Submissions from 2024
Cross-Contamination of CRISPR Guides and Other Unrelated Nucleotide Sequences Among Commercial Oligonucleotides, Hiroshi Arakawa, Hiromi Miura, Rolen M. Quadros, Masato Ohtsuka, and Channabasavaiah B. Gurumurthy
SMARCA4 is a Haploinsufficient B Cell Lymphoma Tumor Suppressor That Fine-Tunes Centrocyte Cell Fate Decisions, Qing Deng, Priya Lakra, Panhong Gou, Haopeng Yang, Cem Meydan, Matthew Teater, Christopher Chin, Wenchao Zhang, Tommy Dinh, Usama Hussein, Xubin Li, Estela Rojas, Weiguang Liu, Patrick K. Reville, Atish Kizhakeyil, Darko Barisic, Sydney Parsons, Ashley Wilson, Jared Henderson, Brooks Scull, Channabasavaiah B. Gurumurthy, Francisco Vega, Amy Chadburn, Branko Cuglievan, Nader Kim El-Mallawany, Carl Allen, Christopher Mason, Ari Melnick, and Michael R. Green
Targeted Insertion of Conditional Expression Cassettes into the Mouse Genome Using the Modified i-PITT, Hiromi Miura, Ayaka Nakamura, Aki Kurosaki, Ai Kotani, Masaru Motojima, Keiko Tanaka, Shigeru Kakuta, Sanae Ogiwara, Yuhsuke Ohmi, Hirotaka Komaba, Samantha L. P. Schilit, Cynthia C. Morton, Channabasavaiah B. Gurumurthy, and Masato Ohtsuka
Investigation into Cardiac Myhc-α 334-352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity, Meghna Sur, Mahima T. Rasquinha, Kiruthiga Mone, Chandirasegaran Massilamany, Ninaad Lasrado, Channabasavaiah B. Gurumurthy, Raymond A Sobel, and Jay Reddy
Submissions from 2023
Rescue of auditory function by a single Administration of AAV-TMPRSS3 Gene Therapy in Aged Mice of Human Recessive Deafness DFNB8, Wan Du, Volkan Ergin, Corena Loeb, Mingqian Huang, Stewart Silver, Ariel Miura Armstrong, Zaohua Huang, Channabasavaiah B. Gurumurthy, Hinrich Staecker, Xuezhong Liu, and Zheng-Yi Chen
Molecular Subtyping and Survival Analysis of Osteosarcoma Reveals Prognostic Biomarkers and Key Canonical Pathways, Siddesh Southekal, Sushil Kumar Shakyawar, Prachi Bajpai, Amr Elkholy, Upender Manne, Nitish Kumar Mishra, and Chittibabu Guda
Transgenic Mice Expressing Functional TCRs Specific to Cardiac Myhc-α 334-352 on Both CD4 and CD8 T Cells Are Resistant to the Development of Myocarditis on C57BL/6 Genetic Background, Meghna Sur, Mahima T. Rasquinha, Rajkumar Arumugam, Chandirasegaran Massilamany, Arunkumar Gangaplara, Kiruthiga Mone, Ninaad Lasrado, Bharathi Yalaka, Aakash Doiphode, Channabasavaiah B. Gurumurthy, David Steffen, and Jay Reddy
A Facile Strategy for the Fabrication of Cell-Laden Porous Alginate Hydrogels based on Two-Phase Aqueous Emulsions, Wen Xue, Donghee Lee, Yunfan Kong, Mitchell A. Kuss, Ying Huang, Taesung Kim, Soonkyu Chung, Andrew T. Dudley, Seung-hyun Ro, and Bin Duan
Submissions from 2022
Extracellular Mechanotransduction, Stephen J. Haller and Andrew T. Dudley
mintRULS: Prediction of miRNA-mRNA Target Site Interactions Using Regularized Least Square Method, Sushil Kumar Shakyawar, Siddesh Southekal, and Chittibabu Guda
Submissions from 2021
FGDB: Database of Follicle Stimulating Hormone Glycans, Sushil Kumar Shakyawar, Sanjit Pandey, David J. Harvey, George Bousfield, and Chittibabu Guda
Submissions from 2020
Red Panda: A Novel Method for Detecting Variants in Single-Cell RNA Sequencing, Adam Cornish, Shrabasti Roychoudhury, Krishna Sarma, Suravi Pramanik, Kishor Bhakat, A T. Dudley, Nitish K. Mishra, and Chittibabu Guda
