Theses/Dissertations from 2025
Targeting SGPP1 in Pancreatic Cancer: Valproic Acid as a Potential Therapeutic via HDAC Inhibition and S1P Pathway Modulation, Hamed Abbasi
Advancing Drug Development through Translational DMPK and Model-Informed Pharmacokinetic Approaches, Nusrat Ahmed
Colostrum Extracellular Vesicle are Neuroprotective in the MPTP Intoxicated Mouse Model of Parkinson's Disease, Samia Akter
From Vector to Consequence: Integrating Vector Surveillance, Environmental Drivers, and Public Health Impact into Lyme Disease Risk Management, Kathleen E. Angell
Navigating the Divide: COVID-19 Vaccine Access, Uptake, and Persistent Vaccine Refusal in Nebraska, Julia Bai
Functional Importance of Pax5 and NrCAM in Highly Aggressive AR-Independent Prostate Cancer, Sreyashi Bhattacharya
A Novel Approach for Understanding the Role of Bone Remodeling in Early Structural Knee Osteoarthritis, Reece Blay
Development and Evaluation of the Cystiene Cathepsin Trapping Approach Incorporated in NTSR1- and FAP-Targeted Radiotherapeutics, Katherine Brake
Immunosuppression and Epigenetic Therapy: Amyloid Precursor-Like Protein 2-Mediated Macrophage Dynamics and Histone Deacetylase Inhibition in Neuroblastoma, Gabrielle L. Brumfield
Neuroplasticity in Motion: Exploring Neural Oscillatory Activity and Physical Therapy Interventions in Adolescents and Adults with Cerebral Palsy, Morgan T. Busboom-Matulka
Investigating the Effects of Transcription Factor Binding and Genetic Variants in the Striatum of Post-Mortem Cohorts with Opioid Use Disorder, Rajashree Chakraborty
Evaluating Current Practices in Operative Nontechnical Skills Training and Feedback in General Surgery Residency: A Mixed Methods Approach, Madeline Cloonan
Coordinating Connections: A Mixed-Methods Exploration of Relational Coordination and Interprofessional Team Development with Health Professions Students and Survivors of Stroke, Teresa Marie Cochran
Evaluating Clinical Competency in Undergraduate Nursing Students: A Mixed Methods Study, Emily C. Coffey
Variable Selection and Prediction Using Machine Learning Models in High-Dimensional Data, Apu Chandra Das
The Splicing Factor PTBP1 Interacts with RUNX1 and is Required for Leukemia Cell Survival, Arjun Dhir
The Design, Synthesis and Biological Evaluation of Novel 17β-Hydroxysteroid Dehydrogenase Modulators, Louise F. Dow
BET Protein Inhibition Relieves Myeloid-Derived Suppressor Cell-mediated Immune Suppression in Chronic Lymphocytic Leukemia, Erin M. Drengler
Neurodegenerative Disease Mechanisms: Mitochondrial Impairment, Tau Aggregation, and Neuroinflammation as Central Drivers of Disease Progression, Luis D. Estrella
Understanding Stakeholder Perspectives, Medical Student Metacognition and Reflections on Learning Order Entry in the Electronic Health Record, Abbey L. Fingeret
Multi-Modal MRI for the Pre-Clinical Evaluation of HIV-Linked Changes in the Central Nervous System, Gabriel Gauthier
A Comparison of Resurgence Following DRA and DRO, Alysa Georgopoulos
Navigating Nutrition Between Cultures: A Mixed Methods Study of Dietary Acculturation and Generational Status in Mexican-American Populations, Roger Gonzales
Role of Stabilin-1 Expressing Macrophages in Colorectal Liver Metastasis, Jampa L. Gurung
Investigate the Role of TGFβ3 in Regulating IRF6 and ΔNp63 in Periderm Desquamation, Nam Ha
Integrating Artificial Intelligence and Machine Learning with Causal Inference for Early Detection & Management of Cardiac Rejection, Roman G. Haynatzki
