ORCID (Optional)
https://orcid.org/
0000-0001-7686-361X
Document Type
Case Report
Disciplines
Equipment and Supplies | Higher Education | Medicine and Health Sciences | Surgery | Therapeutics
Abstract
Introduction
Previously irradiated tissue is characterized by changes including decreased vascularity, impaired cellular proliferation, and local hypoxia consistent with fibroblastic atrophy which can persist long after radiation therapy. Hyperbaric oxygen therapy has been shown to be beneficial in the treatment of complications arising from these late effects of radiation on normal tissue through enhancing fibroblast proliferation, collagen maturation, stem cell recruitment, and angiogenesis.
Methods
We report on three patients with debilitating radiation enterocolitis causing issues including recurrent bowel obstruction, anorexia requiring total parenteral nutrition, pain, diarrhea, fecal incontinence, dehydration, and malnutrition.
Results
In all three cases marked improvement was the outcome with hyperbaric treatment.
Conclusion
Hyperbaric oxygen therapy should be routinely considered in the treatment of radiation-induced enteritis or colitis.
DOI
10.32873/unmc.dc.gmerj.4.1.008
Keywords
late radiation effects; radiation colitis; radiation enteritis; hyperbaric oxygen
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Recommended Citation
Ringle, M. D., , cooper, j. S. Successful Treatment of Radiation-Induced Colitis and Enteritis with Hyperbaric Oxygen Therapy. Graduate Medical Education Research Journal. 2022 Jul 14; 4(1).
https://digitalcommons.unmc.edu/gmerj/vol4/iss1/10
Included in
Equipment and Supplies Commons, Higher Education Commons, Surgery Commons, Therapeutics Commons
