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Theses/Dissertations from 2026

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Novel Approaches for Environmental Surveillance of Viral Aerosols: Detection, Characterization, and Analysis, Daniel Ackerman

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Model-Informed Drug Development for Pediatric Group 3 Medulloblastoma, Prachi Agrawal

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Evaluating FOXM1 Hydrophobic Tag Degraders in High-Grade Serous Ovarian Cancer Cells, Tania Aguilera Pineda

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Engineering Approaches to Promote Peripheral Nerve Injury and Denervated Muscle Regeneration, Olawale Alimi

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Utilization and Survival Association of Immunotherapy in Pediatric and Adult Sarcoma Patients Who Did Not Have Surgery: A National Cancer Database Analysis, Jenna Allison

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Design, Synthesis, and Evaluation of Putative B7-H3 Inhibitors for Group 3 Medulloblastoma, Hamdan Alrefaei

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Assessing Infection Control Practices Among EMS Providers in Prehospital Settings: A Comprehensive Study Examining Compliance and Barriers, Abdulrahman Alsaleem

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Promoting Social Communicative Gestures by Minimally Verbal Children with Autism, Rebecca J. Barall

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Replication and Extension of KRAS-Associated Gene Expression Signatures in Lung Adenocarcinoma: A Cox Proportional Hazards Analysis of Mutation Status, Gene Expression, Multi-Gene Mutation Count, and RAS de Novo Signature, Camryn Berry

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Unraveling the Accelerated HIV-1 and Alzheimer’s Disease Neuropathology in Humanized APP Knock-In Mice, Shaurav Bhattarai

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The Role of ORAI1 Store-Operated Calcium Channel in Mitotic Cell Shape, Azize Cerci

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KSR1 Mediates SCLC Tumor Initiation and Cisplatin Resistance, Deepan Chatterjee

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Promoter G-Quadruplexes Scaffold Apurinic/Apyrimidinic Endonuclease 1 (APE1) to Promote Oncogene Expression in Triple-Negative Breast Cancer, Yingling Chen

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Development of Water-Soluble Nanofibrous Poly(Vinyl Alcohol) Collectors for Bioaerosol Sampling and Environmental Surface Microbial Detection, Kevin Crown

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Therapeutic Strategies in Glioblastoma and Acute Kidney Injury: Androgen Receptor-Directed Therapy for High-Grade Glioma and Nanoparticle-Based Therapeutic Strategies for Cisplatin-Induced Nephrotoxicity, Ashish Das

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Molecular and Structural Determinants of Ovarian Aging, Dipanwita Das

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The Role of Neural Oscillations as Biomarkers of Epilepsy: A Multimodal Computational Approach, Srijita Das

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Optimization of the Near-Infrared Fluorescence Probe: HuAR9.6-IRDye800 for Fluorescence-Guided Surgery in Pancreatic Cancer, Evie Ehrhorn

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Analytical Approaches for Enhancing fMRI Brain Mapping Accuracy in Individuals, David G. Ellis

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Impacts of Standardized Documentation and Workflow on Cancer Data Quality and Accessibility in the EHR, Andrea L. Englund

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Chlamydia trachomatis Modulation of Epithelial Innate Immunity, Francis L. Fontanilla

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Actin at the Early Endosome: Roles in Cargo Sorting and Endosome Fission, Devin Frisby

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Application of a Novel Immunoassay to Understand Population-Level Humoral Immunity Against Emerging SARS-CoV-2 Variants, Dylan S. George

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Targeted Combination Nanomedicine to Overcome Oncogenic, Metabolic, and Microenvironmental Resistance in Pancreatic Ductal Adenocarcinoma, Yashwardhan Ghanwatkar

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Erythropoietic Functions of Sterile Alpha Motif Domain Containing Protein-1 (SAMD1) Transcription Factor, Samantha Gomez

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Sleep Disturbances Associated with Amyloid Pathology in Alzheimer’s Disease, Siyin Guo

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Targeted Nanomedicine Strategies for Enhanced Drug Delivery and Therapeutic Efficacy in Medulloblastoma, Aditya Gupta

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Measuring the Influence of Physical Activity and Fitness on Development of Cognition, Brain Structure, and Brain Function in Periadolescent Children, Abi Heller-Wight

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Mucin1 in Extracellular Vesicle Biology and Pancreatic Cancer: Mechanistic Roles and Disease Relevance, Kristine V. Hoagstrom

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Bovine Colostrum Extracellular Vesicles as Nutraceuticals or Pharmaceuticals for Parkinson’s Disease, Dawson E. Hollingsworth

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Impact of Social and Geospatial Factors on Pediatric Cancer Survival: An Analysis of State Cancer Registry Data, Emma Hymel

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Comparing Two Variations of the High Probability Instructional Sequence in Increasing Acceptance of Novel Foods among Children with Food Selectivity, Angelica Ibarra Donahue

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Spatial Transcriptomic Evaluation of Healing Periodontal Tissue Post Extraction, Greg Ingalsbe