Temporal Patterns of Ectopic Pregnancy: Using the Electronic Health Record to Illuminate a Dark Corner in Women's Health, Kirsten Hepburn
An Extension of a Break-to-Choice Intervention with Isolated Contingency Tests for Children with Multiply Maintained Challenging Behavior, McKenna E. Herbek
Kinase Suppressor of Ras 2 Regulates Energy Balance and Tumor Initiation, Dianna H. Huisman
Optimal Two-Stage Phase II Bayesian Design, Yuanyuan Ji
Impact of Mesenchymal Stem Cell-Derived Chemokines and Other Tumor Microenvironment Factors in Bone-Metastatic Prostate Cancer, Catherine S. Johnson
Heart Failure in Rheumatoid Arthritis: Epidemiology, Determinants, and Gaps in Risk Stratification, Tate M. Johnson
Restoring Translational Control with Novel Small Molecule Activators of PP2A in Cancer Cells, Kayla A. Jonas
Leveraging Biomarkers to Accelerate Drug Development and Patient Care, Vineet A. Joshi
Development of Self-Assembled Polymeric Polyplexes for MicroRNA Delivery: Toward Treatment of Alcohol-Associated Liver Disease, Marjina Akter Kalpana
Neoadjuvant Gene Therapy with Calreticulin and R848: A Novel Approach to Pancreatic Ductal Adenocarcinoma Treatment, Ekta Kapoor
Targeting FOXM1/Aurora Kinase B Axis Attenuates Small Cell Lung Cancer Growth, Metastasis and Chemoresistance, Md Arafat Khan
Intrinsic and Extrinsic Drivers of Bioaerosol Decay: Investigating Pathogen Stability of Bacteriophage MS2, Sin Nombre Virus, and SARS-COV-2 in Simulated Environments, Elizabeth A. Klug
Assessment of Cellular Metabolism in Disease Progression and Prevention, Sai Sundeep Kollala
Elucidating the Mechanism of the Polymeric Drug PAMD-CH17’S Novel Anti-Leukemic Effects, Calvin Lam
Targeting TREM1: A Novel Therapeutic Approach to Mitigate Necrotizing Enterocolitis Injury in Murine Neonates, Zainab Damilola Lawal
The Impact of Teaching Multiple Responses on Resurgence of Target Behavior and Persistence of Alternative Responding, Brittany H. Loder-Lafferty
Drivers and Mechanisms of Golgi Fragmentation as a Modulator of Disease, Amanda Macke
Design and Synthesis of FDI-6-Based Hydrophobic Tag Degraders Targeting FOXM1, Callie J. Martin
Evaluating the Therapeutic Potential of Geranylgeranyl Diphosphate Synthase Inhibitor, RAM2061, in Myeloma Bone Disease, Molly Muehlebach
Demystifying Tumor-Mediated Local and Systemic Immunosuppression in Pancreatic Ductal Adenocarcinoma, Clara Mundry
Symptom Clusters and their Association with Health-Related Quality of Life in Pediatric Cancer Survivors After Treatment Completion, Krishtee Napit
Molecular Mechanisms of Aberrant Metabolism in Pancreatic Cancer Aggressiveness and Metastasis, Ayoola Ogunleye
Cholestasis and Fluid Flow are Biomechanic Regulators of Cholangiocarcinoma Progression, Andrew Oleksijew
Effects of Treatment Integrity Level and Error Type on Dro Efficacy: A Parametric and Comparative Analysis, Paige O'Neill
Combinatorial Antiviral Regimen as Strategy to Control SARS-CoV-2 Infections, Kabita Pandey
Novel Drug Delivery Platforms for Small Molecule and miRNA-Based Therapies in Acute Myeloid Leukemia, Qiaoyu Pan
Optimizing Geranylgeranyl Diphosphate Synthase Inhibitor (GGSI) Therapy for Multiple Myeloma, Ashruti Pant
Study of Peptide Amphiphiles as Antimicrobial Agents, Aramis J. Pereira
Eating the Fat of the Land: The Work of Coxiella burnetii To Traverse Intracellular Lipid Landscapes, Charlie Porto
