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Theses/Dissertations from 2022

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The Development of Thermoresponsive Hydrogel-Based Drug Delivery Systems for the Treatment of Musculoskeletal Diseases, Ningrong Chen

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Omics Analysis in Cancer and Development, Emalie J. Clement

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Leukocyte Subsets in the Peripheral Blood and Spleen of Gastrointestinal Cancer Patients, Kathryn E. Cole

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Roles of C-Terminal Domain of DNA Polymerase ζ Catalytic Subunit, Rev3, in Translesion Dna Synthesis and Origin of Mutations in Yeast, Jian Cui

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Mechanisms of Sorting and Fission at the Endosomes, Kanika Dhawan

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The Link Between Fat Soluble Vitamin Deficiencies, Decreased Microbiota Diversity and Severity in Children with Sickle Cell Disease Followed in a Clinic in Omaha Nebraska, Chinenye R. Dike

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Development of Perfluorocarbon Nanoemulsions for Delivery of Therapeutic Nucleic Acids, Ling Ding

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Linking spinal cord circuits with upper limb sensorimotor control in adults with cerebral palsy, Saihari Dukkipati

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Evaluation of Awareness, Knowledge, and Preventive Intervention of Nonalcoholic Fatty Liver Disease Among Chinese Young Adults, Yi Du

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Psychological Trauma Alters T-lymphocyte Inflammation and Redox Through Sympathetic Mechanisms, Safwan K. Elkhatib

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Teaching Children with Autism Spectrum Disorder Self-Protection Skills in Response to Bullying Situations, Maya J. Fallon

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Feasibility and Efficacy of Bisphosphonate Use for the Prevention of Bone and Muscle Loss, Laura E. Flores

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Role of E3 Ubiquitin Ligase UBR5 in B Cell Development and Mantle Cell Lymphoma, Tyler J. Gilbreath

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A systematic literature review of the prevalence, distribution, exposure, and human health risks of tire microplastics and the contribution of their physicochemically diverse properties, Luke Glastad

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Investigating the Role of Splenic Macrophages in Pancreatic Cancer, Daisy V. Gonzalez

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ERα as a Modulator of the Sle1b Lupus Susceptibility Locus and B Cell Receptor Signaling, Jared H. Graham

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Investigation of Cumulative Genetic Risk and CC16 in Adult Asthma and COPD Populations, Kelli C. Gribben

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Characterizing a MUC4-Based Nanovaccine and Enhancing its Efficacy by Targeting the Endothelin Axis, Mansi Gulati

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Prenatal and Pregnancy Loss Evaluation by Noninvasive Screening and Diagnostic Genetic Testing, Abigail Haggerty

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Extracellular Mechanotransduction in Marfan Syndrome: An Equivalence Principle, Stephen Haller

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Frailty and Neurocognition in Prostate Cancer, Lindsey Hanson

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Regulation of Pancreatic Cancer Progression by Micronutrients, Chunbo He

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Neuropilin-2 in Advanced Prostate Cancer and its Targeting with Novel Small Molecule Inhibitors, Ridwan Islam

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Structural and Biochemical Studies of Three Enzymes Involved in Amino Acid Metabolism to Develop Novel Drugs, Yahani Pankaja Jayasinghe Arachchige

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Structural and Inhibitory Studies on (i)Two Mycobacterium Tuberculosis Enzymes Essential for Capsular Glucan Biosynthesis and mRNA Degradation: (Ii) Hantann Virus L-Protein Endonuclease Domain, Hettiarachchige Thilina D. Jayasinghe

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An Analysis of the Genetic and Environmental Mechanisms behind Aortic Aneurysm Development and Inhibition, Kathryn E. Jespersen

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Aerosols in Orthodontics: Characterization of Particle Size and Travel Distance, Donte Jochum-Nesbitt

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Strengthening Capacity for Clinical and Translational Science: A Multi-Method Assessment of Research Capacity Development in a Regional Clinical and Translational Research Network, LaKaija Johnson

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Gut Commensals Modulate SIV/SHIV Pathogenesis and Therapeutics, Samuel Johnson

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Novel Molecular Mechanisms of C-Terminal Eps15 Homology Domain (EHD) Proteins in Endocytic Trafficking and Primary Ciliogenesis, Tyler M. Jones

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Determining the Role of miR-133a in the Diabetic Heart, Tyler Kambis

