, and COPDGene and ECLIPSE Investigators
Clinical and Computed Tomographic Predictors of Chronic Bronchitis in COPD: A Cross Sectional Analysis of the COPDGene Study, Victor Kim, Adam Davey, Alejandro P. Comellas, Meilan K. Han, George Washko, Carlos H. Martinez, David Lynch, Jin Hwa Lee, Edwin K. Silverman, James D. Crapo, Barry J. Make, Gerard J. Criner, and The COPDGene® Investigators
DNAH5 is Associated with Total Lung Capacity in Chronic Obstructive Pulmonary Disease, Jin Hwa Lee, Merry-Lynn N McDonald, Michael H. Cho, Emily S. Wan, Peter J. Castaldi, Gary M. Hunninghake, Nathaniel Marchetti, David A. Lynch, James D. Crapo, David A. Lomas, Harvey O. Coxson, Per S. Bakke, Edwin K. Silverman, Craig P. Hersh, and the COPDGene and ECLIPSE Investigators
A diVIsive Shuffling Approach (VIStA) for Gene Expression Analysis to Identify Subtypes in Chronic Obstructive Pulmonary Disease, Jörg Menche, Amitabh Sharma, Michael H. Cho, Ruth J. Mayer, Stephen I. Rennard, Bartolome Celli, Bruce E. Miller, Nick Locantore, Ruth Tal-Singer, Soumitra Ghosh, Chris Larminie, Glyn Bradley, John H. Riley, Alvar Agusti, Edwin K. Silverman, and Albert-László Barabási
The omega-3 fatty acid docosahexaenoic acid attenuates organic dust-induced airway inflammation., Tara M. Nordgren, Taylor D. Friemel, Art J. Heires, Jill A. Poole, Todd A. Wyatt, and Debra J. Romberger
Comparison of Serum, EDTA Plasma and P100 Plasma for Luminex-Based Biomarker Multiplex Assays in Patients with Chronic Obstructive Pulmonary Disease in the SPIROMICS Study, Wanda K. O'Neal, Wayne Anderson, Patricia V. Basta, Elizabeth E. Carretta, Claire M. Doerschuk, R. Graham Barr, Eugene R. Bleecker, Stephanie A. Christenson, Jeffrey L. Curtis, Meilan K. Han, Nadia N. Hansel, Richard E. Kanner, Eric C. Kleerup, Fernando J. Martinez, Bruce E. Miller, Stephen P. Peters, Stephen I. Rennard, Mary Beth Scholand, Ruth Tal-Singer, Prescott G. Woodruff, David J. Couper, Sonia M. Davis, and SPIROMICS Investigators
A Simplified Score to Quantify Comorbidity in COPD, Nirupama Putcha, Milo A. Puhan, M. Bradley Drummond, MeiLan K. Han, Elizabeth A. Regan, Nicola A. Hanania, Carlos H. Martinez, Marilyn Foreman, Surya P. Bhatt, Barry Make, Joe Ramsdell, Dawn L. DeMeo, R. Graham Barr, Stephen I. Rennard, Fernando Martinez, Edwin K. Silverman, James Crapo, Robert A. Wise, and Nadia N. Hansel
Randomized Study of the Safety, Pharmacokinetics, and Bronchodilatory Efficacy of a Proprietary Glycopyrronium Metered-Dose Inhaler in Study Patients with Chronic Obstructive Pulmonary Disease, Stephen I. Rennard, Charles Fogarty, Colin Reisner, Carlos Fernandez, Tracy Fischer, Michael Golden, Earl St Rose, Patrick Darken, Gregory Tardie, and Chadwick Orevillo
Roflumilast and Dyspnea in Patients with Moderate to Very Severe Chronic Obstructive Pulmonary Disease: A Pooled Analysis of Four Clinical Trials, Stephen I. Rennard, Shawn X. Sun, Stavros Tourkodimitris, Paul Rowe, Udo M. Goehring, Dirk Bredenbröker, and Peter M.A. Calverley
Submissions from 2013
PGE 2 Desensitizes β -Agonist Effect on Human Lung Fibroblast-Mediated Collagen Gel Contraction Through Opregulating PDE4, Qiuhong Fang, Yingmin Ma, Jing Wang, Joel Michalski, Stephen I. Rennard, and Xiangde Liu
