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Theses/Dissertations from 2026

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Novel Approaches for Environmental Surveillance of Viral Aerosols: Detection, Characterization, and Analysis, Daniel Ackerman

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Evaluating FOXM1 Hydrophobic Tag Degraders in High-Grade Serous Ovarian Cancer Cells, Tania Aguilera Pineda

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Engineering Approaches to Promote Peripheral Nerve Injury and Denervated Muscle Regeneration, Olawale Alimi

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Design, Synthesis, and Evaluation of Putative B7-H3 Inhibitors for Group 3 Medulloblastoma, Hamdan Alrefaei

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Promoting Social Communicative Gestures by Minimally Verbal Children with Autism, Rebecca J. Barall

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Replication and Extension of KRAS-Associated Gene Expression Signatures in Lung Adenocarcinoma: A Cox Proportional Hazards Analysis of Mutation Status, Gene Expression, Multi-Gene Mutation Count, and RAS de Novo Signature, Camryn Berry

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KSR1 Mediates SCLC Tumor Initiation and Cisplatin Resistance, Deepan Chatterjee

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Promoter G-Quadruplexes Scaffold Apurinic/Apyrimidinic Endonuclease 1 (APE1) to Promote Oncogene Expression in Triple-Negative Breast Cancer, Yingling Chen

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Development of Water-Soluble Nanofibrous Poly(Vinyl Alcohol) Collectors for Bioaerosol Sampling and Environmental Surface Microbial Detection, Kevin Crown

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Therapeutic Strategies in Glioblastoma and Acute Kidney Injury: Androgen Receptor-Directed Therapy for High-Grade Glioma and Nanoparticle-Based Therapeutic Strategies for Cisplatin-Induced Nephrotoxicity, Ashish Das

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Molecular and Structural Determinants of Ovarian Aging, Dipanwita Das

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Optimization of the Near-Infrared Fluorescence Probe: HuAR9.6-IRDye800 for Fluorescence-Guided Surgery in Pancreatic Cancer, Evie Ehrhorn

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Chlamydia trachomatis Modulation of Epithelial Innate Immunity, Francis L. Fontanilla

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Application of a Novel Immunoassay to Understand Population-Level Humoral Immunity Against Emerging SARS-CoV-2 Variants, Dylan S. George

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Erythropoietic Functions of Sterile Alpha Motif Domain Containing Protein-1 (SAMD1) Transcription Factor, Samantha Gomez

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Measuring the Influence of Physical Activity and Fitness on Development of Cognition, Brain Structure, and Brain Function in Periadolescent Children, Abi Heller-Wight

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Bovine Colostrum Extracellular Vesicles as Nutraceuticals or Pharmaceuticals for Parkinson’s Disease, Dawson E. Hollingsworth

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Impact of Social and Geospatial Factors on Pediatric Cancer Survival: An Analysis of State Cancer Registry Data, Emma Hymel

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Comparing Two Variations of the High Probability Instructional Sequence in Increasing Acceptance of Novel Foods among Children with Food Selectivity, Angelica Ibarra Donahue

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Antagonistic Regulation of MCL-1 Protein Stability by PR55α- and PR61α-Directed PP2A in Pancreatic Cancer, Sharon Krithi Jegadish

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Pathogenetic Insight in the Molecularly Defined Subtype of Peripheral T-cell Lymphoma, Not Otherwise Specified, Dylan T. Jochum

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Biophysical Models of West Nile Virus Transmission in Culex pipiens, Hunter Michael Jones

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Financial Hardship and Quality of Life among Caregivers of Children with Cancer in Nebraska, Josiane Kabayundo

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Fine-Scale Chromatin Compartments Reveal by CRUSH: Development and Functional Insights into Genome Organization, Achyuth Kalluchi

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Coxiella burnetii Modulates the Host Protein TFEB to Promote Infection, Brigham Killips

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Exploring Cancer Stem Cell Dependencies for Therapeutic Interventions in Pancreatic Cancer, Nivedeta Krishna Kumar

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Making HPV Visible: HPV-Related Cancer Prevention And Detection Among Sexual And Gender Diverse Men, Andy Lim

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Multilayer Environmental Exposures and Coccidioidomycosis: From Effect Estimation to Predictive Modelling, Qianqian Li

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Effects of Amyloid Beta on Visual System Structure and Function, Shaylah McCool

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An Examination of Trauma-Informed Care Organizational Readiness and Employee Outcomes in Child-Serving Organizations, Maria S. Mickles

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Identifying Reliably Expressed Neoantigens Presented on Major Histocompatibility Complex Class I in Pancreatic Adenocarcinoma, William R. Miklavcic

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Measuring What Matters: A Cross-Sectional Assessment of Disease-Specific Self- and Proxy-Reported Quality of Life in Pediatric Intestinal Failure, Marie L. Neumann

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Asthma in Agriculture and Powered Respirator Communication Challenges: Implications for Occupational Respiratory Protection, Ikenna Orji