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Antagonistic Regulation of MCL-1 Protein Stability by PR55α- and PR61α-Directed PP2A in Pancreatic Cancer, Sharon Krithi Jegadish

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Pathogenetic Insight in the Molecularly Defined Subtype of Peripheral T-cell Lymphoma, Not Otherwise Specified, Dylan T. Jochum

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Biophysical Models of West Nile Virus Transmission in Culex pipiens, Hunter Michael Jones

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DHX40 Regulates Sensitivity of Mismatch Repair Proficient Cells to DNA-Protein Crosslink-Inducing Agents, Vaishnavi Sunil Joshi

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Financial Hardship and Quality of Life among Caregivers of Children with Cancer in Nebraska, Josiane Kabayundo

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Fine-Scale Chromatin Compartments Reveal by CRUSH: Development and Functional Insights into Genome Organization, Achyuth Kalluchi

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An Exploratory Analysis of a Laboratory Model for Mitigating Caregiver Fidelity Errors by Teaching an Alternative Response, Jasmeen Kaur

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Coxiella burnetii Modulates the Host Protein TFEB to Promote Infection, Brigham Killips

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Exploring Cancer Stem Cell Dependencies for Therapeutic Interventions in Pancreatic Cancer, Nivedeta Krishna Kumar

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Making HPV Visible: HPV-Related Cancer Prevention And Detection Among Sexual And Gender Diverse Men, Andy Lim

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Multilayer Environmental Exposures and Coccidioidomycosis: From Effect Estimation to Predictive Modelling, Qianqian Li

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Understanding Moral Distress in New Graduate Nurses: Evidence to Promote Professional Nursing Practice, Lauren A. Loyd

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Advancing Maternal Health Equity in Nebraska: Examining Prenatal Care Access Disparities, Policy Context, and Doula Integration as a Complementary Solution, Marlette Grace Dulcinee Mabiala-Maye

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Effects of Amyloid Beta on Visual System Structure and Function, Shaylah McCool

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An Examination of Trauma-Informed Care Organizational Readiness and Employee Outcomes in Child-Serving Organizations, Maria S. Mickles

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Identifying Reliably Expressed Neoantigens Presented on Major Histocompatibility Complex Class I in Pancreatic Adenocarcinoma, William R. Miklavcic

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Multi-Target CNS Drug Discovery Through Synthetic and SAR-Driven Optimization, Sumaiya Nahid

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Toward Precision Medicine in Bronchiolitis: Clinical Phenotypes, Airway Inflammation, and Nasopharyngeal Proteomic Signatures, Kari Neemann

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Measuring What Matters: A Cross-Sectional Assessment of Disease-Specific Self- and Proxy-Reported Quality of Life in Pediatric Intestinal Failure, Marie L. Neumann

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Multi-Mechanistic Treatment Approaches for Hepatitis B and Malaria, Mojisola O. Ogunnaike

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HIV Tat-Mediated Astrocytic PANoptosis Involves Neuroinflammation, Elizabeth Kehinde Oladipo

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Quantitative Methods for Assessing Subtle Syndesmotic Injury: Enhancing Diagnostics with Weightbearing Computed Tomography, Kareem Omran

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Asthma in Agriculture and Powered Respirator Communication Challenges: Implications for Occupational Respiratory Protection, Ikenna Orji

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Elucidating the Mechanism of CBFB::MYH11 after Disease Onset in Inversion(16) Leukemia, Sipra Panda

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Pancreatic Cancer Subtype Prediction Via Advanced Machine Learning Approaches, Nicholas B. Peterson

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Does Living in the Ruff Part of Town Matter? The Impact of Neighborhood Disadvantage on Human and Pet Health, Christopher Pierson

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Extracellular Vesicle and Nanoparticle - Mediated Crosstalk Between Skeletal Muscle and the Heart: A Role for Antioxidant Proteins and Nrf2, Sarah Pribil Pardun

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Through the Looking Glass: A Neurodevelopmental Perspective on Alzheimer's Disease-Vulnerable Brain and Cognitive Systems, Meghan Ramirez

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Replication and Extension of "Validation of a Histology-Independent Prognostic Gene Signature for Early-Stage Non-Small-Cell Lung Cancer Including Stage IA Patients", Md Saif Uddin Rashed

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Reconceptualizing Rurality in Health Research: Implications for Intervention Design, Elizabeth Reisher

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Targeting ERRα in the PGC-1β Signaling Cascade in Aggressive Colorectal Cancer, Kamryn A. Reynolds

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Mechanistic Insights into Anemia Recovery: The Samd14-PI3P Regulatory Axis Balances Autophagy, Pooja Roy

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EHR-Embedded Integrated Care Pathways in Pediatric Care: Usability, Clinical Outcomes, and Cost Evaluation, Makayla Schissel

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Hybrid Fibrous Aerogels for Regenerative Medicine, Hemostasis, and Minimally Invasive Cancer Diagnosis, S M Shatil Shahriar