Steered Molecular Dynamic Simulations Reveal Marfan Syndrome Mutations Disrupt Fibrillin-1 cbEGF Domain Mechanosensitive Balcium Binding, Stephen J. Haller, Adrian E. Roitberg, and Andrew T. Dudley
Long Non-Coding RNA Profiling of Pediatric Medulloblastoma, Varun Kesherwani, Mamta Shukla, Don W. Coulter, J. Graham Sharp, Shantaram Joshi, and Nagendra K. Chaturvedi
Exosomes Secreted Under Hypoxia Enhance Stemness in Ewing's Sarcoma Through miR-210 Delivery, Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, and Shantaram S. Joshi
Submissions from 2019
Characterization of the Plasma Proteome of Nonhuman Primates During Ebola Virus Disease or Melioidosis: A Host Response Comparison, Michael D. Ward, Ernst E. Brueggemann, Tara Kenny, Raven E. Reitstetter, Christopher R. Mahone, Sylvia Trevino, Kelly Wetzel, Ginger C. Donnelly, Cary Retterer, Robert B. Norgren, Rekha G. Panchal, Travis K. Warren, Sina Bavari, and Lisa H. Cazares
Submissions from 2018
Sooty Mangabey Genome Sequence Provides Insight into AIDS Resistance in a Natural SIV Host, David Palesch, Steven E. Bosinger, Gregory K. Tharp, Thomas H. Vanderford, Mirko Paiardini, Ann Chahroudi, Zachary P. Johnson, Frank Kirchhoff, Beatrice H. Hahn, Robert B. Norgren, Nirav B. Patel, Donald L. Sodora, Reem A. Dawoud, Caro-Beth Stewart, Sara M. Seepo, R. Alan Harris, Yue Liu, Muthuswamy Raveendran, Yi Han, Adam English, Gregg W.C. Thomas, Matthew W. Hahn, Lenore Pipes, Christopher E. Mason, Donna M. Muzny, Richard A. Gibbs, Daniel Sauter, Kim Worley, Jeffrey Rogers, and Guido Silvestri
Preliminary Studies on Immune Response and Viral Pathogenesis of Zika Virus in Rhesus Macaques, Shawna M. Woollard, Omalla A. Olwenyi, Debashis Dutta, Rajnish S. Dave, Saumi Mathews, Santhi Gorantla, Noel Johnson, Luis Giavedoni, Robert B. Norgren, and Siddappa N. Byrareddy
Submissions from 2017
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage., Marketa Kaucka, Tomas Zikmund, Marketa Tesarova, Daniel Gyllborg, Andreas Hellander, Josef Jaros, Jozef Kaiser, Julian Petersen, Bara Szarowska, Phillip T. Newton, Vyacheslav Dyachuk, Lei Li, Hong Qian, Anne-Sofie Johansson, Yuji Mishina, Joshua D. Currie, Elly M. Tanaka, Alek Erickson, A T. Dudley, Hjalmar Brismar, Paul Southam, Enrico Coen, Min Chen, Lee S. Weinstein, Ales Hampl, Ernest Arenas, Andrei S. Chagin, Kaj Fried, and Igor Adameyko
Submissions from 2016
Exome Screening to Identify Loss-of-Function Mutations in the Rhesus Macaque for Development of Preclinical Models of Human Disease, Adam Cornish, Robert M. Gibbs, and Robert B. Norgren
Exome-based Variant Detection in Core Promoters., Yeong C. Kim, Jian Cui, Jiangtao Luo, Fengxia Xiao, Bradley Downs, and San Ming Wang
Prevalence and spectrum of BRCA germline variants in mainland Chinese familial breast and ovarian cancer patients., Yeong C. Kim, Linli Zhao, Hanwen Zhang, Ye Huang, Jian Cui, Fengxia Xiao, Bradley Downs, and San Ming Wang
Submissions from 2015
Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening., Channabasavaiah B. Gurumurthy, Poonam S. Joshi, Scott G. Kurz, Masato Ohtsuka, Rolen M. Quadros, Donald W. Harms, and K.C. Kent Lloyd
