Submissions from 2024
Metabolism Shapes Immune Responses to Staphylococcus aureus., Prabhakar Arumugam and Tammy Kielian
C1q is Elevated during Chronic Staphylococcus Epidermidis Central Nervous System Catheter Infection, Matthew K. Beaver, Lara Bergdolt, Anna Dunaevsky, Tammy Kielian, and Gwenn Skar
Elucidating Granulocytic Myeloid-Derived Suppressor Cell Heterogeneity During Staphylococcus Aureus Biofilm Infection, Blake P. Bertrand, Cortney E. Heim, Scott A. Koepsell, and Tammy Kielian
Metabolic Diversity of Human Macrophages: Potential Influence on Staphylococcus Aureus Intracellular Survival, Blake P. Bertrand, Dhananjay Shinde, Vinai C. Thomas, Marvin Whiteley, Carolyn B. Ibberson, and Tammy Kielian
Antimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes, Seoung-Ryoung Choi, Mohammed A. Hassan, Bradley E. Britigan, and Prabagaran Narayanasamy
Granulocytic Myeloid-Derived Suppressor Cell Activity During Biofilm Infection is Regulated by a glycolysis/HIF1a Axis, Christopher M. Horn, Prabhakar Arumugam, Zachary Van Roy, Cortney E. Heim, Rachel W. Fallet, Blake P. Bertrand, Dhananjay Shinde, Vinai Chittezham Thomas, Svetlana Romanova, Tatiana K. Bronich, Curtis Hartman, Kevin Garvin, and Tammy Kielian
Bacterial Single-Cell RNA Sequencing Captures Biofilm Transcriptional Heterogeneity and Differential Responses to Immune Pressure, Lee E. Korshoj and Tammy Kielian
Aconitate Decarboxylase 1 Mediates the Acute Airway Inflammatory Response to Environmental Exposures, Aaron Schwab, Amy J. Nelson, Angela Gleason, Oliver Schanze, Todd A. Wyatt, Dhananjay Shinde, Peng Xiao, Vinai Chittezham Thomas, Chittibabu Guda, Kristina L. Bailey, Tammy Kielian, Geoffrey M. Thiele, and Jill A. Poole
Dual Gallium Drug Treatment Against Carbapenem-Resistant Klebsiella Pneumoniae: Efficacy and Potential Mechanism(s) of Action and Resistance, Zachary Scott, Seoung-Ryoung Choi, Bradley E. Britigan, and Prabagaran Narayanasamy
Tetracycline and Oxacillin Act Synergistically on Biofilms and Display Increased Efficacy In Vivo Against Staphylococcus aureus, Amy K. Tooke, Rebecca E. Hodges, Josie F. Pyrah, Kenneth W. Bayles, Stephen A. Renshaw, and Simon J. Foster
Single-Cell Profiling Reveals a Conserved Role for Hypoxia-Inducible Factor Signaling During Human Craniotomy Infection, Zachary Van Roy, Gunjan Kak, Lee E. Korshoj, Joseph P. Menousek, Cortney E. Heim, Rachel W. Fallet, James Campbell, Carol Reynolds Geary, Bo Liu, Santhi Gorantla, Larisa Y Poluektova, Bin Duan, Walter S. Campbell, William Thorell, and Tammy Kielian
Submissions from 2023
Androgen Receptor Inhibition Suppresses Anti-Tumor Neutrophil Response Against Bone Metastatic Prostate Cancer via Regulation of TβRI Expression, Massar Alsamraae, Diane Costanzo-Garvey, Benjamin A. Teply, Shawna Boyle, Gary Sommerville, Zachary T. Herbert, Colm Morrissey, Alicia J. Dafferner, Maher Y. Abdalla, Rachel W. Fallet, Tammy Kielian, Heather Jensen Smith, Edson I. deOliveira, Keqiang Chen, Ian A. Bettencourt, Ji Ming Wang, Daniel W. McVicar, Tyler Keeley, Fang Yu, and Leah M. Cook
Bacteria Commonly Associated with Central Nervous System Catheter Infections Elicit Distinct CSF Proteome Signatures, Matthew K. Beaver, Dragana Noe, Ishwor Thapa, Hesham Ali, Jessica Snowden, Tammy Kielian, and Gwenn Skar
Investigating Novel IspE Inhibitors of the MEP Pathway in Mycobacterium, Seoung Ryoung Choi and Prabagaran Narayanasamy
An Intravenous Pancreatic Cancer Therapeutic: Characterization of CRISPR/Cas9n-Modified Clostridium novyi-Non Toxic, Kaitlin M. Dailey, James M. Small, Jessica E. Pullan, Seth Winfree, Krysten E. Vance, Megan Orr, Sanku Mallik, Kenneth W. Bayles, Michael A. Hollingsworth, and Amanda E Brooks