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Polymeric Chloroquine in Metastatic Pancreatic Cancer Therapy, Rubayat Islam Khan

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Evaluating Targets and Therapeutics for the Treatment of Pancreatic Cancer, Shelby M. Knoche

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Returning to Life Activities after Hematopoietic Cell Transplantation in Older Adults, Thuy T. Koll

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Ewing Sarcoma Transcriptome: Identification of FOXN3 as a Novel Target of EWS-FLI1, Natasha Kreiling

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Mental Health Promotion, Early Identification & Treatment Services and Supports in Public K-12 School Districts: Three Case Studies to Explore Available Resources, Interventions, and Community Partnerships, Keenan Krick

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Formal Caregiver Burden among Nursing Assistants in Nursing Homes: A Mixed Methods Study, Rachel Kunkle

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Understanding the Perceived Risk and Biopsychosocial Impact of the COVID-19 Pandemic on People Living with HIV and Pre-Exposure Prophylaxis Users in Nebraska: A Mixed Methods Approach, Titilola O. Labisi

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Increasing Young Children’s Honest Reports and Decreasing Their Transgressions, Robert K. Lehardy

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The Role of Parkin in Mitochondrial DNA, Eliezer Lichter

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Overcome Resistance to Drug-Induced Apoptosis in Cancer Cells, Jian Li

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Characterization of 1,1-Diarylethylene FOXM1 Inhibitors Against High-Grade Serous Ovarian Carcinoma Cells, Cassie Liu

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Novel Mechanisms of Protein Kinase C α Regulation and Function, Xinyue Li

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Macromolecular Fluorescent Conjugates for Bioimaging Applications, Paul Lovell

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Essential Protections for Essential Workers: Ethical Considerations for Infection Prevention and Control, Abigail E. Lowe

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Underlying Mechanism of Ovarian Reserve Preservation from Gonadotoxicity, Yi Luan

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Assessing the Methodology, Prevalence, and Associated Factors for Adverse Childhood Experiences (ACEs) Among Children and Adolescents in the United States, Kiara L. Lyons

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CRISPR Technology as an Antiviral in dsDNA and ssRNA Viruses, Cathryn Mayes

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Mobile, Biosensor Technology for Measuring Joint-Level Human Motion, Matthew McManigal

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SOX2 Dosage Governs Tumor Cell Identity and Proliferation, Ethan P. Metz

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The Effect of Interproximal Home Regimens of Inflammatory Biomarkers in Periodontal Maintenance Patients, Grace Moore

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Exploring Host-Pathogen Interactions of the Ebola Virus Ribonucleoprotein Complex, M. Jane Morwitzer

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The Role of Calprotectin in T-Lymphocyte Driven Inflammation in a Mouse Model of Psychological Trauma, Cassandra Moshfegh

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Innate Immunity in the Pathobiology and Treatment of Infectious and Neurodegenerative Diseases, Mai Mostafa

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Hepatocyte-Hepatic Stellate Cell Axis in Potentiation of Alcohol and HIV-Induced Liver Injury, Moses O. New-Aaron

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Modulating Cellular Senescence to Improve Age-Associated Wound Healing Impairment, Upasana Niyogi

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Agrichemicals (Nitrate and Atrazine) In Drinking Water and Adverse Health Outcomes in Children in Nebraska, Balkissa S. Ouattara

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Establishing a generalized qualifying autoclitic repertoire in children with autism spectrum disorder, Todd M. Owen

Investigating the Role of Sphingosine Kinases During Alphavirus Infection, Opeoluwa Oyewole

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Investigating the Role of Sphingosine Kinases During Alphavirus Infection, Opeoluwa Oyewole

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The Development and In Vivo Immunologic Assessment of Biodegradable Microparticles Incorporating CPDI-02 and Mucosal Protein Vaccine, Jacob E. Parriott

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Evaluation of medication optimization in the setting of ECMO therapy: assessment of therapeutic effectiveness, Greg Peitz

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Applications of Population Pharmacokinetic Modeling in People Living with HIV, Michelle M. Pham

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Optimizing Antiretroviral Therapy with Modern Rifapentine Containing TB Treatment, Anthony T. Podany

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1-Check UNMC Mobile App Usage: A Quantitative Analysis of the Data, Molly Pofahl