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Elucidating the Mechanism of CBFB::MYH11 after Disease Onset in Inversion(16) Leukemia, Sipra Panda

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Pancreatic Cancer Subtype Prediction Via Advanced Machine Learning Approaches, Nicholas B. Peterson

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Does Living in the Ruff Part of Town Matter? The Impact of Neighborhood Disadvantage on Human and Pet Health, Christopher Pierson

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Reconceptualizing Rurality in Health Research: Implications for Intervention Design, Elizabeth Reisher

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Targeting ERRα in the PGC-1β Signaling Cascade in Aggressive Colorectal Cancer, Kamryn A. Reynolds

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Mechanistic Insights into Anemia Recovery: The Samd14-PI3P Regulatory Axis Balances Autophagy, Pooja Roy

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Hybrid Fibrous Aerogels for Regenerative Medicine, Hemostasis, and Minimally Invasive Cancer Diagnosis, S M Shatil Shahriar

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Neutrophil–Pancreatic Cancer Interplay Defines a Microenvironmental Axis that Sustains Neutrophil Survival and Pro-tumorigenic Reprogramming, Reegan Sturgeon

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Development of Ultra-Long-Acting Treatments for Opioid Overdose and Fibrosis, Ashrafi Sultana

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Community Engagement Competency of Critical Access Hospital Chief Executive Officers in Nebraska, Jessica B. Tschirren

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Chemical Genetic Screening and Mechanistic Validation of HBC-8: A Heterobifunctional Compound with MAP3K1 and CRBN-Dependent Anti-Cancer Effects, Lelisse T. Umeta

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Glycoproteome and GlycoRNA Reprogramming in Pancreatic Cancer Progression and Metastasis, Venkatesh Varadharaj

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Understanding the Mechanism of Action of NB Compound Small Molecule Inhibitors in High-Grade Serous Ovarian Carcinoma, Makenzie Vorderbruggen

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PDAC Models with KRASG12R Show Elevated MHC Class I Expression, Elina Lynge Wagner

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Development of Small-Molecule Therapeutics Targeting Neurodegenerative Diseases and Oncology, Thomas Webster

Theses/Dissertations from 2025

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Targeting SGPP1 in Pancreatic Cancer: Valproic Acid as a Potential Therapeutic via HDAC Inhibition and S1P Pathway Modulation, Hamed Abbasi

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Understanding Agricultural Injury Burden and Prevention: Economic Costs, Military Service Factors, and Safety Training Challenges in the United States, Suraj Adhikari

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Advancing Drug Development through Translational DMPK and Model-Informed Pharmacokinetic Approaches, Nusrat Ahmed

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Beyond the Bruise: Understanding Injury Risk Factors Among Livestock Workers in Cattle Feedyards and Animal Handling Farms and Ranches, Rishad Ahmed

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Relationship Between Maternal Plasma Retinol and Provitamin A Carotenoids with Fetal and Infant Kidney Development, Anum Akbar

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Colostrum Extracellular Vesicle are Neuroprotective in the MPTP Intoxicated Mouse Model of Parkinson's Disease, Samia Akter

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From Vector to Consequence: Integrating Vector Surveillance, Environmental Drivers, and Public Health Impact into Lyme Disease Risk Management, Kathleen E. Angell

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Navigating the Divide: COVID-19 Vaccine Access, Uptake, and Persistent Vaccine Refusal in Nebraska, Julia Bai

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Posterior Anatomic Limit for Mandibular Molar Distalization in Subjects with Different Growth Patterns, Genders, and Growth Status, Rehana Bashir

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Functional Importance of Pax5 and NrCAM in Highly Aggressive AR-Independent Prostate Cancer, Sreyashi Bhattacharya

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Oncomucin-Mediated Stromal Remodeling in Pancreatic Cancer, Namita Bhyravbhatla

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A Novel Approach for Understanding the Role of Bone Remodeling in Early Structural Knee Osteoarthritis, Reece Blay

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Mechanistic Insight of Neuropilin-2 Expression during the Progression of Prostate Cancer, Sanika Bodas

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Development and Evaluation of the Cystiene Cathepsin Trapping Approach Incorporated in NTSR1- and FAP-Targeted Radiotherapeutics, Katherine Brake

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Immunosuppression and Epigenetic Therapy: Amyloid Precursor-Like Protein 2-Mediated Macrophage Dynamics and Histone Deacetylase Inhibition in Neuroblastoma, Gabrielle L. Brumfield

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Neuroplasticity in Motion: Exploring Neural Oscillatory Activity and Physical Therapy Interventions in Adolescents and Adults with Cerebral Palsy, Morgan T. Busboom-Matulka

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MUC16 and COL7A1 in ECM Remodeling in Lung Adenocarcinoma Metastasis, Daniela Castillo Daura

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Investigating the Effects of Transcription Factor Binding and Genetic Variants in the Striatum of Post-Mortem Cohorts with Opioid Use Disorder, Rajashree Chakraborty

