Document Type

Capstone Experience

Graduation Date

8-2025

Degree Name

Master of Public Health

Department

Epidemiology

First Committee Member

Dr. Brittney Dickey

Second Committee Member

Dr. Nicole Kolm-Valdivia

Third Committee Member

Dr. Julie Petersen

Fourth Committee Member

Dr. Marouf Balde

Abstract

Background: Viral suppression among children living with HIV (CLHIV) remains suboptimal in Côte d’Ivoire. This study assessed clinical, socioeconomic, and demographic characteristics associated with viral non-suppression among CLHIV aged 2–14 years in Abidjan 2 to inform targeted interventions under the U.S. Agency for International Development (USAID)-supported Reaching Impact, Saturation, and Epidemic Control (RISE) project.

Methods: A retrospective analysis was conducted using routine program data from 1,203 CLHIV across 73 health facilities. Descriptive, bivariate, and multivariate analyses were performed to examine associations with viral load suppression status. Findings guided the development of a multi-level implementation plan using Kotter’s Change Management Framework, the Socio-Ecological Model, and Transformational Leadership Theory.

Results: Of 1,203 CLHIV, 513 had documented VL results, and 14.4% were non-suppressed. Missingness was substantial for key variables, including HIV disclosure (71%) and parental HIV status (74%). In multivariate modeling, older age (10–14 years) was significantly associated with non-suppression (adjusted prevalence ratio = 2.47; 95% CI, 1.05–5.82). Other factors, including parental HIV status, ART regimen, pill burden, and Orphans and Vulnerable Children program enrollment, were not statistically significant but revealed data quality and structural service gaps.

Conclusion: Pediatric VL suppression in Abidjan 2 is compromised by both clinical and structural barriers. Strategies should focus on improving documentation, supporting age-appropriate disclosure, and implementing tailored adherence interventions. Recommendations are based on both literature and direct program experience, with future research needed to address unmeasured factors such as caregiver occupation, income level, and distance to health facilities.

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