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Theses/Dissertations from 2021

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Design, Synthesis and Antineoplastic Evaluation of a Variety of Small Molecule Scaffolds, Bader Huwaimel

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The Rotator Cuff Tendon-to-Bone Interface: Maturation, Aging, and 3D Bioprinting for Regeneration, Xiping Jiang

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Understanding the Impact of Chlamydia Trachomatis Infection on Host Vesicular Trafficking, Lisa M. Jorgenson

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A PKCα-Mediated Growth Suppressive MEK-ERK Signaling Axis in Intestinal Epithelial Cells, Navneet Kaur

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Reach, Effectiveness, Adoption, and Maintenance of Mobile Electronic Clinical Decision Support Tools Deployed as Part of National Quality Improvement Projects, Ellen K. Kerns

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Utilizing Proteolysis-Targeting Chimeras to Target the Transcriptional Cyclin-Dependent Kinases 9 and 12, Hannah King

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Nuclear Receptor Coactivator 3 in Endoplasmic Reticulum Stress and Stress Granule Dynamics in Pancreatic Cancer, Andrew Kisling

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The Effect of Locally Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients, Lauren Krell

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Development of Once-A-Year Injectable Formulation of Cabotegravir for Prevention and Treatment of HIV Infection, Tanmay Abhay Kulkarni

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Molecular Mechanisms of Aberrant Protein Glycosylation in Pancreatic Cancer Stemness and Metastasis, Frank Leon

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Multimodal Neuroimaging of HIV and Aging, Brandon Lew

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Clinical Consequences and Determinants of False Positive Blood Cultures in Adult Hospitalized Patients, Sidra Liaquat

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Predicting Reinforcers to Increase Physical Activity in Young Children with Obesity using the Six-Minute Walk Test, Jordan D. Lill

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Urinary Bile Acid Indices as Prognostic Biomarkers for the Complications of Liver Diseases, Wenkuan Li

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Delineation of New Mechanisms of DNA Damage Responses and Repair, YANQIU LI

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Insights into Cutaneous Squamous Cell Carcinoma Pathogenesis and Metastasis Using a Bedside-to-Bench Approach, Marissa Lobl

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Gene Expression Profiling of MAPK Pathway Inhibitor Resistance in Cutaneous Melanoma: Can Bioinformatics Be Used to Select Better Melanoma Cell Lines?, Stephen Luebker

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Is the Walking Pattern Similar Between Slope Walking and Obstacle Negotiation?, Jiani Lu

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Utilization of a Cell Mediated Immunity Assay to Adjust Immunosuppression Following Heart Transplantation, Scott Lundgren

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Humanized Mice for Brain Infection of Emerging Viruses, Edward Makarov

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Marinopyrrole Derivatives as Putative Antiparasitic Molecules Promoting Initiation of Programmed Cell Death in Toxoplasma gondii, Matthew C. Martens

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Engineering Advanced Micro and Nanofiber Materials for Biomedical Applications, Alec D. McCarthy

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Evaluating Self-Management of Adults with Multiple Chronic Conditions Residing in Rural Communities: A Descriptive Cross-Sectional Study, Jessica J. Miller

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Design, Synthesis and Evaluation of Novel Inhibitors of Type 5 and 10 17β-Hydroxysteroid Dehydrogenases, Ahmed Morsy

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Health Service Utilization and Expenditure in Cardio-Metabolic Conditions in the United States Adults, Kavita Mosalpuria

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The Effect of Orthodontic Treatment With Extraction on The Upper Airway Dimensions and Three-Dimensional Morphology: A Retrospective Study Using Cone-Beam Computed Tomography Technique, Ehsan Mostaghni

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Development of Macromolecular Prodrug of Sinomenine for the Treatment of Rheumatoid Arthritis, Roshni Mukundan

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Role Of Endocytic Machinery Regulators in EGFR Traffic and Viral Entry, Insha Mushtaq

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Neurocognitive impairment in people living with human immunodeficiency virus (HIV): Risk factors and mortality, Zaeema Naveed

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In utero and Postnatal Oxycodone Exposure: Implications for Intergenerational Effects, Katherine E. Odegaard

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Development of a MUC16-Targeted Near-Infrared Antibody Probe for Fluorescence-Guided Surgery of Pancreatic Cancer, Madeline T. Olson

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Immunological Factors Associated with SIV/ SHIV Persistence in Diverse Tissue Niches, Omalla A. Olwenyi