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Characterization of APE1 And DNA G-Quadruplex Interaction in Transcription Regulation and DNA Damage Repair, Suravi Pramanik

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Environmental exposures and human health challenges: Evidence-based insights from health surveillance systems, Jagadeesh Puvvula

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Tourniquet-induced ischemia-reperfusion Injury, Junliang Qian

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The Relationship between p66Shc Expression and Proliferation of Human Prostate Cancer Cells with MnTnBuOE-2-PyP Treatment, Thao Nhi Radik

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Teachering Protective Skills to Address Risk Factors Associated with Emerging Problem Behavior, Javid A. Rahaman

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Post-Transcriptional Control of the Epithelial-to-Mesenchymal Transition (EMT) in Ras-Driven Colorectal Cancers, Chaitra Rao

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PAF1/PD2 Augments Pancreatic Cancer Progression and Mediates Radiation and Chemoresistance, Sanchita Rauth

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Frailty Determination and Responsiveness in Left Ventricular Assist Devices, Sarah Schroeder

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Design, Synthesis, and Biological Investigation of Pyridine Sulfones as Anti-Chlamydia trachomatis Agents, Mohamed A. Seleem

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Gender Differences in Breast Cancer Treatment Decisions and Related Survival: A Study Using the National Cancer Database, Shamim Shahi

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Fabrication and Characterization of Porous Biomaterial for Potential Antigen Delivery, Farah Shahjin

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Building an Artificial Intelligence Framework for Hypertension Diagnosis: A Use Case of the Problem List Curation, Ketemwabi Yves Shamavu

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The Effect of Interproximal Home Oral Hygiene on Clinical Parameters in Periodontal Maintenance Patients, Kevin T. Smith

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Dysregulation of miR-10a Promotes Cancer Features in Cholangiocarcinoma, Matthieu Spriet

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Maternal Distress in the Neonatal Intensive Care Unit, Morgan A. Staver

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Dynamics of Nucleosome Assembly Characterized by Atomic Force Microscopy, Tommy Stormberg

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Contextual Factors and STI/HIV Sexual Risk Behaviors Among Hispanic Youths aged 13 to 24 years, Mariam Taiwo

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Development of Bioactive Polymers for Anticancer siRNA Therapy, Siyuan Tang

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Genome-Wide Distribution of Acape1 and Its Implications in DNA Repair and Transcription, Mason Tarpley

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Depression and Parenting: A Mixed Method Analysis of Some Protective Factors for Depression Among African American Fathers Using a Community-Based Participatory Research Approach, Tatiana Tchouankam

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Use of Machine Learning Algorithms and Highly Multiplexed Immunohistochemistry to Perform In-Depth Characterization of Primary Pancreatic Tumors and Metastatic Sites, Krysten Vance

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Characterization of Metastatic Cutaneous Squamous Cell Carcinoma in the Immunosuppressed Patient, Megan E. Wackel

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Ethical Sensitivity of PADIS Care Among Critical Care Nurses: A Mixed Methods Study, Denise Waterfield

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A Study to Determine the Most Important Leadership Skills for Entry-Level Public Health Practitioners, Taelyr Weekly

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The Role of Ubiquitin E3 Ligase FBXO21 in Steady-State, Stressed, and Malignant Hematopoiesis, Karli J. Wittorf

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Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling, Pauline Xu

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Modulation of Immune Homeostasis in Neurodegenerative Diseases, Pravin Yeapuri

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Nanofabrication for Precision Vaccinology, Karen Zagorski

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Phos-Tag-Based Screens Identify Novel Therapeutic Targets in Ovarian Cancer and Pancreatic Cancer, Renya Zeng

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Targeting Androgen Receptor on Glioblastoma, Nan Zhao

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The Development of Polymeric Dexamethasone Prodrug Nanomedicines for the Treatment of Lupus Nephritis, Zhifeng Zhao

Theses/Dissertations from 2021

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The Ecology of Mental Health and the Impact of Barriers on Mental Health Service Utilization, Alisha Aggarwal

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Alignment of Cervical Vertebrae and Reliability of Cephalometric Measurements, Ece Agirgol

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Factors Associated with Omani’s Schoolteachers’ Reporting Behavior of Suspected Cases of Child Abuse and Neglect, Zeinab N. Alazri

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Giving Birth at a Critical Time: Assessing Perinatal Depression Among Syrian Refugees in Low Resource Settings, Nada Alnaji