Theses/Dissertations from 2023
Phenotypic and Target-based Drug Discovery, Angelica Veronica Carmona
Creation of TatDE rLNPs for the Excision of Integrated HIV-1 Proviral DNA, Mahmudul Hasan
Targeting Metabolic Switches and DNA Damage Repair for the Treatment of Human Diseases, Rasangi Chathurika Kankanam Pathirage
Paper-based Ratiometric Sensor Array for Pathogenic Bacterial Species Identification, Aayushi Laliwala
Design, Synthesis, and Evaluation of Novel Peptidomimetics as Neurolysin Activators for the Treatment of Ischemic Stroke., Md. Shafikur Rahman
Targeted Therapies for Improving the Treatment of Sonic Hedgehog and MYC Driven Medulloblastoma, Bharti Sethi
Design and Synthesis of Small Molecule Drugs for CNS Disorders, Kirsten T. Tolentino
Dynamics of Site Search Process and Formation of Synaptosome Assembly Characterized by Single Molecule Approaches, Sridhar Vemulapalli
Design, Synthesis, and Characterization of Peptide Amphiphile Biomaterials, Huihua Xing
Polycationic Nanoparticle Delivery of Nucleic Acids for the Treatment of Fibrosis in Alcohol-Associated Liver Diseases, Chuhan Zhang
Theses/Dissertations from 2022
Biologically-Inspired Nanoparticles For Oncology Applications, Aishwarya Bapat
Targeted Therpeutics for Prostate Cancer, Behind the Scenes of PSMA & Cysteine Protease Trapping Mechanism, Alireza Basiri
Polymeric Nanocarriers for Delivery of Small Molecules Inhibiting Tubulin Polymerization for the Treatment of Pancreatic Cancer and Lung Metastatic Melanoma, Rajan Sharma Bhattarai
The Development of Thermoresponsive Hydrogel-Based Drug Delivery Systems for the Treatment of Musculoskeletal Diseases, Ningrong Chen
Development of Perfluorocarbon Nanoemulsions for Delivery of Therapeutic Nucleic Acids, Ling Ding
Structural and Biochemical Studies of Three Enzymes Involved in Amino Acid Metabolism to Develop Novel Drugs, Yahani Pankaja Jayasinghe Arachchige
Structural and Inhibitory Studies on (i)Two Mycobacterium Tuberculosis Enzymes Essential for Capsular Glucan Biosynthesis and mRNA Degradation: (Ii) Hantann Virus L-Protein Endonuclease Domain, Hettiarachchige Thilina D. Jayasinghe
Macromolecular Fluorescent Conjugates for Bioimaging Applications, Paul Lovell
Innate Immunity in the Pathobiology and Treatment of Infectious and Neurodegenerative Diseases, Mai Mostafa
The Development and In Vivo Immunologic Assessment of Biodegradable Microparticles Incorporating CPDI-02 and Mucosal Protein Vaccine, Jacob E. Parriott
Applications of Population Pharmacokinetic Modeling in People Living with HIV, Michelle M. Pham
Design, Synthesis, and Biological Investigation of Pyridine Sulfones as Anti-Chlamydia trachomatis Agents, Mohamed A. Seleem
Dynamics of Nucleosome Assembly Characterized by Atomic Force Microscopy, Tommy Stormberg
Development of Bioactive Polymers for Anticancer siRNA Therapy, Siyuan Tang
Modulation of Immune Homeostasis in Neurodegenerative Diseases, Pravin Yeapuri
Nanofabrication for Precision Vaccinology, Karen Zagorski
The Development of Polymeric Dexamethasone Prodrug Nanomedicines for the Treatment of Lupus Nephritis, Zhifeng Zhao
Theses/Dissertations from 2021
Modification and Antichlamydial Activity Evaluation on Dysregulators of Cylindrical Proteases, Jiachen Feng
Design, Synthesis and Antineoplastic Evaluation of a Variety of Small Molecule Scaffolds, Bader Huwaimel
