Theses/Dissertations from 2015
The targeted delivery of bone anabolic agents to improve fracture healing, Yijia Zhang
Amyloid Proteins Structure, Dynamics, Interactions and Early Stages of Self-Assembly, Yuliang Zhang
Development of Hypoxia Trapping Enhanced BB2R-Targeted Radiopharmaceutics for Prostate Cancer, Zhengyuan Zhou
Theses/Dissertations from 2014
Development of EP67-based mucosal vaccines against cytomegalovirus infection, Bala Vamsi Krishna Karuturi
Misfolding and aggregation of yeast prion protein SUP35P using atomic force microscopy and complementary biophysical methods, Alexander M. Portillo
Remote actuation of magnetic nanoparticles in breast cancer cells, Philise Nicole Williams
Development of macromolecular prodrugs for improved treatment of lupus nephritis, Fang Yuan
The structure and function of caveolin proteins, Yanli Zhang
Theses/Dissertations from 2013
Cholesterol-siRNA polyplexes of polycation-polyethylene glycol diblock copolymers for cancer therapy, Vishakha Vilas Ambardekar
Bile acids as biomarkers for hepatobiliary diseases, Sai Praneeth Reddy Bathena
Multi-functional antioxidants targeting neurodegenerative diseases, Hiroyoshi Kawada
Development of a theranostic system for aseptic implant loosening, Ke Ren
Theses/Dissertations from 2012
Mechanistic study of pluronic interactions in multidrug resistant and tumor initiating cells, Daria Y. Alakhova
Population pharmacokinetic analysis of anti-retroviral therapies, Gautam Baheti
Dentotropic technologies for the prevention and treatment of dental plaque related diseases, Fu Chen
Computational studies and inhibitors design of P13Kalpha, Dima Sabbah
Theses/Dissertations from 2011
AFM characterization of protein-DNA interactions, Jamie Gilmore
Polymer micelles with cross-linked ionic cores for delivery of platinum anticancer agents, Hardeep Singh Oberoi
Development of multi-functional antioxidants for use in cataract and age-related macular degeneration, James Michael Randazzo
Retinal delivery of steroidal and non-steroidal drugs for the treatment of back of the eye disorders, Ashish Thakur
Theses/Dissertations from 2010
Bis-styrylbenzenes and their potential in alzheimer's disease, Daniel P. Flaherty
Design and synthesis of a click polyrotaxane for the improved treatment of musculoskeletal diseases, Christopher Donald Hein
Polymer micelles with cross-linked ionic cores for delivery of doxorubicin, Jung Oh Kim
Protein modification by pluronic block copolymer for brain delivery, Xiang Yi
Theses/Dissertations from 2009
Pluronic block copolymers for non-viral gene therapy, Zagit Z. Gaymalov
Atomic force microscopy characterization of misfolding and aggregation of yeast prion protein SUP35P, Alexander M. Portillo
Tat-conjugated nanoparticles for the cns delivery of anti-hiv drugs, Kavitha S. Rao
Mechanism (s) of encocytosis for cellular entry of novel nanomaterials, Gaurav Sahay
The interaction of DNA polymerases with N3-Methyladenine and related analogs, Sam Settles
Targeted drug delivery for the management of choroidal neovascularization, Swita R. Singh
Deslorelin functionalized nanosystems for anti-cancer drug and gene delivery, Sneha Sundaram
Theses/Dissertations from 2008
Effect of size of PLGA and chitosan-PLGA particles on the cellular association, cytotoxicity, and anti-tumor efficacy of Paclitaxel, Sudhir S. Chakravarthi
Transscleral drug delivery : role of physiological, physico-chemical and pathological factors in delivering drugs to the posterior segment of eye, Narayan PS Cheruvu
Thermodynamic characterization of the folding and interactions of G-Quadruplexes, Christopher Michael Olsen
Nanoparticle-cell interactions, intracellular trafficking, and protein therapy for restenosis, Jaspreet K. Vasir
Theses/Dissertations from 2007
Periocular particulate systems: disposition, safety and efficacy, Aniruddha C. Amrite
Pharmacokinetic modeling of therapeutic antibodies, Jasmine P. Davda
Biophysical characterization of DNA duplexes containing modified nucleotides that influence DNA hydration and cation organization, Manjori Ganguly
Supercritical fluid technology for fabrication of gene delivery nanoparticles, Aaron S. Mayo
Effects of pluronic block copolymers on gene delivery and expression, Srikanth Sriadibhatla
Theses/Dissertations from 2006
Cross Linked Polymer Micelles for Cisplatin Delivery, Satya S. Bontha
Physiological and pathophysiological modulation of blood-brain barrier integrity, Sanjot D. Savant
Theses/Dissertations from 2005
Physiologically based pharmacotkinetic (PBPK) modeling of anticancer drugs, Jing Li
Energetics, ion and water binding in the unfolding of DNA : nearest neighbor contributions and incorporation of bulges, mismatches, cationic chains and base-triplet stacks, Ronald Angel Shikiya
Study of self-assembly and environmental response properties of block ionomer complexes, Sergey V. Solomatin
Tumor necrosis factor alpha (TNF) induced alterations in brain microvessel endothelial cell (BMEC) permeability, William J. Trickler