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Evaluating Current Practices in Operative Nontechnical Skills Training and Feedback in General Surgery Residency: A Mixed Methods Approach, Madeline Cloonan

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Coordinating Connections: A Mixed-Methods Exploration of Relational Coordination and Interprofessional Team Development with Health Professions Students and Survivors of Stroke, Teresa Marie Cochran

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Evaluating Clinical Competency in Undergraduate Nursing Students: A Mixed Methods Study, Emily C. Coffey

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Prebiotics to Augment the Gut Microbiome for Patients with Lymphoma or Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation: The Primal Trial, Christopher R. D'Angelo

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Variable Selection and Prediction Using Machine Learning Models in High-Dimensional Data, Apu Chandra Das

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Evaluating Joint Control Teaching Procedures for Teaching Yes-No Responding with Tact and Intraverbal Questions for Children with Autism, Desiree J. Dawson

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The Splicing Factor PTBP1 Interacts with RUNX1 and is Required for Leukemia Cell Survival, Arjun Dhir

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The Design, Synthesis and Biological Evaluation of Novel 17β-Hydroxysteroid Dehydrogenase Modulators, Louise F. Dow

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BET Protein Inhibition Relieves Myeloid-Derived Suppressor Cell-mediated Immune Suppression in Chronic Lymphocytic Leukemia, Erin M. Drengler

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Neurodegenerative Disease Mechanisms: Mitochondrial Impairment, Tau Aggregation, and Neuroinflammation as Central Drivers of Disease Progression, Luis D. Estrella

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Regulation of Chromatin Remodeling by the Post-HSA Domain of BRG1, a Subunit the BAF ATP-Dependent Chromatin Remodeling Complex, Min Sze Ewe

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Exposures, Protections, and Barriers: Advancing Understanding of Agricultural Worker Health, Alexandra A. Farfalla

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Unmasking B7-H3: A Spontaneous Small-Cell Lung Cancer Model Reveals its Dual Role in Tumor Progression and Immune Modulation, Mahek Fatima

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Understanding Stakeholder Perspectives, Medical Student Metacognition and Reflections on Learning Order Entry in the Electronic Health Record, Abbey L. Fingeret

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Schistosoma haematobium Infection in Ethiopian Children: Evaluating Praziquantel Efficacy, Nutritional Effects, and Diagnosis Using FlukeCatcher, Louis Fok

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Phosphorylation Modulates the Structure and Function of Replication Protein A, Valerie J. Fousek-Schuller

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Multi-Modal MRI for the Pre-Clinical Evaluation of HIV-Linked Changes in the Central Nervous System, Gabriel Gauthier

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A Comparison of Resurgence Following DRA and DRO, Alysa Georgopoulos

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Role of NADPH Oxidase 4 in Murine Cancer-Associated Fibroblast, Faith M. Gomez

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Navigating Nutrition Between Cultures: A Mixed Methods Study of Dietary Acculturation and Generational Status in Mexican-American Populations, Roger Gonzales

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A Comparison of Tenecteplase to Alteplase for Treatment of Acute Ischemic Stroke Using Epic Cosmos Database, Marco Gonzalez Castellon

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Role of Stabilin-1 Expressing Macrophages in Colorectal Liver Metastasis, Jampa L. Gurung

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Targeting Oxidative and Nitrosative Stress: The Role of Omega-3 Derived RvD2 and NRF2 Signaling in Hypertensive-Affected Placenta, Taija Hahka

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Cysteine-Mediated Redox Balance in Staphylococcus aureus, Abigail Hall

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Investigate the Role of TGFβ3 in Regulating IRF6 and ΔNp63 in Periderm Desquamation, Nam Ha

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Integrating Artificial Intelligence and Machine Learning with Causal Inference for Early Detection & Management of Cardiac Rejection, Roman G. Haynatzki

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The Effects of Arbitrary Reinforcers on DRO Efficiency, Reinstatement, and Reacquisition, Zeinab Hedroj

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Temporal Patterns of Ectopic Pregnancy: Using the Electronic Health Record to Illuminate a Dark Corner in Women's Health, Kirsten Hepburn

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An Extension of a Break-to-Choice Intervention with Isolated Contingency Tests for Children with Multiply Maintained Challenging Behavior, McKenna E. Herbek

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Microbiome Compositional State and Its Relation to Gut Dysbiosis in the Common Marmoset, Jordan B. Hernandez

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Presence and Performance: A Cross-Campus Analysis of Academic Performance and Course Evaluations Through the Lens of the Community of Inquiry, Shaun Horak

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Kinase Suppressor of Ras 2 Regulates Energy Balance and Tumor Initiation, Dianna H. Huisman

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Navigating Lipid Nanoparticle Design: From Microfluidic Optimization for RNA Delivery in Pancreatic Cancer to Extended-release Formulations for HIV-1 Therapy., Farhana Islam

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Optimal Two-Stage Phase II Bayesian Design, Yuanyuan Ji