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Assessing the Impact of Medical Escape Rooms on Learner Engagement, Zachary P. Slocum

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Neutrophil–Pancreatic Cancer Interplay Defines a Microenvironmental Axis that Sustains Neutrophil Survival and Pro-tumorigenic Reprogramming, Reegan Sturgeon

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Development of Ultra-Long-Acting Treatments for Opioid Overdose and Fibrosis, Ashrafi Sultana

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Community Engagement Competency of Critical Access Hospital Chief Executive Officers in Nebraska, Jessica B. Tschirren

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Chemical Genetic Screening and Mechanistic Validation of HBC-8: A Heterobifunctional Compound with MAP3K1 and CRBN-Dependent Anti-Cancer Effects, Lelisse T. Umeta

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Glycoproteome and GlycoRNA Reprogramming in Pancreatic Cancer Progression and Metastasis, Venkatesh Varadharaj

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Understanding the Mechanism of Action of NB Compound Small Molecule Inhibitors in High-Grade Serous Ovarian Carcinoma, Makenzie Vorderbruggen

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PDAC Models with KRASG12R Show Elevated MHC Class I Expression, Elina Lynge Wagner

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Development of Small-Molecule Therapeutics Targeting Neurodegenerative Diseases and Oncology, Thomas Webster

Theses/Dissertations from 2025

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Targeting SGPP1 in Pancreatic Cancer: Valproic Acid as a Potential Therapeutic via HDAC Inhibition and S1P Pathway Modulation, Hamed Abbasi

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Understanding Agricultural Injury Burden and Prevention: Economic Costs, Military Service Factors, and Safety Training Challenges in the United States, Suraj Adhikari

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Advancing Drug Development through Translational DMPK and Model-Informed Pharmacokinetic Approaches, Nusrat Ahmed

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Beyond the Bruise: Understanding Injury Risk Factors Among Livestock Workers in Cattle Feedyards and Animal Handling Farms and Ranches, Rishad Ahmed

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Relationship Between Maternal Plasma Retinol and Provitamin A Carotenoids with Fetal and Infant Kidney Development, Anum Akbar

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Colostrum Extracellular Vesicle are Neuroprotective in the MPTP Intoxicated Mouse Model of Parkinson's Disease, Samia Akter

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From Vector to Consequence: Integrating Vector Surveillance, Environmental Drivers, and Public Health Impact into Lyme Disease Risk Management, Kathleen E. Angell

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Navigating the Divide: COVID-19 Vaccine Access, Uptake, and Persistent Vaccine Refusal in Nebraska, Julia Bai

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Posterior Anatomic Limit for Mandibular Molar Distalization in Subjects with Different Growth Patterns, Genders, and Growth Status, Rehana Bashir

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Functional Importance of Pax5 and NrCAM in Highly Aggressive AR-Independent Prostate Cancer, Sreyashi Bhattacharya

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Oncomucin-Mediated Stromal Remodeling in Pancreatic Cancer, Namita Bhyravbhatla

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A Novel Approach for Understanding the Role of Bone Remodeling in Early Structural Knee Osteoarthritis, Reece Blay

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Mechanistic Insight of Neuropilin-2 Expression during the Progression of Prostate Cancer, Sanika Bodas

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Development and Evaluation of the Cystiene Cathepsin Trapping Approach Incorporated in NTSR1- and FAP-Targeted Radiotherapeutics, Katherine Brake

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Immunosuppression and Epigenetic Therapy: Amyloid Precursor-Like Protein 2-Mediated Macrophage Dynamics and Histone Deacetylase Inhibition in Neuroblastoma, Gabrielle L. Brumfield

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Neuroplasticity in Motion: Exploring Neural Oscillatory Activity and Physical Therapy Interventions in Adolescents and Adults with Cerebral Palsy, Morgan T. Busboom-Matulka

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MUC16 and COL7A1 in ECM Remodeling in Lung Adenocarcinoma Metastasis, Daniela Castillo Daura

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Investigating the Effects of Transcription Factor Binding and Genetic Variants in the Striatum of Post-Mortem Cohorts with Opioid Use Disorder, Rajashree Chakraborty

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Evaluating Current Practices in Operative Nontechnical Skills Training and Feedback in General Surgery Residency: A Mixed Methods Approach, Madeline Cloonan

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Coordinating Connections: A Mixed-Methods Exploration of Relational Coordination and Interprofessional Team Development with Health Professions Students and Survivors of Stroke, Teresa Marie Cochran

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Evaluating Clinical Competency in Undergraduate Nursing Students: A Mixed Methods Study, Emily C. Coffey

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Prebiotics to Augment the Gut Microbiome for Patients with Lymphoma or Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation: The Primal Trial, Christopher R. D'Angelo

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Variable Selection and Prediction Using Machine Learning Models in High-Dimensional Data, Apu Chandra Das

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Evaluating Joint Control Teaching Procedures for Teaching Yes-No Responding with Tact and Intraverbal Questions for Children with Autism, Desiree J. Dawson