Theses/Dissertations from 2004
Retinal delivery of drugs capable of inhibiting VEGF expression, Surya P. Ayalasomayajula
Functional assays for drug efflux transporters in the blood-brain barrier, Corbin J. Bachmeier
Respiratory delivery of deslorelin, a peptide drug, Kavitha Koushik
Mechanism and efficacy of nanoparticle-mediated WT-P53 gene therapy in breast cancer model, Swayam Prabha
Theses/Dissertations from 2003
Lung delivery of budesonide and its efficacy in a tumour model, Nagesh Bandi
Biodegradable nanoparticles : formulation, cellular mechanism and application for restenosis, Jayanth Panyam
Innovative approaches to pharmacokinetic model selection, Steven P. Riley
Sequence specific DNA minor groove alkylating agents and their biological activity, Dharini Shah
Theses/Dissertations from 2002
Retinal delivery of an aldose reductase inhibitor and a VEGF antisense oligonucleotide, Jithan V. Aukunuru
The In vitro and in vivo transport of the novel lipophilic, silicon-containing, camptothecin, DB-67, Christine M. Brandquist
Studies of alginate particulate formulations prepared by ionotropic gelation containing small molecules or deslorelin, Preeti Dochibhotla
Block ionomer complexes with retinoic acid for drug delivery, Andrew John Nehls
Thermodynamics for the unfolding of non-canonical nucleic acids : bent duplexes, okazaki fragments and DNA triplexes, Ana Maria Soto
Transport, pharmacokinetics and ocular delivery of N-4-[(Benzoylamino)phenylsulfonyl]glycine : an aldose reductase inhibitor, Gangadhar Sunkara
Theses/Dissertations from 2001
Oxidation of 4-hydroxycatechol estrogens to their genotoxic quinones by transition metal ions, cytochrome P450 with linoleic acid hydroperoxide as cofactor, and prostaglandin H synthase-1, Lisa Zaddock Crandall
Estimation of population pharmacokinetic parameters in the presence of noncompliance, Song Mu
Organic anion transport in the central nervous system : a study of fluorescein cns distributional kinetics, Haiying Sun
Theses/Dissertations from 2000
Synthesis and characterization of chemically modified oligonucleotides and sequence specific DNA alkylating agents, Prasad Dande
Nanospheres for the sustained delivery of vascular endothelial growth factor in angiogenesis therapy, Jasmine P. Davda
The Design and development of a biodegradable polylactide reservoir for controlled, zero-order drug delivery, Sriramakamal Jonnalagadda
Allyl sulfide inhibition of the metabolism of methylamylnitrosamine, Chantey R. Morris
Theses/Dissertations from 1999
Regulation of phosphatase activity of calcineurin, Bo Feng
Characterization of tumor necrosis factor-alpha (TNF-alpha) induced permeability effects in brain microvessel endothelial cells, Karen S. Mark
Examination of BCECF-AM as a probe for druge efflux transporters, Aimee Beth Schreiner
Role of albumin in tolbutamide metabolism by liver microsomes, Bing Wang
Theses/Dissertations from 1998
Aromatic hydrocarbon radical cations and their reactions with nucleosides and DNA. Metabolic activation of 6-methylbenzo[a]pyrene, Aaron A. Hanson
Modified thymines used in potential antisense therapies, Lauren E. Heystek
In vitro and in vivo properties of an in situ forming gel for the parenteral delivery of macromolecular drugs, Rajashree Joshi
An in situ-gelling system for the extended delivery of ophthalmic drugs, Shilpa Kaushik
In vitro pharmacokinetics and pharmacodynamics of BCNU, Hiroko Ueda
Chloroquine, hematin and malaria, Sudha Rani Vippagunta
Theses/Dissertations from 1997
Theses/Dissertations from 1996
Feasibility and in vitro characterization of an injectable, in situ gel-forming system for enzyme replacement therapy, Sandeep Kumar
The effects of 5-fluorouracil incorporation on the structure and stability of nucleic acids, Parag V. Sahasrabudhe
Assessment and comparison of the renal disposition of cyclosporine A and cyclosporine G in the isolated perfused rat kidnay, Michelle Lynne Strong
Theses/Dissertations from 1995
The relationship between dimethylnitrosamine metabolism and DNA methylation in isolated rat hepatocytes, Lance Encell
Design and characterization of deferoxamine derivatives with improved biomembrane permeability, Peter M. Ihnat
The use of chemical reagents to sequence DNA and probe DNA structure, Gangning Liang
The effects of 5-fluorouridine incorporation on the structure of the 5'stem-lopf from U4-snRNA, Junqu Sun
Theses/Dissertations from 1994
Development and evaluation of biodegradable films for the controlled release of tetracycline HC1 into intracrevicular fluid, Rajesh Kumar Agarwal
Physicochemical aspects of dissolution and controlled release of mesalamine and structurally related compounds from carbopol gels, Donna L. French
Theses/Dissertations from 1993
Dissolution kinetics of calibrator and matrix tablets in the U.S.P. dissolution apparatus, Kenneth R. Freebern
Biodegradable antibiotic delivery systems for the localized treatment of osteomyelitis, Monica Ramchandani