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StrainIQ: An n-gram-based Method to Identify and Quantify Microbial Communities in Metagenomic Samples, Sanjit Pandey

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The Role of Micrornas in the Pathophysiology of Neonatal Hypoxic-ischemic Brain Injury, Eric S. Peeples

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USP11 and USP7 Deubiquitinases Regulate SPRTN Auto-proteolysis and SPRTN-mediated DNA-protein Crosslink Repair, Megan C. Perry

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FGFR4 glycosylation and processing in cholangiocarcinoma promote cancer signaling, Andrew J. Phillips

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Indices of Happiness and Unhappiness During Treatment of Pediatric Feeding Disorders, Laura Elizabeth Phipps

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Investigation of Environmental Lead Exposures in Children at A Midwestern City with Superfund Site, Zijian Qin

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Probing the role of astrocytes in the pathology of fragile X syndrome with human stem cells, Baiyan Ren

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Characterization of Di-Aryl Urea Compounds Against Acute and Chronic Toxoplasma Gondii, Austin Sanford

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Mechanism of the Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+ and its Nanoformulation on Blood Pressure Regulation, Sarah L. Schlichte

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Characterization of Aerosols Produced by Common Orthodontic Procedures, Anna R. Schoettger

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Proof of Concept: The Use of Renal Biomarkers in Critically Ill Pediatric Patients for Therapeutic Drug Monitoring, Christopher Lee Shaffer

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Design and Synthesis of Small Molecular probes for CNS and Kidney Disorders, Swagat H. Sharma

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Phase Duration and Resurgence, Sean Smith

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Integrative Analysis of Multi-omics Kinome Data and Virtual Screening of Identified Targets with Pan-Cancer Application, Siddesh Southekal

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Neural Oscillatory Activity Serving Sensorimotor Control is Regulated by the Mitochondrial Redox Environment in Health and Disease, Rachel Spooner

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Structural and Inhibitory Studies of Enzymes Essential for Cell Wall and Ergothioniene Biosynthesis in Mycobacterium Tuberculosis, Thanuja D. Sudasinghe

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Development of Polymeric CXCR4 Targeting Carriers for siRNA Delivery to Treat Acute Kidney Injury, Weimin Tang

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Impact of Prescription Drug Monitoring Program on Drug Misuse and Drug-related Fatal Vehicle Crashes, Moosa Tatar

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Mucin and Splice Variant Profiles of Pancreatic Adenocarcinoma Predict Patient Survival and Subtyping, Christopher M. Thompson

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Glad To Be Out. I Was Running Out of Womb: A Study of Omega-6 and Omega-3 Fatty Acid Metabolites at Delivery and their Relationship to Infant Growth, Prematurity, and Admission to the Neonatal Intensive Care Unit, Maranda Thompson

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The Neurological Abnormalities of the Brain and Spinal Cord in Individuals with Cerebral Palsy, Michael Trevarrow

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From Pipeline to Health Equity: A Case Study of Health Profession Pipeline Students, Sonja F. Tutsch

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Using Prompt Delay and Instructive Feedback to Teach Pretend Play Skills to Children with Autism Spectrum Disorder, Gabriella R. Van Den Elzen

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Post-Transplant Hepatic Graft Fibrosis in Pediatric Liver-Inclusive Transplant Recipients, Hanh D. Vo

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Dynamics of Protein-DNA Interactions Characterized by Atomic Force Microscopy, Yaqing Wang

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The effect of obstacle intervals on foot integrated pressure and obstacle negotiation strategy, Zhuo Wang

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Use of Telehealth in Home-based End-of-Life Care for Children in Rural Regions, Meaghann S. Weaver

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The Effect of Polyunsaturated and Saturated Fatty Acids on Seizure Presence and Severity in a Cohort of Subjects in an Epilepsy Monitoring Unit, Jana K. Wells

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Superoxide and Pulmonary Hypertension, Tammy Wichman

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Cardio-Renal Syndrome Type 2: The Role of Cardiac Spinal Afferent Reflex, Zhiqiu Xia

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Delivery of SiRNA with Drugs Targeting Polyamine Metabolism as Combinational Cancer Treatment, Ao Yu

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Molecular Pathogenesis of a Novel Subgroup of Peripheral T-cell Lymphomas, Jiayu Yu

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The Role of VGLL4 and MARK2-HDAC axis in Mitosis and Cancer, Yongji Zeng

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Adaptation of Human Locomotion and Unilateral Limb Loading During Different Inclination Treadmill Walking, Yuhang Zhang