Advances in Antimicrobial Peptide Discovery via Machine Learning and Delivery via Nanotechnology, Alexa Sowers, Guangshun Wang, Malcolm Xing, and Bingyun Li
The Antimicrobial Peptide Database is 20 Years Old: Recent Developments and Future Directions, Guangshun Wang
Submissions from 2022
Datasets for the Reporting of Primary Tumour in Bone: Recommendations From the International Collaboration on Cancer Reporting (ICCR), Judith V. M. G. Bovée, Fleur Webster, Fernanda Amary, Daniel Baumhoer, J. L. Hans Bloem, Julia A. Bridge, Justin M. M. Cates, Enrique de Alava, Angelo Paolo Dei Tos, Kevin B. Jones, Annabelle Mahar, G. Petur Nielsen, Alberto Righi, Andrew J. Wagner, Akihiko Yoshida, and Christopher D. M. Fletcher
Expanding the Landscape of Amino Acid-Rich Antimicrobial Peptides: Definition, Deployment in Nature, Implications for Peptide Design and Therapeutic Potential, Aaron P. Decker, Abraham F. Mechesso, and Guangshun Wang
The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism, Jennifer L. Endres, Sujata S. Chaudhari, Xinyan Zhang, Janani Prahlad, Shu-Qi Wang, Lily A. Foley, Sorin Luca, Jeffrey L. Bose, Vinai C. Thomas, and Kenneth W. Bayles
IFN-γ Attenuates Eosinophilic Inflammation but Is Not Essential for Protection against RSV-Enhanced Asthmatic Comorbidity in Adult Mice, Abenaya Muralidharan, Md Bashir Uddin, Christopher Bauer, Wenzhe Wu, Xiaoyong Bao, and Keer Sun
Clinical Laboratory Testing Practices in Diffuse Gliomas Prior to Publication of 2021 World Health Organization Classification of Central Nervous System Tumors, Shakti H. Ramkissoon, Helen Fernandes, Dolores H. Lopez-Terrada, Meera R. Hameed, Dimitri G. Trembath, Julia A. Bridge, Neal I. Lindeman, Rhona J. Souers, Patricia Vasalos, Daniel J Brat, and Joel T. Moncur
Catabolic Ornithine Carbamoyltransferase Activity Facilitates Growth of Staphylococcus aureus in Defined Medium Lacking Glucose and Arginine, Itidal Reslane, Cortney R. Halsey, Amanda Stastny, Barbara J. Cabrera, Jong-Sam Ahn, Dhananjay Shinde, Madeline R. Galac, Margaret F. Sladek, Fareha Razvi, McKenzie K. Lehman, Kenneth W. Bayles, Vinai Chittezham Thomas, Luke D. Handke, and Paul D. Fey
Improved Database Filtering Technology Enables More Efficient Ab Initio Design of Potent Peptides against Ebola Viruses, Thomas Ripperda, Yangsheng Yu, Atul Verma, Elizabeth Klug, Michellie Thurman, St. Patrick Reid, and Guangshun Wang
Insect Cell Expression and Purification of Recombinant SARS-COV-2 Spike Proteins That Demonstrate ACE2 Binding, Lucas R. Struble, Audrey L. Smith, William E. Lutz, Gabrielle Grubbs, Satish Sagar, Kenneth W. Bayles, Prakash Radhakrishnan, Surender Khurana, Dalia El-Gamal, and Gloria E. O. Borgstahl
Biofilms: Formation, Research Models, Potential Targets, and Methods for Prevention and Treatment, Yajuan Su, Jaime T. Yrastorza, Mitchell Matis, Jenna Cusick, Siwei Zhao, Guangshun Wang, and Jingwei Xie
Type I IFN Signaling Protects Mice from Lethal SARS-CoV-2 Neuroinvasion., Md Bashir Uddin, Yuejin Liang, Shengjun Shao, Sunil Palani, Michael McKelvey, Scott C. Weaver, and Keer Sun
Exploring Epigenetic Reprogramming During Central Nervous System Infection, Zachary Van Roy and Tammy Kielian
IFN-γ Transforms the Transcriptomic Landscape and Triggers Myeloid Cell Hyperresponsiveness to Cause Lethal Lung Injury, Atul K. Verma, Michael McKelvey, Md Bashir Uddin, Sunil Palani, Meng Niu, Christopher Bauer, Shengjun Shao, and Keer Sun
Realistic and Critical Review of the State of Systemic Anti-Microbial Peptides, Guangshun Wang and Abraham F. Mechesso
Submissions from 2021
Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics, Christopher Campbell, Claire Fingleton, Merve S. Zeden, Emilio Bueno, Laura A Gallagher, Dhananjay Shinde, Jong-Sam Ahn, Heather M. Olson, Thomas L. Fillmore, Joshua N. Adkins, Fareha Razvi, Kenneth W. Bayles, Paul D. Fey, Vinai Chittezham Thomas, Felipe Cava, Geremy C. Clair, and James P. O'Gara
Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm, Sharon D.B. de Morais, Gunjan Kak, Joseph P. Menousek, and Tammy Kielian
Crosstalk Between Staphylococcus aureus and Innate Immunity: Focus on Immunometabolism, Christopher M. Horn and Tammy Kielian
The Prospect of Nanoparticle Systems for Modulating Immune Cell Polarization During Central Nervous System Infection, Lee E. Korshoj, Wen Shi, Bin Duan, and Tammy Kielian
Integrative Network Analyses of Transcriptomics Data Reveal Potential Drug Targets for Acute Radiation Syndrome, Robert Moore, Bhanwar Lal Puniya, Robert Powers, Chittibabu Guda, Kenneth W. Bayles, David B. Berkowitz, and Tomáš Helikar
The Evolution and Future of Targeted Cancer Therapy: From Nanoparticles, Oncolytic Viruses, and Oncolytic Bacteria to the Treatment of Solid Tumors, Kyle M. Pierce, William R. Miklavcic, Kyle P. Cook, Mikayla Sweitzer Hennen, Kenneth W. Bayles, Michael A. Hollingsworth, Amanda E. Brooks, Jessica E. Pullan, and Kaitlin M. Dailey
Structure and Activity of a Selective Antibiofilm Peptide SK-24 Derived from the NMR Structure of Human Cathelicidin LL-37, Yingxia Zhang, Jayaram Lakshmaiah Narayana, Qianhui Wu, Xiangli Dang, and Guangshun Wang
Submissions from 2020
TLR2 and Caspase-1 Signaling are Critical for Bacterial Containment But Not Clearance During Craniotomy-Associated Biofilm Infection, Amy L. Aldrich, Cortney E. Heim, Wen Shi, Rachel W. Fallet, Bin Duan, and Tammy Kielian
Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity, Megan E. Bosch, Blake P. Bertrand, Cortney E. Heim, Abdulelah A. Alqarzaee, Sujata S. Chaudhari, Amy L. Aldrich, Paul D. Fey, Vinai C. Thomas, and Tammy Kielian
Neutrophils are Mediators of Metastatic Prostate Cancer Progression in Bone, Diane L. Costanzo-Garvey, Tyler Keeley, Adam J. Case, Gabrielle F. Watson, Massar Alsamraae, Yangsheng Yu, Kaihong Su, Cortney E. Heim, Tammy Kielian, Colm Morrissey, Jeremy S Frieling, and Leah M. Cook
Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS, Elizabeth A. Delmain, Derek E. Moormeier, Jennifer L. Endres, Rebecca E. Hodges, Marat R. Sadykov, Alexander R. Horswill, and Kenneth W. Bayles
An Integrated Computational and Experimental Study to Investigate Staphylococcus Aureus Metabolism, Mohammad Mazharul Islam, Vinai Chittezham Thomas, Matthew Van Beek, Jong-Sam Ahn, Abdulelah A. Alqarzaee, Chunyi Zhou, Paul D. Fey, Kenneth W. Bayles, and Rajib Saha
Fluorescent Sensor Arrays Can Predict and Quantify the Composition of Multicomponent Bacterial Samples, Denis Svechkarev, Marat Sadykov, Lucas J. Houser, Kenneth W. Bayles, and Aaron M. Mohs
Monocyte Metabolic Reprogramming Promotes Pro-Inflammatory Activity and Staphylococcus Aureus Biofilm Clearance, Kelsey J. Yamada, Cortney E. Heim, Xinyuan Xi, Kuldeep S. Attri, Dezhen Wang, Wenting Zhang, Pankaj K. Singh, Tatiana K. Bronich, and Tammy Kielian
Submissions from 2019
Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix., Jeffrey S. Kavanaugh, Caralyn E. Flack, Jessica Lister, Erica B. Ricker, Carolyn B. Ibberson, Christian Jenul, Derek E. Moormeier, Elizabeth A. Delmain, Kenneth W. Bayles, and Alexander R. Horswill
Protease-Mediated Growth of Staphylococcus aureus on Host Proteins Is opp3 Dependent, McKenzie K. Lehman, Austin S. Nuxoll, Kelsey J. Yamada, Tammy Kielian, Steven D. Carson, and Paul D. Fey