Effect of Budesonide on Fibroblast-Mediated Collagen Gel Contraction and Degradation, Qiuhong Fang, Nancy A. Schulte, Huijung Kim, Tetsu Kobayashi, Xingqi Wang, Anna Miller-Larsson, Elisabet Wieslander, Myron L. Toews, Xiangde Liu, and Stephen I. Rennard
Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust., Tara M. Nordgren, Art J. Heires, Todd A. Wyatt, Jill A. Poole, Tricia D. LeVan, D. Roselyn Cerutis, and Debra J. Romberger
Vest Chest Physiotherapy Airway Clearance is Associated with Nitric Oxide Metabolism., Joseph H. Sisson, Todd A. Wyatt, Jacqueline A. Pavlik, Pawanjit S. Sarna, and Peter J. Murphy
Anti-Inflammatory Effects of Budesonide in Human Lung Fibroblast are Independent of Histone Deacetylase 2, Xingqi Wang, Amy J. Nelson, Zachary M. Weiler, Amol Patil, Tadashi Sato, Nobuhiro Kanaji, Masanori Nakanishi, Joel Michalski, Maha Farid, Hesham Basma, Tricia D. Levan, Anna Miller-Larsson, Elisabet Wieslander, Kai-Christian Muller, Olaf Holz, Helgo Magnussen, Klaus F. Rabe, Xiangde Liu, and Stephen I. Rennard
Asymmetric dimethylarginine blocks nitric oxide-mediated alcohol-stimulated cilia beating., Todd A. Wyatt, S . M. Wells, Z . A. Alsaidi, Jane M. DeVasure, E. B. Klein, Kristina L. Bailey, and Joseph H. Sisson
Submissions from 2012
Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype, Alvar Agustí, Lisa D. Edwards, Stephen I. Rennard, William MacNee, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, David A. Lomas, Peter M.A. Calverley, Emiel Wouters, Courtney Crim, Julie C. Yates, Edwin K. Silverman, Harvey O. Coxson, Per Bakke, Ruth J. Mayer, Bartolome Celli, and Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
Examining Fatigue in COPD: Development, Validity and Reliability of a Modified Version of FACIT-F Scale, Khaled Al-shair, Hana Muellerova, Janelle Yorke, Stephen I. Rennard, Emiel F.M. Wouters, Nicola A. Hanania, Amir Sharafkhaneh, Jørgen Vestbo, and ECLIPSE investigators
Non-typeable Haemophilus influenzae decreases cilia beating via protein kinase Cε., Kristina L. Bailey, Tricia D. LeVan, Daniel A. Yanov, Jacqueline A. Pavlik, Jane M. DeVasure, Joseph H. Sisson, and Todd A. Wyatt
Effects of Inhaled Corticosteroids on Airway Inflammation in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis, Rachel Jen, Stephen I. Rennard, and Don D. Sin
Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency., Woo Jin Kim, Alice M. Wood, Alan F. Barker, Mark L. Brantly, Edward J. Campbell, Edward Eden, Gerard McElvaney, Stephen I. Rennard, Robert A. Sandhaus, James M. Stocks, James K. Stoller, Charlie Strange, Gerard Turino, Edwin K. Silverman, Robert A. Stockley, and Dawn L. Demeo
Alcohol exposure alters mouse lung inflammation in response to inhaled dust., Michael L. McCaskill, Debra J. Romberger, Jane M. DeVasure, Jessica Boten, Joseph H. Sisson, Kristina L. Bailey, Jill A. Poole, and Todd A. Wyatt
A Randomized Placebo-Controlled Trial of Varenicline for Smoking Cessation Allowing Flexible Quit Dates, Stephen I. Rennard, John Hughes, Paul M. Cinciripini, Eva Kralikova, Tobias Raupach, Carmen Arteaga, Lisa B. St Aubin, Cristina Russ, and the Flexible Quit Date Study Group
Submissions from 2011
Efficacy and Safety of Once-Daily Aclidinium in Chronic Obstructive Pulmonary Disease, Paul W. Jones, Stephen I. Rennard, Alvar Agusti, Pascal Chanez, Helgo Magnussen, Leonardo Fabbri, James F. Donohue, Eric D. Bateman, Nicholas J. Gross, Rosa Lamarca, Cynthia Caracta, and Esther Garcia Gil