De Novo Assembly of the Chimpanzee Transcriptome from NextGen mRNA Sequences, Mnirnal D. Maudhoo, Jacob D. Madison, and Robert B. Norgren
CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA., Hiromi Miura, Channabasavaiah B. Gurumurthy, Takehito Sato, Masahiro Sato, and Masato Ohtsuka
Assessment of Artificial MiRNA Architectures for Higher Knockdown Efficiencies without the Undesired Effects in Mice., Hiromi Miura, Hidetoshi Inoko, Masafumi Tanaka, Hirofumi Nakaoka, Minoru Kimura, Channabasavaiah B. Gurumurthy, Masahiro Sato, and Masato Ohtsuka
One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT)., Masato Ohtsuka, Hiromi Miura, Keiji Mochida, Michiko Hirose, Ayumi Hasegawa, Atsuo Ogura, Ryuta Mizutani, Minoru Kimura, Ayako Isotani, Masahito Ikawa, Masahiro Sato, and Channabasavaiah B. Gurumurthy
Insertion of sequences at the original provirus integration site of mouse ROSA26 locus using the CRISPR/Cas9 system., Rolen M. Quadros, Donald W. Harms, Masato Ohtsuka, and Channabasavaiah B. Gurumurthy
Discovering Distinct Functional Modules of Specific Cancer Types Using Protein-Protein Interaction Networks., Ru Shen, Xiaosheng Wang, and Chittibabu Guda
GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice., Gou Takahashi, Channabasavaiah B. Gurumurthy, Kenta Wada, Hiromi Miura, Masahiro Sato, and Masato Ohtsuka
Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model., Shikha Tarang, Songila M.S.R Doi, Channabasavaiah B. Gurumurthy, Donald W. Harms, Rolen M. Quadros, and Sonia M. Rocha-Sanchez
Submissions from 2014
Computational analysis of transcriptional circuitries in human embryonic stem cells reveals multiple and independent networks, Xiaosheng Wang and Chittibabu Guda
A New Rhesus Macaque Assembly and Annotation for Next-Generation Sequencing Analyses, Aleksey V. Zimin, Adam S. Cornish, Mnirnal D. Maudhoo, Robert M. Gibbs, Xiongfei Zhang, Sanjit Pandey, Daniel T. Meehan, Kristin Wipfler, Steven E. Bosinger, Zachary P. Johnson, Gregory K. Tharp, Guillaume Marçais, Michael Roberts, Betsy Ferguson, Howard S. Fox, Todd Treangen, Steven L. Salzberg, James A. Yorke, and Robert B. Norgren
Submissions from 2013
Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients., Sameer Mirza, Emad A. Rakha, Alaa Alshareeda, Shakur Mohibi, Xiangshan Zhao, Bryan J. Katafiasz, Jun Wang, Channabasavaiah B. Gurumurthy, Aditya Bele, Ian O. Ellis, Andrew R. Green, Hamid Band, and Vimla Band
Heterogeneity of functional properties of clone 66 murine breast cancer cells expressing various stem cell phenotypes, Partha Mukhopadhyay, Tracy Farrell, Gayatri Sharma, Timothy R. McGuire, Barbara O'Kane, and J. Graham Sharp
Discovery of molecular associations among aging, stem cells, and cancer based on gene expression profiling., Xiaosheng Wang
Identification of potential synthetic lethal genes to p53 using a computational biology approach, Xiaosheng Wang and Richard Simon
The genome of polymorphonuclear neutrophils maintains normal coding sequences, Fengxia Xiao, Yeong C. Kim, Hongxiu Wen, Jiangtao Luo, Pei Xian Chen, Kenneth Cowan, and San Ming Wang
Submissions from 2012
Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression., Shakur Mohibi, Channabasavaiah B. Gurumurthy, Alo Nag, Jun Wang, Sameer Mirza, Yousaf Mian, Meghan Quinn, Bryan J. Katafiasz, James D. Eudy, Sanjit Pandey, Chittibabu Guda, Mayumi Naramura, Hamid Band, and Vimla Band