Theses/Dissertations from 2020

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Bayesian Modeling for Longitudinal Count Data: Applications in Biomedical Research, Morshed Alam

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Urinary Bile Acid Indices as Diagnostic and Prognosic Biomarkers for Liver Diseases, Jawaher Alamoudi

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Exploring Paramedic Students’ Level of Preparedness for Disaster Response in Hajj 2019, Nawaf Albaqami

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Development of an LC-ESI-MS/MS method for determination of a novel Pyrrolomycin (MP-1) and application to pre-clinical ADME studies, Wafaa N. Aldhafiri

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Planning and Facilitating the Training of Emergency Medical Services on the Safe Transport of Patients with Highly Infectious Diseases, Mohammed Alhallaf

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Inflammatory Cytokine Expression of Immune Cells on Exposure to Invisalign® Material: An In Vitro Pilot Study, Alaina M. Allen

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Delivery for Hydrophobic Drugs for Treating Pancreatic Cancer, Saud Almawash

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Characterization of Novel Animal Models for Parkinson’s Disease, Mohannad Almikhlafi

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Polymeric Drug Delivery Systems for Cancer Therapy and Radionuclide Decorporation, Sameer A. Alshehri

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Impact of Immunotherapy on the Survival of Pancreatic Adenocarcinoma Patients: An Analysis of the National Cancer Database, Saber A. Amin

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Effect of Nanofiller Coating and Loading on Facial Elastomer Physical Properties, Rahmi K. Aulia

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Deciphering the Catalytic Mechanism of Human Manganese Superoxide Dismutase, Jahaun Azadmanesh

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Fundamental differences in the B cell locus, V(D)J repertoire, and Marburg virus epitope recognition of the Egyptian rousette bat that may allow for asymptomatic presentation, Maggie Linn Bartlett

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Integrating Geriatric Assessment and Genetic Profiling to Personalize Therapy Selection in Older Adults with Acute Myeloid, Vijaya R. Bhatt

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Boundary Conditions of Observational Learning in Children with Autism Spectrum Disorders, Andrew Blowers

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DNA Polymerase ε: Replication Error Prevention and Consequences of a Cancer-Associated Mutation, Chelsea R. Bulock

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The Role of the CXCR3 Signaling Axes in Pancreatic Ductal Adenocarcinoma, Andrew C. Cannon

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Novel Detection and Treatment Strategies for Pancreatic Ductal Adenocarcinoma, Joseph Carmicheal

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Ocular, Neural, and Cellular Biodistribution of Multifunctional Antioxidants, Damian Daszynski

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Cooperativity of CCNE1 and FOXM1 in High-Grade Serous Ovarian Cancer, Lucy Elge

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Comparative Analysis of National Emergency Management Charters: A Pilot Study Towards Achieving a Standardized Global Emergency Management Framework, Wael ElRayes

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Novel regulatory roles of endocytic membrane trafficking proteins in mitochondrial homeostasis, Trey Farmer

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Effects of Liquid Viscosity and Food Texture on Swallowing Sounds, Chun Feng

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Flavonoid and Cannabidiol Neural Glyoxalase Pathway Enhancement Against Aging and Alzheimer’s Disease, Joel R. Frandsen

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Characterizing the critical role of metabolic and redox homeostasis in colorectal cancer, Danielle Frodyma

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The Evolving Management of Aortic Valve Disease: Trends in the Utilization and Cost of SAVR, TAVR, and Medical Therapy, Andrew Goldsweig

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Leveraging Aqueous Humor Dynamics and Ocular Biometrics for Improving Therapeutic Outcomes in Glaucoma, Vikas Gulati

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An Evaluation of a Renewal-Mitigation Procedure for Inappropriate Mealtime Behavior, Sarah D. Haney

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Development of CXCR4-inhibiting RNA delivery vectors for the treatment of metastatic pancreatic cancer, Yu Hang

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Beyond the eye: The neural signature of cerebral visual processing in children with cerebral palsy, Jacy R. Hannan

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Comprehensive analysis of chromosome 14q32 deletions in chronic lymphocytic leukemia, Rachel A. Harris

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Multiquantal Glutamate Release from Rod Photoreceptors, Cassandra L. Hays

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Multistrain HIV-1 Elimination: A CRISPR-Cas9 and Theranostics-based Approach, Jonathan Herskovitz

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The Neural Oscillatory Dynamics Underlying Motor and Cognitive Abilities in Children And Adults with Cerebral Palsy, Rashelle M. Hoffman