ORCID (Optional)


Document Type

Original Report


Higher Education | Medicine and Health Sciences | Therapeutics


Introduction: Stereotactic radiosurgery (SRS) is an excellent option for the treatment of numerous central nervous system diseases. There exist several forms of SRS, including gamma-knife surgery (GKS) and cyber-knife surgery. The most significant complication of SRS is the delayed effects of therapeutic radiation, also known as radionecrosis. The current treatment options for radionecrosis have a significant side effect profile and posit challenges for medical management. More recently, hyperbaric oxygen therapy (HBO2) has emerged as an option for treatment with minimal side effects.

Methods: We present a retrospective case series examining ten patients treated with HBO2 after receiving radiotherapy. Of these cases, six were treated with GKS, two were treated with cyber-knife surgery, and two with Intensity-modulated radiation therapy (IMRT).

Results: In all ten cases, the patients reported significant improvement in clinical symptoms.

Conclusions: These cases demonstrate the efficacy of HBO2 as a treatment for cerebral radionecrosis.




Hyperbaric oxygen therapy, stereotactic radiation, cyber-knife surgery, gamma-knife surgery, cerebral necrosis

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Table AVM HBO.docx (14 kB)
table 1

figure 1.docx (293 kB)
fig 1

figure 2.docx (362 kB)
fig 2

figure 3.docx (198 kB)
fig 3

figure 4.docx (224 kB)
fig 4



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