Claudin-1-Mediated Signaling and Therapy Resistance in Colorectal Cancer: From Mechanism to Translation, Mark W. Primeaux
Dissecting MUC16 in Pancreatic Cancer: Imaging Targetability, Oncogenic Signaling and Immune Suppression, Christabelle Rajesh
Decoding IPMN: Exploring the Molecular Bridges of Pancreatic Cancer Progression, Pratima Raut
Investigating the Role of Androgen Deprivation on AXL Regulation in Prostate Cancer, Amanda Robotham
Apolipoprotein E4, Tauopathy, and Brain Injury: Molecular Insights into Alzheimer's Disease Pathology, Nashanthea J. Roland
Validating the Ability of IAG933 to Block the Interaction of YAP1 and TEAD in Ovarian Cancer Cells, Alex Sage
Targeting Metabolic and Heme Degradation Pathways in Prostate Cancer: A New Therapeutic Strategy, Dania Sahtout
Cross-Cultural Care in Perinatal Nursing, Erin Salahshurian
Cardiovascular Disease Risk, Risk Factors, and Healthcare Utilization Among Latino Male Migrant Farmworkers in Nebraska, Maria Jose Sanchez Roman
Analyzing Food Access: An Investigation of Food Insecurity amongst Latinos in Rural Nebraska, Natalia Santos
Characterization and Identification of Staphylococcus Aureus Pyruvate Transporters, Cleofes Sarmiento
Multilineage Hematopoietic Function of SAM-Containing Proteins, Meg Schaefer
Staphylococcus aureus Encodes Multiple Arginine Transporters, Gabrielle Schulze
Identification and Preclinical Assessment of Novel Therapeutic Modalities in Environmental Exposure-induced Lung Disease, Aaron D. Schwab
Targeting Human Bromodomain Proteins for the Treatment of Medulloblastoma, Zalak Sheth
Evaluation of the Gut Microbiome in Chronic Lymphocytic Leukemia: Disease Insights and Potential Therapeutic Avenues, Sydney Skupa
Coxiella burnetii Manipulation of Membrane Contact Sites in the Intracellular Niche, Margaret F. Sladek
A Replication and Extension of the Enhanced Choice Model for Children Who Exhibit Challenging Behavior, Jessica Tran
The Characterization of Per- and Polyfluoroalkyl Substances (PFAS) in Nebraska Drinking Water and Human Health Impacts, Sarah Tucker
Mucin-type O-glycans Protects Against Pancreatitis, Khadija Turabi
Behavior Analysts’ Training and Practices Regarding Cultural Diversity: A Replication and Extension, Tania M. Valdez-Nuguid
Immunoplasticity: A Key Determinant in the Outcome of Neurosurgical Biofilm Infection, Zachary A. Van Roy
Variable Selection with False Discovery Rate Control in High-Dimensional Data, Runqiu Wang
The Chlamydia trachomatis Inclusion Membrane as the Confluence between a Pathogen and Its Host, Ray E. Widner
Facilitators of Routine Cervical Screening Receipt for Women With Intellectual and Developmental Disabilities in Nebraska, Anne Woodruff Jameson
An Integrative Multi-Omics Approach for Enhanced Alzheimer's Disease Diagnosis, Hanyu Xiao
Evaluation of the Usage and Effectiveness of the Gross Anatomy Osteology e-Learning Module, Conor Young
CXCR4 Cell and Lymphoid Targeted CRISPR-Cas9 Lipid Nanoparticles Facilitate HIV-1 Proviral DNA Excision in CD4+ T cells, Lubaba A. Zaman
Theses/Dissertations from 2024
Bio-Preparedness in a Global Context: Multi-Site International Study Investigating Global Health Security Challenges in Egypt, Oman, and the United States, Rima M. Al Balushi
Characterization of Population Pharmacokinetics and Associated Interindividual Variability of Drugs Used in Mass Drug Administration against Lymphatic Filariasis, Abdullah Alshehri