Development of Once-A-Year Injectable Formulation of Cabotegravir for Prevention and Treatment of HIV Infection, Tanmay Abhay Kulkarni
Urinary Bile Acid Indices as Prognostic Biomarkers for the Complications of Liver Diseases, Wenkuan Li
Design, Synthesis and Evaluation of Novel Inhibitors of Type 5 and 10 17β-Hydroxysteroid Dehydrogenases, Ahmed Morsy
Development of Macromolecular Prodrug of Sinomenine for the Treatment of Rheumatoid Arthritis, Roshni Mukundan
Design and Synthesis of Small Molecular probes for CNS and Kidney Disorders, Swagat H. Sharma
Structural and Inhibitory Studies of Enzymes Essential for Cell Wall and Ergothioniene Biosynthesis in Mycobacterium Tuberculosis, Thanuja D. Sudasinghe
Development of Polymeric CXCR4 Targeting Carriers for siRNA Delivery to Treat Acute Kidney Injury, Weimin Tang
Dynamics of Protein-DNA Interactions Characterized by Atomic Force Microscopy, Yaqing Wang
Delivery of SiRNA with Drugs Targeting Polyamine Metabolism as Combinational Cancer Treatment, Ao Yu
Theses/Dissertations from 2020
Urinary Bile Acid Indices as Diagnostic and Prognosic Biomarkers for Liver Diseases, Jawaher Alamoudi
Development of an LC-ESI-MS/MS method for determination of a novel Pyrrolomycin (MP-1) and application to pre-clinical ADME studies, Wafaa N. Aldhafiri
Delivery for Hydrophobic Drugs for Treating Pancreatic Cancer, Saud Almawash
Polymeric Drug Delivery Systems for Cancer Therapy and Radionuclide Decorporation, Sameer A. Alshehri
Ocular, Neural, and Cellular Biodistribution of Multifunctional Antioxidants, Damian Daszynski
Next Generation Aryl Hydantoins as Antischistosomal Agents, Derek A. Leas
Smart Delivery of Genes and Drugs for Treatment of Cancer, Feng Lin
Rilpivirine-Associated Aggregation-Induced Emission Enables Cell-Based Nanoparticle Tracking, Insiya Mukadam
Anti-MUC4β antibodies as a novel therapeutic modality for the treatment of pancreatic cancer, Catherine Orzechowski
Development of Hyaluronic Acid-Derived Macromolecular Agents for Multimodal Imaging Probes and Nanomedicine, William M. Payne
Long-Acting Nanoformulated Antivirals for the Treatment and Prevention of HIV-1 and HBV infections, Dhruvkumar M. Soni Dr.
Ligand-Installed Polymeric Nanocarriers for Combination Chemotherapy, Xinyuan Xi
Development of Cholesterol Modified RNAi Polyplexes for Breast Cancer Therapy, Zhen Ye
Theses/Dissertations from 2019
Computational Studies and Design of PPARγ and GLUT1 Inhibitors, Suliman Almahmoud
Development of Local Drug Delivery Systems for Periodontal Disease, Yosif Hassan Almoshari
Identification of more potent and efficacious analogs of the novel host-derived immunostimulant EP67, Abdul Alshammari
Engineering Hyaluronic Acid for Biomedical Applications, Deep S. Bhattacharya
Development of Long-acting Nanoformulated Abacavir ProTides, Zhiyi Lin and Howard E. Gendelmant
Polymeric Chloroquine: Modifying an Old Drug to Make It a Little Sweeter, Richard Sleightholm
Macromolecular Prodrug for the Treatment of Ulcerative Colitis, Yuanyuan Sun
Development of Approaches of Tumor Trapping Enhanced BB2R-Targeted Radiopharmaceuticals for Prostate Cancer, Wenting Zhang
Development of Macromolecular Prodrug Conjugates for the Treatment of Inflammatory Diseases, Gang Zhao
Theses/Dissertations from 2018
Development of Polymeric Carriers for the Treatment of Acute Kidney Injury, Yi Chen
