ORCID (Optional)
https://orcid.org/0000-0001-8771-197X - Milan Terzic
https://orcid.org/0009-0002-9807-4819 - Yash Patel
Document Type
Case Report
Disciplines
Cardiology | Cardiovascular Diseases | Higher Education | Medicine and Health Sciences
Abstract
A 46-year-old bodybuilder presenting with new onset dyspnea found to have a new onset non-ischemic cardiomyopathy (CM) attributed to exogenous trenbolone and testosterone use. Steroid cessation and guideline-directed heart failure therapy led to notable recovery in left ventricular function supported by global longitudinal strain, ejection fraction and symptomatology.
Anabolic steroid-induced CM involves multiple mechanisms including lipid disturbances, hypertrophy, reduced receptor sensitivity, and cell damage. This case emphasizes the importance of recognizing anabolic steroid misuse as a potential cause of non-ischemic cardiomyopathy in middle aged men. With prompt discontinuation of steroids, remained abstinence and early initiation of guideline-directed medical therapy, myocardial recovery can occur.
DOI
https://doi.org/10.32873/unmc.dc.gmerj.6.2.003
Keywords
Trenbolone, Cardiomyopathy, Anabolic steroids, Testosterone, Heart Failure
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Recommended Citation
Terzic, M., , Patel, Y. B. Pumping Iron, Straining Hearts: Androgen Building Cardiomyopathy In a Middle Aged Bodybuilding Enthusiast. Graduate Medical Education Research Journal. 2024 Oct 31; 6(2).
https://digitalcommons.unmc.edu/gmerj/vol6/iss2/3
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