Reanalysis of the NCCN PD-L1 Companion Diagnostic Assay Study for Lung Cancer in the Context of PD-L1 Expression Findings in Triple-Negative Breast Cancer, David L. Rimm, Gang Han, Janis M. Taube, Eunhee S. Yi, Julia A. Bridge, Douglas B. Flieder, Robert Homer, Anja C. Roden, Fred R. Hirsch, Ignacio I. Wistuba, and Lajos Pusztai
Observations of Shear Stress Effects on Staphylococcus aureus Biofilm Formation, Erica Sherman, Kenneth W. Bayles, Derek E. Moormeier, Jennifer L. Endres, and Timothy Wei
Urease is an Essential Component of the Acid Response Network of Staphylococcus Aureus and is Required for a Persistent Murine Kidney Infection, Chunyi Zhou, Fatema Bhinderwala, McKenzie K. Lehman, Vinai Chittezham Thomas, Sujata S. Chaudhari, Kelsey J. Yamada, Kirk W. Foster, Robert Powers, Tammy Kielian, and Paul D. Fey
Submissions from 2018
Oligomerization of Bacterially Expressed H1N1 Recombinant Hemagglutinin Contributes to Protection Against Viral Challenge, Tess E. Kuenstling, Anthony R. Sambol, Steven H. Hinrichs, and Marilynn A. Larson
Searching for Novel Biomarkers Using a Mouse Model of CLN3-Batten Disease, Derek Timm, Jacob T. Cain, Ryan D. Geraets, Katherine A. White, Seung Yon Koh, Tammy Kielian, David A. Pearce, Michelle L. Hastings, and Jill M. Weimer
Submissions from 2017
Gallium nanoparticles facilitate phagosome maturation and inhibit growth of virulent Mycobacterium tuberculosis in macrophages., Seoung-Ryoung Choi, Bradley E. Britigan, David M. Moran, and Prabagaran Narayanasamy
Novel long-chain compounds with both immunomodulatory and MenA inhibitory activities against Staphylococcus aureus and its biofilm., Seoung-Ryoung Choi, Joel Frandsen, and Prabagaran Narayanasamy
Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway., Joel Frandsen and Prabagaran Narayanasamy
Submissions from 2016
Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis., Ryan D. Geraets, Seung yon Koh, Michelle L. Hastings, Tammy Kielian, David A. Pearce, and Jill M. Weimer
IL-10 plays an important role in the control of inflammation but not in the bacterial burden in S. epidermidis CNS catheter infection., Yenis M. Gutierrez-Murgas, Gwenn Skar, Danielle Ramirez, Matthew Beaver, and Jessica N. Snowden
Membrane-Active Epithelial Keratin 6A Fragments (KAMPs) Are Unique Human Antimicrobial Peptides with a Non-αβ Structure., Judy T.Y. Lee, Guangshun Wang, Yu Tong Tam, and Connie Tam
Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia., Keer Sun, Vijaya Kumar Yajjala, Christopher Bauer, G. Talmon, Karl J. Fischer, Tammy Kielian, and Dennis W. Metzger
Submissions from 2015
Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy., Wei An, Scott A. Nadeau, Bhopal C. Mohapatra, Dan Feng, Neha Zutshi, Matthew D. Storck, Priyanka Arya, James E. Talmadge, Jane L. Meza, Vimla Band, and Hamid Band
Neuroinflammatory paradigms in lysosomal storage diseases., Megan Bosch and Tammy Kielian
Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma., Ning Ding, Xitao Li, Yunfei Shi, Lingyan Ping, Lina Wu, Kai Fu, Lixia Feng, Xiaohui Zheng, Yuqin Song, Zhengying Pan, and Jun Zhu
Primary sclerosing epithelioid fibrosarcoma of kidney with variant histomorphologic features: report of 2 cases and review of the literature., Dilek Ertoy Baydar, Kemal Kosemehmetoglu, Oguz Aydin, Julia A. Bridge, Berrin Buyukeren, and Fazil Tuncay Aki
Prolonged-acting, multi-targeting gallium nanoparticles potently inhibit growth of both HIV and mycobacteria in co-infected human macrophages., Prabagaran Narayanasamy, Barbara L. Switzer, and Bradley E. Britigan
Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin., Tyler D. Scherr, Mark L. Hanke, Ouwen Huang, David B.A. James, Alexander R. Horswill, Kenneth W. Bayles, Paul D. Fey, Victor J. Torres, and Tammy Kielian
Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses., Shweta Tripathi, Guangshun Wang, Mitchell White, Li Qi, Jeffery Taubenberger, and Kevan L. Hartshorn
Identifying the Critical Domain of LL-37 Involved in Mediating Neutrophil Activation in the Presence of Influenza Virus: Functional and Structural Analysis., Shweta Tripathi, Guangshun Wang, Mitchell White, Michael Rynkiewicz, Barbara Seaton, and Kevan Hartshorn
Antimicrobial Peptides in 2014., Guangshun Wang, Biswajit Mishra, Kyle Lau, Tamara Lushnikova, Radha Golla, and Xiuqing Wang
Submissions from 2014
Hemichannels in neurodegenerative diseases: is there a link to pathology?, Megan Bosch and Tammy Kielian
Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)., Maria Burkovetskaya, Nikolay Karpuk, Juan Xiong, Megan Bosch, Michael D. Boska, Hideyuki Takeuchi, Akio Suzumura, and Tammy Kielian
A central role for carbon-overflow pathways in the modulation of bacterial cell death., Vinai Chittezham Thomas, Marat Sadykov, Sujata S. Chaudhari, Joselyn Jones, Jennifer L. Endres, Todd J. Widhelm, Jong-Sam Ahn, Randeep S. Jawa, Matthew C. Zimmerman, and Kenneth W. Bayles
Classification of current anticancer immunotherapies., Lorenzo Galluzzi, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, and Guido Kroemer
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness., Mohammad-Saeid Jami, Jinxuan Hou, Miao Liu, M L. Varney, Hesham Hassan, Jixin Dong, Liying Geng, J. Wang, Fang Yu, Xin Huang, Hong Peng, Kai Fu, Yan Li, Rakesh Singh, and Shi-Jian Ding
Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group., Michael J. Monument, Kirsten M. Johnson, Elizabeth McIlvaine, Lisa Abegglen, W. Scott Watkins, Lynn B. Jorde, Richard B. Womer, Natalie Beeler, Laura Monovich, Elizabeth R. Lawlor, Julia A. Bridge, Joshua D. Schiffman, Mark D Krailo, R. Lor Randall, and Stephen L. Lessnick
Temporal and stochastic control of Staphylococcus aureus biofilm development., Derek E. Moormeier, Jeffrey L. Bose, Alexander R. Horswill, and Kenneth W. Bayles
Response of an aggressive periosteal aneurysmal bone cyst (ABC) of the radius to denosumab therapy., Chantal Pauli, Bruno Fuchs, Christian Pfirrmann, Julia A. Bridge, Silvia Hofer, and Beata Bode
Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity., Tyler D. Scherr, Cortney E. Heim, John M. Morrison, and Tammy Kielian
Expression of suppressor of cytokine signaling 1 (SOCS1) impairs viral clearance and exacerbates lung injury during influenza infection., Keer Sun, Sharon Salmon, Vijaya Kumar Yajjala, Christopher Bauer, and Dennis W. Metzger
Human Antimicrobial Peptides and Proteins, Guangshun Wang
Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds., Guangshun Wang, Mark L. Hanke, Biswajit Mishra, Tamara Lushnikova, Cortney E. Heim, Vinai Chittezham Thomas, Kenneth W. Bayles, and Tammy Kielian
Submissions from 2013
A dysfunctional tricarboxylic acid cycle enhances fitness of Staphylococcus epidermidis during β-lactam stress., Vinai Chittezham Thomas, Lauren C. Kinkead, Ashley Janssen, Carolyn R. Schaeffer, Keith M. Woods, Jill K. Lindgren, Jonathan M. Peaster, Sujata S. Chaudhari, Marat Sadykov, Joselyn Jones, Sameh M. Mohamadi AbdelGhani, Matthew C. Zimmerman, Kenneth W. Bayles, Greg A. Somerville, and Paul D. Fey
A genetic resource for rapid and comprehensive phenotype screening of nonessential Staphylococcus aureus genes., Paul D. Fey, Jennifer L. Endres, Vijaya Kumar Yajjala, Todd J. Widhelm, Robert J. Boissy, Jeffrey L. Bose, and Kenneth W. Bayles