New fusion transcripts identified in normal karyotype acute myeloid leukemia, Hongxiu Wen, Yongjin Li, Sami N. Malek, Yeong C. Kim, Jia Xu, Pei Xian Chen, Fengxia Xiao, Xin Huang, Xianzheng Zhou, Zhenyu Xuan, Shiva Mankala, Guihua Hou, Janet D. Rowley, Michael Q. Zhang, and San Ming Wang
Limitations of the Rhesus Macaque Draft Genome Assembly and Annotation, Xiongfei Zhang, Joel Goodsell, and Robert B. Norgren
Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients., Xiangshan Zhao, Sameer Mirza, Alaa Alshareeda, Ying Zhang, Channabasavaiah B. Gurumurthy, Aditya Bele, Jun Hyun Kim, Shakur Mohibi, Monica Goswami, Subodh M. Lele, William West, Fang Qiu, Ian O. Ellis, Emad A. Rakha, Andrew R. Green, Hamid Band, and Vimla Band
Submissions from 2011
Computational analysis of expression of human embryonic stem cell-associated signatures in tumors., Xiaosheng Wang
Microarray-based cancer prediction using single genes., Xiaosheng Wang and Richard Simon
Submissions from 2010
Large Scale Analysis of Positional Effects of Single-Base Mismatches on Microarray Gene Expression Data, Fenghai Duan, Mark A. Pauley, Eliot R. Spindel, Li Zhang, and Robert B. Norgren
A robust gene selection method for microarray-based cancer classification., Xiaosheng Wang and Osamu Gotoh
Inference of cancer-specific gene regulatory networks using soft computing rules., Xiaosheng Wang and Osamu Gotoh
Submissions from 2009
Role of mammalian Ecdysoneless in cell cycle regulation., Jun Hyun Kim, Channabasavaiah B. Gurumurthy, Mayumi Naramura, Ying Zhang, Andrew T. Dudley, Lynn Doglio, Hamid Band, and Vimla Band
Accurate molecular classification of cancer using simple rules., Xiaosheng Wang and Osamu Gotoh
Microarray-based cancer prediction using soft computing approach., Xiaosheng Wang and Osamu Gotoh
Submissions from 2008
Gene Targeting in Adult Rhesus Macaque Fibroblasts, Daniel T. Meehan, Mary Ann Zink, Melissa Mahlen, Marilu Nelson, Warren G. Sanger, Shoukhrat M. Mitalipov, Don P. Wolf, Michel M. Ouellette, and Robert B. Norgren
Submissions from 2007
Intercenter Reliability and Validity of the Rhesus Macaque GeneChip, Fenghai Duan, Eliot R. Spindel, Yu-Hua Li, and Robert B. Norgren
Single Nucleotide Polymorphisms (SNPs) Distinguish Indian-Origin and Chinese-Origin Rhesus Macaques (Macaca Mulatta), Betsy Ferguson, Summer L. Street, Hollis Wright, Carlo Pearson, Yibing Jia, Shaun L. Thompson, Patrick Allibone, Christopher J. Dubay, Eliot Spindel, and Robert B. Norgren
Submissions from 2005
Leveraging Human Genomic Information to Identify Nonhuman Primate Sequences for Expression Array Development, Eliot R. Spindel, Mark A. Pauley, Yibing Jia, Courtney Gravett, Shaun L. Thompson, Nicholas F. Boyle, Sergio R. Ojeda, and Robert B. Norgren
Submissions from 2004
Creation of Non-Human Primate Neurogenetic Disease Models by Gene Targeting and Nuclear Transfer, Robert B. Norgren
Submissions from 1999
Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchyme., Andrew T. Dudley, R. E. Godin, and E. J. Robertson
Submissions from 1995
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye., Andrew T. Dudley, K. M. Lyons, and E. J. Robertson