Genetics of Sputum Gene Expression in Chronic Obstructive Pulmonary Disease, Weiliang Qiu, Michael H. Cho, John H. Riley, Wayne H. Anderson, Dave Singh, Per Bakke, Amund Gulsvik, Augusto A. Litonjua, David A. Lomas, James D. Crapo, Terri H. Beaty, Bartolome R. Celli, Stephen I. Rennard, Ruth Tal-Singer, Steven M. Fox, Edwin K. Silverman, Craig P. Hersh, and ECLIPSE Investigators
Reduction of Exacerbations by the PDE4 inhibitor roflumilast--the Importance of Defining Different Subsets of Patients with COPD, Stephen I. Rennard, Peter M.A. Calverley, Udo M. Goehring, Dirk Bredenbröker, and Fernando J. Martinez
Differentiation of Embryonic Stem Cells into Fibroblast-Like Cells in Three-Dimensional Type I Collagen Gel Cultures, Shinsaku Togo, Tadashi Sato, Hisatoshi Sugiura, Xingqi Wang, Hesham Basma, Amy J. Nelson, Xiangde Liu, Tom W. Bargar, J. Graham Sharp, and Stephen I. Rennard
Submissions from 2010
Characterisation of COPD Heterogeneity in the ECLIPSE Cohort, Alvar Agusti, Peter M.A. Calverley, Bartolome Celli, Harvey O. Coxson, Lisa D. Edwards, David A. Lomas, William MacNee, Bruce E. Miller, Steve I. Rennard, Edwin K. Silverman, Ruth Tal-Singer, Emiel Wouters, Julie C. Yates, Jørgen Vestbo, and the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators
Sputum Neutrophils as a Biomarker in COPD: Findings From the ECLIPSE Study, Dave Singh, Lisa Edwards, Ruth Tal-Singer, and Stephen I. Rennard
Submissions from 2009
A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci, Sreekumar G. Pillai, Dongliang Ge, Guohua Zhu, Xiangyang Kong, Kevin V. Shianna, Anna C. Need, Sheng Feng, Craig P. Hersh, Per Bakke, Amund Gulsvik, Andreas Ruppert, Karin C. Lødrup Carlsen, Allen Roses, Wayne Anderson, Stephen I. Rennard, David A. Lomas, Edwin K. Silverman, David B. Goldstein, and ICGN Investigators
Submissions from 2008
One-Year Treatment with Mometasone Furoate in Chronic Obstructive Pulmonary Disease, Peter M.A. Calverley, Stephen I. Rennard, Harold S. Nelson, Jill P. Karpel, Eduardo H. Abbate, Paul Stryszak, and Heribert Staudinger
NF-kappaB Mediates the Survival of Human Bronchial Epithelial Cells Exposed to Cigarette Smoke Extract, Xiangde Liu, Shinsaku Togo, Mona Al-Mugotir, Huijung Kim, Qiuhong Fang, Tetsu Kobayashi, Xingqi Wang, Lijun Mao, Peter Bitterman, and Stephen I. Rennard
Submissions from 2005
TGF-beta1 and Serum Both Stimulate Contraction but Differentially Affect Apoptosis in 3D Collagen Gels, Tetsu Kobayashi, Xiangde Liu, Hui Jung Kim, Tadashi Kohyama, Fu-Qiang Wen, Shinji Abe, Qiuhong Fang, Yun Kui Zhu, John R. Spurzem, Peter Bitterman, and Stephen I. Rennard
Submissions from 2003
Platelets Stimulate Fibroblast-Mediated Contraction of Collagen Gels, Ulrika Zagai, Karin Fredriksson, Stephen I. Rennard, Joachim Lundahl, and C. Magnus Sköld
Submissions from 1998
Repair of the Airway Epithelium: Potential Opportunities for Therapeutic Intervention in Airway Disease, Stephen I. Rennard
Submissions from 1996
Efficient Vasoactive Intestinal Polypeptide Hydrolyzing Autoantibody Light Chains Selected by Phage Display, Sonia Tyutyulkova, Qing-Sheng Gao, Austin Thompson, Stephen I. Rennard, and Sudhir Paul