Molecular Mechanism of Early Amyloid Self-Assembly Revealed by Computational Modeling, Mohtadin Hashemi
Development of Novel Therapies for the Treatment of Inflammatory Bowel Disease, Shrey Kanvinde
Developing of Micellar Drug Carriers for the Treatment of Breast Cancer Bone Metastasis, Tong Liu
The Opposing Roles of GluN2C and GluN2D NMDA Receptor Subunits in Modulating Neuronal Oscillations, Zhihao Mao
Development of Glucocorticoid Prodrug for the Treatment of Lupus Nephritis, Xiaobei Wang
Development of Macromolecular Prodrugs for the Treatment of Chronic Inflammatory Pain, Laura Weber
Delivery of MicroRNA with CXCR4-Targeted Nanoparticles in Metastatic Cancer Treatment, Ying Xie
Development of Chloroquine-containing HPMA Copolymers for Drug Delivery, Fei Yu
Next Generation of Translational Long-Acting Cabotegravir, Tian Zhou
Theses/Dissertations from 2017
Development of CXCR4 Inhibitors for Topical Treatment of Psoriasis, Suthida Boonsith
Development of Neurotensin-Based Radiopharmaceuticals For Neurotensin-Receptor-1-Positive Tumors Targeting, Yinnong Jia
Targeted Delivery of Drug Combinations Via Nanocarriers for Cancer Treatment, Kruti Soni
Development of C5AR-Targeted Nanoparticles for Delivery of Vaccines, Shailendra Bharadwaj Tallapaka Venkata Sesha
In-Vitro and In-Vivo Models of Bile Acid Metabolism and Transport, Rhishikesh Thakare
Delivery of small molecule and RNA for the treatment of type 1 diabetes and prostate cancer, Di Wen
Theses/Dissertations from 2016
Long-Acting Antiretroviral Nanoformulation Development and Subcellular Trafficking, Dongwei Guo
Chemosensitization Effect of SP1017 on Multiple Myeloma, Hangting Hu
Polymeric Nanocarriers for Delivery of Small Molecules and miRNAs for the Treatment of Liver Fibrosis and Pancreatic Cancer, Virender Kumar
Synthesis and Development of Long-Acting Abacavir Prodrug Nanoformulations, Dhirender Singh
Stability and Kinetics of DNA Pseudoknots: Formation of T∗A•T Base-Triplets and Their Targeting Reactions, Calliste Steffensmeier
Block Copolymer Based Magnetic Nanoclusters for Cancer-Theranostics: Synthesis, Characterization and In Vitro Evaluation, Hemant M. Vishwasrao
Design, Synthesis, and Evaluation of Aryl Hydantoins and Ureas as Antischistosomal Agents, Chunkai Wang
Development of CXCR4-Inhibiting Nanoparticles for the Treatment of Metastatic Cancer, Yan Wang
The Functions of the CID and lRG Operons in S. Aureus Programmed Cell Death, Xinyan Zhang
Theses/Dissertations from 2015
Biodegradable Hybrid Nanogels for Combination Chemotherapy, Swapnil Desale
Polymeric Nanocarriers for Treatment of Melanoma and Genetically Modified Mesenchymal Stem Cells to Improve Outcome of Islet Transplantation, Vaibhav Mundra
Development of Polymer Peptide Conjugates for Enhanced Pancreatic Cancer Imaging, Wen Shi
Effect of peripheral shell cross-linking on the efficacy of a hydrophobic vascular disrupting agent physically loaded in core-shell polymeric micelles, Rajesh Rajan Wakaskar
Antiviral Peptide Nanocomplexes As Potential Therapeutics For The Treatment Of Infectious Diseases, Jinjin Zhang
The targeted delivery of bone anabolic agents to improve fracture healing, Yijia Zhang
Amyloid Proteins Structure, Dynamics, Interactions and Early Stages of Self-Assembly, Yuliang Zhang
Development of Hypoxia Trapping Enhanced BB2R-Targeted Radiopharmaceutics for Prostate Cancer, Zhengyuan Zhou