Database-Guided Discovery of Potent Peptides to Combat HIV-1 or Superbugs., Guangshun Wang
Submissions from 2012
Contribution of the Staphylococcus aureus Atl AM and GL murein hydrolase activities in cell division, autolysis, and biofilm formation., Jeffrey L. Bose, McKenzie K. Lehman, Paul D. Fey, and Kenneth W. Bayles
MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection., Mark L. Hanke, Amanda Angle, and Tammy Kielian
Deciphering mechanisms of staphylococcal biofilm evasion of host immunity., Mark L. Hanke and Tammy Kielian
Low levels of β-lactam antibiotics induce extracellular DNA release and biofilm formation in Staphylococcus aureus., Jeffrey B. Kaplan, Era A. Izano, Prerna Gopal, Michael T. Karwacki, Sangho Kim, Jeffrey L. Bose, Kenneth W. Bayles, and Alexander R. Horswill
The Importance of Amino Acid Composition in Natural AMPs: An Evolutional, Structural, and Functional Perspective., Biswajit Mishra and Guangshun Wang
CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism., Austin S. Nuxoll, Steven M. Halouska, Marat Sadykov, Mark L. Hanke, Kenneth W. Bayles, Tammy Kielian, Robert Powers, and Paul D. Fey
Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection., Debbie Vidlak and Tammy Kielian
IL-1RI (interleukin-1 receptor type I) signalling is essential for host defence and hemichannel activity during acute central nervous system bacterial infection., Juan Xiong, Maria Burkovetskaya, Nikolay Karpuk, and Tammy Kielian
Submissions from 2011
Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274., Jinxuan Hou, Jixin Dong, Lijun Sun, Liying Geng, J. Wang, Jialin C. Zheng, Yan Li, Julia A. Bridge, Steven H. Hinrichs, and Shi-Jian Ding
Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity., Nikolay Karpuk, Maria Burkovetskaya, Teresa Fritz, Amanda Angle, and Tammy Kielian
Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus., Megan R. Kiedrowski, Jeffrey S. Kavanaugh, Cheryl L. Malone, Joe M. Mootz, Jovanka M. Voyich, Mark S. Smeltzer, Kenneth W. Bayles, and Alexander R. Horswill
MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection., Shuliang Liu and Tammy Kielian
Major families of multiresistant plasmids from geographically and epidemiologically diverse staphylococci., Julia E.S. Shearer, Joy Wireman, Jessica Hostetler, Heather Forberger, Jon Borman, John Gill, Susan Sanchez, Alexander Mankin, Jacqueline Lamarre, Jodi A. Lindsay, Kenneth W. Bayles, Ainsley Nicholson, Frances O'Brien, Slade O. Jensen, Neville Firth, Ronald A. Skurray, and Anne O. Summers
De Novo Design of Antiviral and Antibacterial Peptides with Varying Loop Structures, Guangshun Wang, Karen W. Buckheit, Biswajit Mishra, Tamara Lushnikova, and Robert W. Buckheit Jr.
Submissions from 2010
Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation., Karen E. Beenken, Lara N. Mrak, Linda M. Griffin, Agnieszka K. Zielinska, Lindsey N. Shaw, Kelly C. Rice, Alexander R. Horswill, Kenneth W. Bayles, and Mark S. Smeltzer
Submissions from 2009
MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses., Sarita Garg, Jessica R. Nichols, Nilufer Esen, Shuliang Liu, Nirmal K. Phulwani, Mohsin Md. Syed, William H. Wood, Yongqing Zhang, Kevin G. Becker, Amy Aldrich, and Tammy Kielian
Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus., Xianglu Li, William G. Fusco, Keun S. Seo, Kenneth W. Bayles, Erin E. Mosley, Mark A. McGuire, and Gregory A. Bohach
Assembly and development of the Pseudomonas aeruginosa biofilm matrix., Luyan Ma, Matthew Conover, Haiping Lu, Matthew R. Parsek, Kenneth W. Bayles, and Daniel J. Wozniak