Higher Education | Medicine and Health Sciences | Therapeutics
Introduction: Stereotactic radiosurgery (SRS) is an excellent option for the treatment of numerous central nervous system diseases. There exist several forms of SRS, including gamma-knife surgery (GKS) and cyber-knife surgery. The most significant complication of SRS is the delayed effects of therapeutic radiation, also known as radionecrosis. The current treatment options for radionecrosis have a significant side effect profile and posit challenges for medical management. More recently, hyperbaric oxygen therapy (HBO2) has emerged as an option for treatment with minimal side effects.
Methods: We present a retrospective case series examining ten patients treated with HBO2 after receiving radiotherapy. Of these cases, six were treated with GKS, two were treated with cyber-knife surgery, and two with Intensity-modulated radiation therapy (IMRT).
Results: In all ten cases, the patients reported significant improvement in clinical symptoms.
Conclusions: These cases demonstrate the efficacy of HBO2 as a treatment for cerebral radionecrosis.
Hyperbaric oxygen therapy, stereotactic radiation, cyber-knife surgery, gamma-knife surgery, cerebral necrosis
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Prathivadhi-Bhayankaram, S., , cooper, j. S. Hyperbaric Oxygen Therapy for Cerebral Radiation Necrosis Secondary to Stereotactic Radiation: A Case Series. Graduate Medical Education Research Journal. 2022 Jul 14; 4(1).