Chronic invasive fungal sinusitis (CIFS) is defined as fungal invasion of the sinonasal submucosa for greater than 12 weeks. Common causes are dematiaceous molds followed by Aspergillus species, but can rarely be caused by other pathogens
A 71-year-old immunocompetent male presented with orbital apex syndrome found to be due to chronic invasive fungal sinusitis caused by Scedosporium apiospermum. After surgical debridement and appropriate systemic antifungal therapy, he made a near full recovery.
Scedosporium apiospermum is an emerging pathogen and a rare cause of chronic invasive fungal sinusitis. The diagnostic and treatment dilemmas involved with this rare but emerging clinical entity will be discussed.
Chronic invasive fungal sinusitis, invasive fungal sinusitis, rhinology, orbital apex syndrome, endoscopic sinus surgery, scedosporium apiospermum
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Christensen, D. N., Barnes, C., , Miller, M. Chronic Invasive Fungal Sinusitis due to Scedosporium Apiospermum causing Orbital Apex Syndrome. Graduate Medical Education Research Journal. 2021 Oct 04; 3(1).